Showing 190 open source projects for "rna"

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  • 1
    FastQC

    FastQC

    A quality control analysis tool for high throughput sequencing data

    ... then direct you to where your data may have problems and allow you to take necessary steps to correct it before doing any further analysis. FastQC is not tied to any specific type of sequencing technique, so it can be used to look at libraries of various experiment types (Genomic Sequencing, ChIP-Seq, RNA-Seq, BS-Seq etc etc).
    Downloads: 64 This Week
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  • 2
    kallisto

    kallisto

    Near-optimal RNA-Seq quantification

    kallisto is a program for near-optimal quantification of transcript abundances from RNA-Seq data, or more generally of target sequences using high-throughput sequencing reads. It is based on the idea of using pseudoalignment to quickly determine reads and targets’ compatibility, with no need for alignment. According to benchmarks done on a Mac desktop computer, kallisto can quantify 30 million human bulk RNA-seq reads in less than 3 minutes with just the read sequences and a transcriptome...
    Downloads: 2 This Week
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  • 3
    awesome-single-cell

    awesome-single-cell

    Community-curated list of software packages and data resources

    Community-curated list of software packages and data resources for single-cell, including RNA-seq, ATAC-seq, etc. List of software packages (and the people developing these methods) for single-cell data analysis, including RNA-seq, ATAC-seq, etc. Rapid, accurate and memory-frugal preprocessing of single-cell and single-nucleus RNA-seq data. Find bimodal, unimodal, and multimodal features in your data. Ascend is an R package comprised of fast, streamlined analysis functions optimized to address...
    Downloads: 0 This Week
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  • 4
    harmonypy

    harmonypy

    Integrate multiple high-dimensional datasets with fuzzy k-means

    Harmony is an algorithm for integrating multiple high-dimensional datasets. harmonypy is a port of the harmony R package by Ilya Korsunsky. Harmony is a general-purpose R package with an efficient algorithm for integrating multiple data sets. It is especially useful for large single-cell datasets such as single-cell RNA-seq.
    Downloads: 0 This Week
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  • 5

    CPAT

    RNA coding potential assessment tool

    Using RNA-seq, tens of thousands of novel transcripts and isoforms have been identified (Djebali, et al Nature, 2012 , Carbili et al, Gene & Development, 2011) The discovery of these hidden transcriptome rejuvenate the need of distinguishing coding and noncoding RNA. However, Most previous coding potential prediction methods heavily rely on alignment, either pairwise alignment to search for protein evidence or multiple alignments to calculate phylogenetic conservation score (such as CPC...
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    Downloads: 13 This Week
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  • 6

    RSeQC

    RNA-seq data QC

    RSeQC provides a number of functions to evaluate the quality of RNA-seq data. http://rseqc.sourceforge.net/
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    Downloads: 218 This Week
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  • 7

    PLEKv2

    PLEKv2: predicting lncRNAs and mRNAs

    PLEKv2: predicting lncRNAs and mRNAs based on intrinsic sequence features and the Coding-Net model INSTALLATION ------------- We upgraded PLEK to PLEKv2. All you need is RNA sequences (fasta file). Steps: 1. Download PLEK.2.1.tar.gz from * and decompress it. $ tar zvxf PLEK.2.1.tar.gz 2. Compile PLEK2.1 $ cd PLEK2.1 3. decompress Coding_Net_kmer6_orf.h5.bz2 model $ bunzip2 Coding_Net_kmer6_orf.h5.bz2 4. decompress Coding_Net_kmer6_orf_Arabidopsis.h5.bz2 model $ bunzip2
    Downloads: 145 This Week
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  • 8
    relax

    relax

    Molecular dynamics by NMR data analysis

    The software package 'relax' is designed for the study of molecular dynamics through the analysis of experimental NMR data. Organic molecules, proteins, RNA, DNA, sugars, and other biomolecules are all supported. It supports exponential curve fitting for the calculation of the R1 and R2 relaxation rates, calculation of the NOE, reduced spectral density mapping, the Lipari and Szabo model-free analysis, study of domain motions via the N-state model and frame order dynamics theories using...
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    Downloads: 57 This Week
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  • 9
    Weinberg-R2R

