Showing 56 open source projects for "protein"

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  • 1
    The Sashimi project hosts the Trans-Proteomic Pipeline (TPP), a mature suite of tools for mass-spec (MS, MS/MS) based proteomics: statistical validation, quantitation, visualization, and converters from raw MS data to the open mzML/mzXML formats.
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    Downloads: 43 This Week
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  • 2

    EvidentialGene

    Evidence Directed Gene Construction for Eukaryotes

    ... and assembly software, combining all evidence for genes, from expressed sequences, genome assembly sequences, related species protein sequences, and any other, to annotate and score gene constructions. Over-produced constructions are classified by gene evidence for best qualities per "locus", including genome-aligned and gene-transcript aligned (genome-free) locus identification. All software developed for EvidentialGene is publicly available. See project wiki/blog for notes.
    Downloads: 6 This Week
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  • 3
    MANTI

    MANTI

    MANTI - Mastering Advanced N-Termini Interpretation

    MANTI is a one-stop shop N-termini annotation & evaluation solution. MANTI was previously (un)known as muda.pl ahead of v3.7, the project was renamed to MANTI.pl with v3.7 on 2019-06-24. It congregates information from different MaxQuant or DiaNN/MSFragger output files into a master file suitable explicitly for protein neo-termini analyses. The central anchor for the data congregation is the modificationSpecificPeptides.txt or diann-output.pr_matrix.tsv file - additional data is inferred...
    Downloads: 0 This Week
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  • 4
    Interactome  Transcriptome Integration
    The Interactome-Transcriptome Integration (ITI) algorithm allows the analysis of gene expression data by superimposition of a large scale protein-protein interaction data (human interactome) over several gene expression datasets. ITI extracts regions in the interactome with differentiating expression over two conditions. These subnetworks can that be used to build a generalizable and stable genomic signature for genomic/cancer classification.
    Downloads: 0 This Week
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  • 5

    ASGARD

    Metabolic reconstruction from DNA or protein sequences.

    ASGARD is software for metabolic pathway reconstruction, but it can also generate other types of biological sequence annotation (EC and GO numbers, BLAST reports). This program is intended to be run in UNIX-like systems, and supports SGE or PBS.
    Downloads: 0 This Week
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  • 6
    GenSeed-HMM

    GenSeed-HMM

    Progressive assembly tool using DNA, protein or profile HMMs as seeds.

    ... The first seed is provided by the user, and can be a piece of DNA or protein sequence, or an HMM profile, for increased sensitivity. This program depends on BLAST+ or hmmsearch and a number of third-party support tools (EMBOSS' transeq and splitter, bowtie, 454's sfffile and sffinfo). Which tools will be mandatory depends on the kind of seed and assembler used. Assemblers currently supported include CAP3, Newbler, SOAPdenovo, Velvet, and Abyss.
    Downloads: 0 This Week
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  • 7
    MANTI.pl / muda.pl

    MANTI.pl / muda.pl

    muda.pl - MQ unified data assembler

    -------- ATTENTION START: RENAMING muda.pl was renamed to MANTI.pl with v3.7, project development can be tracked on the MANTI project page on sourceforge.net. Old versions remain here for archival purposes. -------- ATTENTION END muda.pl is an evaluation script (written in Perl) without great dependencies. It congregates information from 4 different MaxQuant output files into a master file suitable explicitly for protein neo-termini analyses. The central anchor for the data...
    Downloads: 0 This Week
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  • 8

    FastaTools

    Performs several operations to Fasta protein databases

    FastaTools performs several operations to Fasta protein databases. For more information, you can have a look at the README.md file in the source code tree: https://sourceforge.net/p/lp-csic-uab/fastatools/code/ci/default/tree/README.md Or you can download the Documentation an Tutorial PDF file in the Files section: https://sourceforge.net/projects/fastatools.lp-csic-uab.p/files/FastaTools%20Documentation%20and%20Tutorials.pdf - Gallardo, Ó., Ovelleiro, D., Gay, M., Carrascal, M...
    Downloads: 0 This Week
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  • 9

    JCVI VIGOR

    Viral Genome ORF Reader

    VIGOR (Viral Genome ORF Reader) is a perl application to predict protein sequences encoded in viral genomes. VIGOR determines the protein coding sequences by sequence similarity searching against curated viral protein databases. Please see the wiki to see list of all supported viruses. This work has been funded in whole or part with federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services under...
    Downloads: 0 This Week
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  • 10
    CSBB-v2.1 [CSBB-v3.0 is now available]

    CSBB-v2.1 [CSBB-v3.0 is now available]

    Computational Suite For Bioinformaticians and Biologists

    CSBB is a command line based bioinformatics suite to analyze biological data acquired through varied avenues of biological experiments. CSBB is implemented in Perl, while it also leverages the use of R, java and ruby in background for specific modules. Major focus of CSBB is to allow users from biology and bioinformatics community, to get benefited by performing down-stream analysis tasks while eliminating the need to write programming code. CSBB is currently available on Linux, UNIX and...
    Downloads: 0 This Week
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  • 11

    mfsizes

    Multi-FASTA sequence (DNA or protein) statistics calculator.

