Open Source Python Scientific/Engineering Software - Page 5
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Python Scientific/Engineering Software
View 202 business solutionsBrowse free open source Python Scientific/Engineering Software and projects below. Use the toggles on the left to filter open source Python Scientific/Engineering Software by OS, license, language, programming language, and project status.
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Demo Series - Small Business Backup By VeeamWatch this on-demand demo series and learn how to protect your Microsoft 365 data with clear, simple, actionable steps that are easy to implement for businesses of all sizes.
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MongoDB Atlas runs apps anywhereMongoDB Atlas gives you the freedom to build and run modern applications anywhere—across AWS, Azure, and Google Cloud. With global availability in over 115 regions, Atlas lets you deploy close to your users, meet compliance needs, and scale with confidence across any geography.
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XCSoar
... the open-source glide computer
XCSoar is a tactical glide computer for Android, Linux, macOS, and Windows. -
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This project is for maintaining a linux system that concentrates on math, logic, and geometry related softwares.
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asammdf
Fast Python reader and editor for ASAM MDF / MF4 (Measurement Format)
*asammdf* is a fast Python parser and editor for ASAM (Associtation for Standardisation of Automation and Measuring Systems) MDF / MF4 (Measurement Data Format) files. It supports MDF versions 2 (.dat), 3 (.mdf) and 4 (.mf4). *asammdf* works on Python 2.7, and Python >= 3.4 -
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MAGeCK
Model-based Analysis of Genome-wide CRISPR-Cas9 Knockout
MAGeCK2 is here: https://github.com/davidliwei/mageck2 Model-based Analysis of Genome-wide CRISPR-Cas9 Knockout (MAGeCK) is a computational tool to identify important genes from the recent genome-scale CRISPR-Cas9 knockout screens technology. For instructions and documentations, please refer to the wiki page. MAGeCK is developed by Wei Li and Han Xu from Dr. Xiaole Shirley Liu's lab at Dana-Farber Cancer Institute/Harvard School of Public Health, and is maintained by Wei Li lab at Children's National Medical Center. We thank the support from Claudia Adams Barr Program in Innovative Basic Cancer Research and NIH/NHGRI to develop MAGeCK. -
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Earth Enterprise
Google Earth Enterprise - Open Source
Earth Enterprise is the open source version of Google Earth Enterprise (GEE), a powerful geospatial application suite that enables organizations to build and host custom 3D globes and 2D maps using their own imagery and data. Unlike Google Maps or Google Earth, Earth Enterprise does not include Google’s proprietary imagery but instead provides the tools needed to manage and visualize private geospatial datasets. The system is composed of three main components: Fusion, which processes and integrates imagery, vector, and terrain data into unified map layers; Server, which hosts the resulting globes or maps via Apache or Tornado-based web servers; and Client, which includes the Google Earth Enterprise Client (EC) for 3D visualization and the Google Maps JavaScript API V3 for 2D viewing. Designed for enterprise, research, and government use, it allows for secure, scalable deployment of geospatial visualization systems within private infrastructure. -
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MuJoCo-py
mujoco-py allows using MuJoCo from Python 3
mujoco-py is a Python wrapper for MuJoCo, a high-performance physics engine widely used in robotics, reinforcement learning, and AI research. It allows developers and researchers to run detailed rigid body simulations with contacts directly from Python, making MuJoCo easier to integrate into machine learning workflows. The library is compatible with MuJoCo version 2.1 and supports Linux and macOS, while Windows support has been deprecated. It provides utilities for loading models, running simulations, and accessing simulation states in real time, along with visualization tools for rendering environments. The project also includes interactive examples showcasing collision handling, texture randomization, state resetting, and robot control. By bridging MuJoCo with Python, mujoco-py enables rapid prototyping, training, and evaluation of AI agents in physics-rich environments. -
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Pootle Django
Online translation tool
Pootle is written in Python using the Django framework and therefore can be installed on any web server that supports serving WSGI applications. Key localization file formats are supported, including Gettext PO, XLIFF, Java .properties, PHP arrays and many more supported by the Translate Toolkit. Ensures the best quality localizations by automatically detecting common errors made by translators. Integrates user suggestions, terminology, Translation Memory, Machine Translation, and more. A number of translation projects for a number of languages can be hosted on Pootle. Teams can manage their files, permissions, projects, and translate on-line. Files can be downloaded for offline translation. Delegate to your translators and allow them to commit directly to your version control systems. Pootle can easily be adapted and integrated into your existing web look and feel. -
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Protenix