    Weinberg-R2R

    Faster creation of aesthetic RNA secondary structure diagrams

    R2R is a program to assist in aesthetic drawings of RNA secondary structures. It is primarily aimed at drawing consensus diagrams, but can also draw single RNA molecules. R2R is freely available under the GNU Public License, and runs as a command-line program under UNIX-like systems such as Linux, MacOS Darwin or Cygwin on Windows. R2R was written by Zasha Weinberg. If you use it, please cite this paper: http://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-12-3
    Downloads: 17 This Week
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  • 10

    rna-test

    script for variant calling of RNA-Seq

    rna_test.sh is a shell script to run GATK best practice for variant-calling in RNAseq. It uses STAR2.5 for alignment, HaplotypeCaller to call variants, and Annovar to annotate. It also employs STAR-Fusion, Cufflinks and Stringtie FPKM, HTSeq_count and BAM-readcount. Notice: STAR_gene_read and HTSeq_count are added. exac03nontcga is added. STAR-Fusion is added. Stringtie is added. Disable BQSR (-skb) opteion is added. New avsnp(150) is updated. use -dcov in SplitNCigarReads...
    Downloads: 2 This Week
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  • 11
    sRNAWorkbench

    sRNAWorkbench

    The UEA sRNA Workbench

    A suite of tools for analysing small RNA (sRNA) data from Next Generation Sequencing devices. Including expression profiling of known mirco RNA (miRNA), identification of novel miRNA in deep-sequencing data and identification of other interesting landmarks within high-throughput genetic data
    Downloads: 5 This Week
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  • 12

    miRge3

    Comprehensive analysis of small RNA sequencing data

    An update to Python package to perform comprehensive analysis of small RNA sequencing data, including miRNA annotation, A-to-I editing, novel miRNA detection, isomiR analysis, visualization through IGV, processing Unique Molecular Identifieres (UMI), tRF detection and producing interactive graphical output. miRge3.0 is developed in python v3.8 and is a recent update of our previous version miRge2.0. This build includes command line interface (CLI) and cross-platform Graphical User Interface...
    Downloads: 5 This Week
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  • 13
    OmicSelector

    OmicSelector

    Feature selection and deep learning modeling for omic biomarker study

    OmicSelector is an environment, Docker-based web application, and R package for biomarker signature selection (feature selection) from high-throughput experiments and others. It was initially developed for miRNA-seq (small RNA, smRNA-seq; hence the name was miRNAselector), RNA-seq and qPCR, but can be applied for every problem where numeric features should be selected to counteract overfitting of the models. Using our tool, you can choose features, like miRNAs, with the most significant...
    Downloads: 0 This Week
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  • 14

    TileCreator

    A soft for designing primers for overlapping tiles over a transcript.

    .... # Considerations - Only for MacOS for the moment. - Takes a very long time to open, but then it should work fine. - Only accepts DNA sequences as input ("T", not "U"). - It does not check for primer specificity nor primer dimers. - It is based on the original olaygo.py script found in seismic-rna by Matthew F. Allan (please check the Rouskin Lab repository).
    Downloads: 0 This Week
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  • 15

    HipMer

    A High performance distributed memory assembler for big genomic data

    ... and accuracy in metagenomic assemblies. It is able to reconstruct rRNA elements via a separate algorithm which relies on reference SSU and LSU Hidden Markov Models to help traverse the contig graph around ribosomal RNA regions. For more information and publications visit the HipMer Portal (http://portal.nersc.gov/project/hipmer/) MetaHipMer is one component of the ExaBiome project (https://sites.google.com/lbl.gov/exabiome/home), part of the Exascale Computing Project: https://www.exascaleproject.org/
    Downloads: 6 This Week
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  • 16
    Tiglon is a transcriptome assembler via integrating alignments of different RNA-seq reads aligners.
    Downloads: 0 This Week
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  • 17
    CStone

    CStone

    Short-read de novo assembler that identifies chimeric contigs.

