Showing 297 open source projects for "rna"

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  • 1

    mRNA

    mRNA sequencing and translating to proteins

    The use is prompt to input a DNA sequence which gets transcribed into mRNA and translated into proteins. The user can also input the RNA sequence which will give the DNA associated with it and will also translate it to proteins. The program utilizes the fun and easy to use GUI to make RNA sequencing accessible to all.
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  • 2

    ISVASE

    identification of sequence variant associated with splicing event

    To generate correct mature mRNAs, the exons must be identified and joined together precisely and efficiently by RNA splicing mechanism. It is to be noted that about one third or a half of all disease-causing mutations effect RNA splicing. However, there is little bioinformatics tools to directly identify sequence variants associated with splicing events (SVASE) based on RNA-seq data. We developed ISVASE, a simple and convenient tool for identifying SVASE directly using RNA-seq data. Comparing...
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  • 3

    GenomeDatabase

    For creating a local database of reference genomes

    Genome Database - A tool to create a local database of reference genome sequences Usage: java path/to/GenomeDatabase.jar [options] By Marc Strous, 2016 This tool enables you to download fasta files of protein and RNA sequences encoded in reference genomes at NCBI. You can select relevant genomes with a set of queries. Each query has four fields, separated by comma's. Example of a queries are: superkingdom,Bacteria,genus,ftp superkingdom,Archaea,genus,ftp superkingdom,Eukaryota,phylum,ftp...
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  • 4
    INTEGRATE
    INTEGRATE: Calling gene fusions with exact fusion junctions and genomic breakpoints by combining RNA-Seq and WGS data. To download source code, reference manual and test case, please go to 'Files'. Also refer to 'Wiki' for details.
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    SysAid multi-layered ITSM solution

    For organizations spanning all industries and sizes from SMBs to Fortune 500 corporations

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  • 5

    MITP

    MITP - conserve & novel miRNA identification & target prediction tool

    miRNA is a widely known small non-coding RNA which can mediate gene regulation of most important biological processes in plants and animals. Therefore, identification conserve and novel miRNA and their target genes in model and new sequenced species are inevitable. MITP is designed to identify miRNA easily and faster based on sequence mapping result from any mapping software which producing SAM format output result, blast result (default output result) or blat result (default output result...
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  • 6

    VoltMR

    Pure java NGS mapping soft run on Hadoop 2.0

    VoltMR is pure java NGS (DNA/RNA) mapping and realignment soft that run on Hadoop 2.0 The accuracy is comparable to BWA-MEM and novoalgin with speed faster than those aligner. Using 100 core, VoltMR finish typical exome sample (10GB),mapping, sort, mark duplicate, local realignment in 30 minitue. It use about 10GB to 15GB RAM for each hadoop mapper and reducer. Currently, VoltMR take fastq as a input and output bam/ADAM format. For DNA mapping, GATK compatible realignment/recalbration...
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  • 7
    CoverageAnalyzer

    CoverageAnalyzer

    RNA modification detection by RT signatures in deep sequencing data

    Combination of reverse transcription (RT) and deep sequencing has emerged as a powerful instrument for detection of RNA modifications, a field that has seen a recent surge in activity because of its importance in gene regulation. Recent studies yielded high-resolution RT signatures relying on both, sequence dependent mismatch patterns and RT arrests. Common alignment viewers lack in specialized functionality, such as filtering, tailored visualization, differential analysis and export...
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  • 8

    mirPRo

    Tool for miRNA-seq analysis in C++

    mirPRo is a tool for miRNA-seq analysis. It can quantify known and novel miRNAs in single-end RNA-seq data and provide useful functions such as IsomiR detection and "arm switching" identification, miRNA family quantification, and read cataloging in terms of genome annotation. mirPRo only works for species that has reference genome. [1] Who are we? Please visit our website http://bioinfolab.miamioh.edu [2] How to cite mirPRo? Shi J, Dong M, Li L, Liu L, Luz-Madrigal A, Tsonis PA, Rio-Tsonis...
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  • 9
    An ultrafast and versatile algorithm that searches for potential off-target sites of CRISPR/Cas-derived RNA-guided endonucleases. Cas-OFFinder is an ultrafast and highly versatile off-target searching tool. Importantly, Cas-OFFinder is written in OpenCL, enabling operation in diverse platforms such as central processing units (CPUs), graphics pro-cessing units (GPUs), digital signal processors (DSPs), and other processors. Cas-OFFinder runs on Windows and POSIX (portable operating system...
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    Downloads: 37 This Week
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  • 10
    SpliceSim is a collection of Python scripts designed for realistic simulation of RNA-seq reads for in silico differential AS studies. For software support and information on their distribution licenses, please proceed to: https://github.com/mingjiewong/SpliceSim
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  • 11
    ds-Bidens

    ds-Bidens

    Software for studying bacterial colony features

    Software for studying bacterial colony features: Optical forward-scattering systems supported by image analysis methods are increasingly being used for rapid identification of bacterial colonies. The conventional detection and identification of bacterial colonies comprises a variety of methodologies based on biochemical, serological or DNA/RNA characterization. Such methods involve laborious and time-consuming procedures in order to achieve confirmatory results. The software (ζ-Bidens...
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  • 12
    Several RNA and protein structure volume calculation tools.
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  • 13
    ChIP-RNA-seqPRO