A trainable PyTorch reproduction of AlphaFold 3
Protenix is an open-source, trainable PyTorch reimplementation of AlphaFold 3, developed by ByteDance with the goal of democratizing high-accuracy protein structure prediction for computational biology and drug-discovery research. Protenix provides a complete pipeline for turning protein sequences (with optional MSA / sequence alignment) or structural inputs (e.g. PDB/CIF) into full 3D atomic-level structure predictions. It supports both “full” models and lightweight variants such as “Protenix-Mini,” offering a trade-off between speed/compute cost and predictive accuracy — making structure prediction accessible even in resource-constrained environments. The project also includes support for constraints (e.g., specifying residue- or atom-level contact constraints, or pocket constraints) to guide predictions toward biologically or experimentally relevant conformations, which enhances its utility for tasks like modeling complexes, ligands, or antibody–antigen interactions. -
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ROMM
A beautiful, powerful, self-hosted rom manager and player
ROMM is an Android productivity launcher replacement that focuses on giving users faster, easier access to apps, contacts, and information through intuitive gestures, smart search, and contextual suggestions. It reimagines the home screen with adaptive layouts, predictive app recommendations, and dynamic organization so that frequently used tools are always within reach. The launcher includes a powerful universal search that combs through installed apps, contacts, messages, and web results to deliver quick answers without switching contexts. Romm also supports widgets, customization options, and theme choices so users can tailor the visual experience to their preferences while maintaining performance and responsiveness. Privacy is a highlight, with local indexing and search functions that operate without sending data to external servers unless explicitly permitted. -
AI-generated apps that pass security reviewRetool lets you generate dashboards, admin panels, and workflows directly on your data. Type something like “Build me a revenue dashboard on my Stripe data” and get a working app with security, permissions, and compliance built in from day one. Whether on our cloud or self-hosted, create the internal software your team needs without compromising enterprise standards or control.
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Segments.ai
Segments.ai Python SDK
Multi-sensor labeling platform for robotics and autonomous vehicles. The platform for fast and accurate multi-sensor data annotation. Label in-house or with an external workforce. Intuitive labeling interfaces for images, videos, and 3D point clouds (lidar and RGBD). Obtain segmentation labels, vector labels, and more. Our labeling interfaces are set up to label fast and precise. Powerful ML assistance lets you label faster and reduce costs. Integrate data labeling into your existing ML pipelines and workflows using our simple yet powerful Python SDK. Onboard your own workforce or use one of our workforce partners. Our management tools make it easy to label and review large datasets together. Now, Segments.ai is providing a data labeling backbone to help robotics and AV companies build better datasets. -
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The Missing Semester
The Missing Semester of Your CS Education
The Missing Semester is a course and repository that teaches the engineering skills often skipped in traditional computer science curricula: command-line fluency, shell scripting, editors, version control, debugging, data wrangling, and automation. It includes lecture notes, exercises, and sample solutions that encourage hands-on practice rather than passive reading. The curriculum demystifies tools like bash, vim, git, and make, showing how to combine them into efficient workflows that scale from homework to production systems. Lessons dig into practical topics such as environment management, job control, shell pipelines, profiling, and reproducibility, with an emphasis on habits that save time and prevent errors. The materials are designed to be approachable for beginners yet still valuable to advanced users who want to sharpen their tooling. By the end, learners can work faster and more reliably because they understand the mechanics of their everyday tools. -
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Violin
Open-source Video Translation Skill
Violin is an open-source video translation and dubbing tool that turns existing videos into localized versions with translated voice-over and optional subtitles. It transcribes the original speech, translates the text, generates natural-sounding speech in the target language, and remuxes the new audio back into the video. The project is designed to keep the generated speech aligned with the original timing so the final result feels closer to a real dubbed video. It can be used from the command line, through a FastAPI web app, or as a Claude Code skill. Violin supports multilingual workflows and is useful for creators, educators, localization teams, and developers building automated video translation pipelines. It is especially practical for turning lectures, tutorials, interviews, demos, and social videos into accessible content for wider audiences. -
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Complete manufacturing automation platform for factory and process equipment. It includes multi-protocol communications (including Modbus/TCP), PLC soft logic, HMI, and tools for troubleshooting and installation in 4 comprehensive packages.