    > CStone wiki: https://sourceforge.net/p/cstone/wiki/Home/ Related Software: 1. CStone: (See wiki) 2. CSReadGen: https://sourceforge.net/projects/csreadgen/ 3. CView: https://sourceforge.net/projects/cview/ 4. ChimSim: https://sourceforge.net/projects/chimsim/ 5. TVScript: https://sourceforge.net/projects/tvscript/
    Downloads: 0 This Week
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  • 18
    CSReadGen

    CSReadGen

    RNA-Seq read simulator that offers a wide range of parameter options.

    > CSReadGen wiki: https://sourceforge.net/p/csreadgen/wiki/Home/ Related software: 1. CStone: https://sourceforge.net/projects/cstone/ 2. CSReadGen: (See wiki) 3. CView: https://sourceforge.net/projects/cview/ 4. ChimSim: https://sourceforge.net/projects/chimsim/ 5. TVScript: https://sourceforge.net/projects/tvscript/
    Downloads: 0 This Week
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  • 19

    CIRI

    CircRNA Identifier. A de novo circular RNA identification tool

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    Downloads: 59 This Week
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  • 20
    Downloads: 0 This Week
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  • 21

    scDAPA

    Detection and visualization of dynamic alternative polyadenylation

    ... of dynamic alternative polyadenylation from single cell RNA-seq data. Bioinformatics, 36(4): 1262–1264. https://doi.org/10.1093/bioinformatics/btz701
    Downloads: 5 This Week
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  • 22

    miRSim

    Seed-based RNA-Seq Simulator

    The miRSim tool can generate the synthetic RNA-Seq data in standard fastq/fasta format by utilizing the sequence-specific properties (i.e., seed and xseed (remaining part of the sequence after removing seed)). Additionally, miRSim also generates the ground truth in CSV format that provides information about genomic location, CIGAR string, sequence, and expression counts.
    Downloads: 0 This Week
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  • 23
    GUIdEStaR: G-quadruplex (GQ) provided by Chariker et al., uORF from uORF-Tools, IRES from IRESbase, Epigenetic modification from Met-DB V2.0 and Choi et al., Small RNA from DASHR 2.0, and Repeats from RepeatMasker For details, please read the main article at https://www.biorxiv.org/content/10.1101/2021.02.25.432957v3
    Downloads: 0 This Week
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  • 24
    Cell Paint

    Cell Paint

    cellPAINT allows users to create living illustrations of biology.

    cellPAINT is a free-form painting app that allows users to create their own living illustrations of cellular landscapes. There are currently several prototypes available: --cellPAINT_coronavirus includes a newly-redesigned user interface, and molecular building blocks for coronavirus, blood plasma, and a simple human cell --cellPAINT_exo includes hand-painted sprites created by Julia Jimenez during an internship, and also allows input of custom sprites through Mesoscope --cellPAINT_VR is a...
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    Downloads: 21 This Week
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  • 25
    Lexical Analyzer Generator Quex

    Lexical Analyzer Generator Quex

    Generator of lexical analyzers in C and C++. Unicode Supported.

    The goal of this project is to provide a generator for lexical analyzers of maximum computational efficiency and maximum range of applications. This includes the support for Unicode (UTF8, UTF16, ...) and a large variety of other encodings directly and via nested converters such as ICU(tm) and IConv. Sophisticated buffer handling allows to operate on plain file streams, on sockets, or manually fed buffer content. 'Ready-to-build' examples explain related concepts and facilitate practical...
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    Downloads: 21 This Week
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