    ChIP-RNA-seqPRO

    ChIP-RNA-sequencing-processing (ChIP-RNA-seqPRO)

    ChIP-RNA-seqPRO: A strategy for identifying regions of epigenetic deregulation associated with aberrant transcript splicing and RNA-editing sites. Runnable python scripts packaged together with customized annotation libraries, demo data input and README guide. 9/26 : v1.1 Updated MAIN_IV to debug error thrown by python pandas no longer supporting 'subset'. This code will no longer be actively maintained/updated here. A cloud-based resource for comparative analysis of epigenetic, sequence...
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  • 14
    KAnalyze

    KAnalyze

    DNA/RNA Sequence K-mer Toolkit

    KAnalyze is a Java toolkit designed to convert DNA and RNA sequences into k-mers. It is both a command line application and an API.
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  • 15
    Protospacer Workbench

    Protospacer Workbench

    CRISPR/Cas9 guide-RNA design

    Protospacer Workbench helps to design, analyze, and share CRISPR target-sites for any organism or set of FASTA formatted sequences. Design of guide-RNAs for the CRISPR/Cas genome editing system is intuitively easy, but computationally difficult. The main difficulty arises from the need to identify potential off-targets that may be quite different from the intended target. Current online tools for guide-RNA design provide a user friendly interface to sequence mapping software such as Bowtie...
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  • 16
    iSRAP is an integrated Small RNA-seq Analysis Pipeline that aims to assess sequence quality and examine differentially expressed microRNA and other small non-coding RNAs.
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  • 17

    REDO

    REDO - RNA Editing Detection in Organelle

    REDO is a comprehensive application tool for identifying RNA editing events in organelles based on variant call results (VCF files). It is a suite of Perl scripts and can work easily and directly in any operating system installed Perl and R Environment. The stringent rule depended filters and statistical filters are used in REDO for reducing false positive rate. It can provide detailed annotations, statistics and figures for RNA editing sites. REDO also can detect RNA editing events in multiple...
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  • 18
    EricScript
    Ericscript is a computational framework to detect gene fusions from paired end RNA-seq data with high sensitity and specificity.
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  • 19
    Protein Expression Control Analysis (PECA) is a statistical software to identify genes subject to significant RNA- and protein-level regulation with control of false discovery rate.
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  • 20

    mRIN

    Assessing mRNA integrity directly from RNA-Seq data

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  • 21

    allim

    Allelic imbalance meter (Allim), a new tool for measuring allele speci

    Allim, Allelic imbalance meter, offers an integrated and user-friendly solution for measuring allele specific gene expression (ASE) within species. Allim estimates allelic imbalance in F1 hybrids. Since mapping bias is the largest problem for reliable estimates of allele specific gene expression using RNA-seq, Allim combines two different measures to account for mapping biases. First, Allim generates a polymorphism aware reference genome that accounts for the sequence variation between...
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  • 22

    treelet_webdemo

    treelet webdemo for RNA data

    Application to showcase RNA analysis tools using multidimensional processing via tree-wavelet. It encompasses the tree-generation, classification with a wrapper algorithm , and with an ensemble algorithm. Both specifically built for RNA data processing.
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  • 23

    scell

    single-cell RNA-seq analysis software

    SCell is an integrated software tool for quality filtering, normalization, feature selection, iterative dimensionality reduction, clustering and the estimation of gene-expression gradients from large ensembles of single-cell RNA-seq datasets. SCell is open source, and implemented with an intuitive graphical interface. Binary executables for Windows, MacOS and Linux are available at http://sourceforge.net/projects/scell, source code and pre-processing scripts are available from https...
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  • 24

    LivMach Framework

    A virtual organism simulation framework written in C++

    This is a C++ code to simulate life processes and responses to external stimulii in multicellular organisms by replicating the data flow in an actual organism using a straightforward approach. It can simulate both stimulus response and life processes(like respiration,excretion etc.) at the same time using multi-threading techniques. Digital DNA simulation- translation and transcription of DNA template to RNA is now supported. Users can also simulate cells and tissues using inbuilt classes.
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  • 25

    Deep Sense

    Web-interface Application for DE pipelines in RNA-seq studies

    Deep Sense is a collection of open-source R web-interface applications designed for fast, simple and convenient comparisons and performance analyses of gene-level DE results from RNA-seq studies with 7 R/ Bioconductor DE pipelines: edgeR, DESeq, DESeq2, NOISeq, baySeq, EBSeq and SAMseq where users are allowed to adjust the appropriate settings for the threshold FDR values and the type of normalization procedures for their experimental needs. For software support and information...
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