    A simple command-line utility to calculate biological sequence (DNA or protein) sizes in a (multi) FASTA file. It gives averages, GC (or methionine) content, N50, N90, N95, number of N's, and total bases, and can also report by codon if requested.
    Downloads: 0 This Week
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  • 12
    CSBB-v2.0

    CSBB-v2.0

    Computational Suite for Bioinformaticians and Biologists

    CSBB is a command line based bioinformatics suite to analyze biological data acquired through varied avenues of biological experiments. CSBB is implemented in Perl, while it also leverages the use of R, java and ruby in background for specific modules. Major focus of CSBB is to allow users from biology and bioinformatics community, to get benefited by performing down-stream analysis tasks while eliminating the need to write programming code. CSBB is currently available on Linux, UNIX and...
    Downloads: 0 This Week
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  • 13
    HitKeeper is a database application for use in BioInformatics. It deals with "hits" (predicted features) on biological sequences (protein, DNA), handles incremental updates effectively, supports taxonomy, and provides original query tools.
    Downloads: 0 This Week
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  • 14

    Hamstr

    A tool for directed ortholog search in ESTs and proteins

    HaMStR has moved to https://github.com/bionf/hamstr where it is now part of the HaMStR-OneSeq package. HaMStR is a profile hidden Markov model based tool for a directed ortholog search in EST or protein sequence data. The program takes a pre-defined core group of orthologous sequences (core orthologs) and a set of sequences from a search taxon as input. HaMStR then combines in a two-step strategy a pHMM based search and a reverse search via BLAST to extend the core ortholog group with novel...
    Downloads: 0 This Week
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  • 15
    Kinannote

    Kinannote

    Protein Kinase Identification and Classification

    Kinannote identifies and classifies protein kinases in a user-provided fasta file using an HMM derived from serine/threonine protein kinases, a position specific scoring matrix derived from the HMM, and comparison with a local version of the curated kinase database from kinase.com. If the user inputs a complete proteome, additional modules evaluate the completeness of the kinome and place it in context with reference kinomes. Kinannote runs on a unix command line and depends on local hmmer 2...
    Downloads: 0 This Week
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  • 16
    Grinder
    Grinder is a versatile open-source bioinformatic tool to create simulated omic shotgun and amplicon sequence libraries for all main sequencing platforms.
    Downloads: 2 This Week
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  • 17
    The Protein Similarity Network

    The Protein Similarity Network

    Human protein similarity network used to predict drug safety.

    This is the protein similarity network - PSIN. Here, the nodes are human proteins and they are linked only if they share considerable sequence similarity. We found that this network is particularly useful to distinguish approved from problematic drug-targets. Here you also find the complete set of programs and datasets we used for this purpose. Free to help further test and develop this project. Your help and expertise are much appreciated ! If you have any questions, please do...
    Downloads: 0 This Week
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  • 18

    SPA

    SPA: a short peptide assembler for metagenomic data

    The metagenomic paradigm offers the opportunity to study protein families, and therefore the metabolic and functional potential, of the constituent microbes in a community. A nucleotide assembly-based strategy does not fare much better since metagenomic assemblies are typically very fragmented and also leave a large fraction of reads unassembled. We present a method for reconstructing complete protein sequences directly from NGS metagenomic data. Our framework is based on a novel Short Peptide...
    Downloads: 3 This Week
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  • 19
    EVidenceModeler (aka EVM) combines ab initio gene predictions and spliced protein and transcript alignments into weighted consensus gene structure predictions.
    Downloads: 0 This Week
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  • 20

    BIRAP

    Bacterial Intergenic Region Analysis Pipeline

    BIRAP (Bacterial Intergenic Region Analysis Pipeline) is an open source, easy to use Perl pipeline that can be used to re-annotate bacterial genomes using experimental data. The tool integrates expression profile derived from RNA-seq and/or proteogenomics, compares it with existing in silico annotation and helps validate annotation, identify novel protein coding regions, putative non-coding RNA as well as help correct er-rors in the existing annotation. The pipeline requires “pileup” output...
    Downloads: 0 This Week
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  • 21

    CIMS

    Crosslinking induced mutation site analysis

    This package includes the scripts to detect statistically reproducible crosslinking induced mutation sites (CIMS) and cross linking induced truncation sites (CITS) from HITS-CLIP data. References: Moore, M.*, Zhang, C.*, Gantman, E.C., Mele, A., Darnell, J.C., Darnell, R.B. 2014. Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis. Nat Protocols, 9:263-293. Zhang,C.†, Darnell, R.B.† 2011. Mapping...
    Downloads: 0 This Week
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  • 22

    DNATweezer

    A suite of BioPerl wrappers for manipulating DNA and protein sequences

    DNATweezer is a suite of Perl scripts for manipulating DNA and proteins sequences. These scripts provide command-line access to the most frequently used BioPerl DNA object methods e.g. reverse-complement and translation of DNA sequences, slicing a sequence alignment, rerooting a phylogenetic tree, and calculating diversity of a population of DNA sequences.
    Downloads: 0 This Week
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  • 23
    MGEScan is a suite of two software tools MGEScan-LTR and MGEScan-non-LTR. MGEScan-LTR is a software that can identify new LTR retrotransposons without relying on a library of known elements. It uses approximate string matching technique and protein domain analysis to detect intact LTR retrotransposons. In addition, it identifies partially deleted or solo LTRs using profile Hidden Markov Models (pHMMs). MGEScan-non-LTR is a software for the identification of non-LTR retrotransposons...
    Downloads: 0 This Week
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  • 24
    FSA is a probabilistic multiple sequence alignment algorithm which uses a "distance-based" approach to aligning homologous protein, RNA or DNA sequences.
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    Downloads: 4 This Week
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  • 25

    Protdraw

    Create portable, flexible domain drawings of protein sequences

    For ProtDraw to work on MacOS Yosemite, you must install a patched Pert Tk. Go to https://github.com/eserte/perl-tk and click the Download zip button. Run the unzip command, cd to the extracted directory and follow the directions in the 'INSTALL' file (using 'sudo' if necessary). ProtDraw creates flexible, easily-interpretable and portable illustrations of the domain structures of input sequences. ProtDraw is accompanied by makeProtDraw, a helper program which runs hmmer3 on a specified...
    Downloads: 0 This Week
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