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The Player Project: Player is a networked interface to robots and sensors. Stage and Gazebo are Player-friendly multiple-robot simulators. The software aims for POSIX compliance and runs on most UNIX-like OS's. Some parts also work on Windows.
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Automatically geocode pictures from your camera and a GPS track log. Following Google code closure the only official webpage is (doc, support, code) : https://github.com/notfrancois/GPicSync
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A free, industrial quality library for simulating articulated rigid body dynamics - for example ground vehicles, legged creatures, and moving objects in VR environments. It's fast, flexible & robust. Built-in collision detection.
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PowerTalk automatically speaks Microsoft PowerPoint presentations. For presenters who find speaking difficult, audiences containing people with visual impairments and fun educational uses. Uses synthesised computer speech provided with Windows
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GNU Health
GNU Health - The Free/Libre Hospital and Health Information System
GNU Health is the award-winning Hospital and Health Information System (HIS), declared a Digital Public Good and adopted by the United Nations . GNU Health Hospital and Lab information system is used by academic and research institutions around the globe. It is also used in public health system of countries such as Argentina, India, Jamaica, Laos, Cameroon, Suriname. GNU Health is an official GNU project. GNU Health is brought to you by GNU Solidario, an Non-Profit Organization (NGO) that focuses in Social Medicine. -
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QtiPlot is a user-friendly, platform independent data analysis and visualization application similar to the non-free Windows program Origin.
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Open Automation
Building automation (like KNX or OpenHAB) software (like CometVisu).
This project aims to provide software usefull in automation tasks like building automation. Different backends are supported like KNX or OpenHAB. Note: The project has moved to GitHub. Please consult: https://github.com/CometVisu/CometVisu - for the CometVisu https://github.com/OpenAutomationProject - for the different OpenAutomation subprojects -
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OpenOPC for Python is an easy to use OPC (OLE for Process Control) library for use with the Python programming language. The project includes a Windows gateway service allowing non-Windows clients to also access OPC-DA calls.
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BioNeMo
BioNeMo Framework: For building and adapting AI models
BioNeMo is an AI-powered framework developed by NVIDIA for protein and molecular generation using deep learning models. It provides researchers and developers with tools to design, analyze, and optimize biological molecules, aiding in drug discovery and synthetic biology applications. -
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Brax
Massively parallel rigidbody physics simulation
Brax is a fast and fully differentiable physics engine for large-scale rigid body simulations, built on JAX. It is designed for research in reinforcement learning and robotics, enabling efficient simulations and gradient-based optimization. -
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Get Physics Done (GPD)
The first open-source agentic AI physicist
Get Physics Done (GPD) is an open-source project designed to accelerate scientific research in physics by leveraging modern computational tools and automation techniques. It aims to simplify the process of performing simulations, calculations, and experimental analysis by providing structured workflows that integrate computational physics methods with reproducible research practices. The project focuses on reducing the friction involved in setting up experiments, running simulations, and analyzing results, allowing researchers to focus more on scientific insight rather than infrastructure. It emphasizes automation and reproducibility, ensuring that experiments can be easily replicated and extended by other researchers. The framework is adaptable to different areas of physics, making it suitable for both theoretical and applied research scenarios. -
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JAX
Composable transformations of Python+NumPy programs
With its updated version of Autograd, JAX can automatically differentiate native Python and NumPy functions. It can differentiate through loops, branches, recursion, and closures, and it can take derivatives of derivatives of derivatives. It supports reverse-mode differentiation (a.k.a. backpropagation) via grad as well as forward-mode differentiation, and the two can be composed arbitrarily to any order. What’s new is that JAX uses XLA to compile and run your NumPy programs on GPUs and TPUs. Compilation happens under the hood by default, with library calls getting just-in-time compiled and executed. But JAX also lets you just-in-time compile your own Python functions into XLA-optimized kernels using a one-function API, jit. Compilation and automatic differentiation can be composed arbitrarily, so you can express sophisticated algorithms and get maximal performance without leaving Python.
