Search Results for "genome assembly"
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Showing 90 open source projects for "genome assembly"
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FindPlasmids
Find plasmids in microbial genome assembly files
FindPlasmids identifies known plasmids in genome assembly files by using the assembly file to query a local Blast+ database of plasmid sequences. The FindPlasmids package includes executables for Mac OS X, Linux and Windows. Detailed instructions for making the local plasmid database, searching it, and identifying the plasmids are included in the FindPlasmids package. -
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BRIG is a cross-platform (Windows/Mac/Unix) application that can display circular comparisons between a large number of genomes, with a focus on handling genome assembly data. Please cite the BRIG paper if BRIG is used to generate figures for publications: NF Alikhan, NK Petty, NL Ben Zakour, SA Beatson (2011) BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons, BMC Genomics, 12:402. PMID: 21824423
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NGSEP
NGSEP (Next Generation Sequencing Experience Platform)
NGSEP is an integrated framework for analysis of short and long DNA high throughput sequencing reads. The current version provides functionalities for both de-novo and reference guided analysis of sequencing data, including genome assembly, read mapping, variants detection and genotyping and de-novo analysis of data generated from reduced representation protocols. NGSEP also provides modules for analysis of genomic variation databases (VCF files), including functional annotation, filtering, format conversion, comparison, clustering, imputation, introgression analysis and different kinds of statistics. ... -
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GeneMiner2 is a comprehensive toolkit designed for phylogenomic genomics. Its main functionalities include: - Mining single-copy nuclear genes, plastid genes/genomes, and other molecular markers from next-generation sequencing data. - Aligning and trimming multiple molecular markers, constructing concatenated and coalescent-based phylogenetic trees, and calibrating tree time. Reference for GeneMiner2: Yu XY, Tang ZZ, Zhang Z, Song YX, He H, Shi Y, Hou JQ, Yu Y. 2026. GeneMiner2:...
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EvidentialGene
Evidence Directed Gene Construction for Eukaryotes
...The basic Evigene methods involve using available best-of-breed gene prediction and assembly software, combining all evidence for genes, from expressed sequences, genome assembly sequences, related species protein sequences, and any other, to annotate and score gene constructions. Over-produced constructions are classified by gene evidence for best qualities per "locus", including genome-aligned and gene-transcript aligned (genome-free) locus identification. ... -
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GenTreat is a computational pipeline with an intuitive graphical interface, was developed for automated hybrid assembly of prokaryotic genomes, performs assembly using two assemblers, merges the results, and then orders and annotates the assembled genome. Validation using raw reads from 61 organisms demonstrated that is a viable alternative for automated hybrid assembly, eliminating the need for using extensive command lines.
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HipMer
A High performance distributed memory assembler for big genomic data
HipMer is the first end-to-end de novo genome assembler designed for extreme scale analysis via efficient parallelization. The single-genome assembly implementation is a high-performance parallelization and port of the Meraculous assembler (http://jgi.doe.gov/data-and-tools/meraculous/). The MetaHipMer extension is a recent addition to HipMer that is geared to large metagenomes and leverages iterative kmer sizes and a specialized scaffolding algorithm to produce increased contiguity and accuracy in metagenomic assemblies. ... -
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Citrus
Citrus: Editing HiC data for de novo genome assembly
juicer and 3D-DNA are two tools that re-arranges HiC data (xxx.hic format) and splits/re-orders super-scaffold data (xxx.assembly) to improve de novo genome assembly. Juicebox was specifically designed to tune or adjust genomic sequences based on HiC data. However, the current Juicebox version does not have a function to save updated HiC data and to summarize chromosome sequences. Thus, we created Citrus which can edit super-scaffolds according to chromatin conformation data captured in xxx.hic. ... -
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A fully developed set of DNA sequence assembly (Gap4 and Gap5), editing and analysis tools (Spin) for Unix, Linux, MacOSX and MS Windows.
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lemonade_assemble
Specialized sequence assembly tools
Assorted tools for: 1. Assembly of pooled BACs from PacBIO reads. 2. Polymorphic genome assembly 3. Processing of Trinity transcriptomes 4. Modified versions of other people's code used in any of the above. 5. Fasta processing and miscellaneous programs and scripts. Documentation is rudimentary or nonexistant. -
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Phusion2
The genome assembly pipeline based on read clustering
Phusion2 is a pipeline for de novo genome assembly using NGS data. It is based upon a strategy called read clustering. Starting with kmer frequency analysis, this allows for a reasonable selection of the kmer sizes. K-tuples from raw reads are merged and sorted into a table so that multiple occurring kmer words shared by different reads can be linked. A relation matrix is used to record the shared kmer words among all the reads. -
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ImproveAssembly
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206
The availability of biological information in public databases has increased exponentially. To ensure the accuracy of this information, researchers have adopted several methods and refinements to avoid the dissemination of incorrect information. However, manual curation ensures and enriches biological information. Additionally, the genomic finishing process is complex, resulting in increased deposition of drafts genomes. This introduces bias in other omics analyses because incomplete... -
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MitoZ: A toolkit for mitochondrial genome assembly, annotation and visualization. see https://github.com/linzhi2013/MitoZ
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Meraculous-2D
Eukaryotic Genome Assembler
...The assembly is driven by a perl pipeline which performs data fragmentation and load balancing, as well as submission and monitoring of multiple task arrays on a GE/SLURM-type cluster or a standalone multi-core server. Manuscripts in submission: https://arxiv.org/abs/1703.09852 https://arxiv.org/abs/1608 -
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Genobuntu
Genobuntu Package for Next Generation Sequencing
...Therefore, Genobuntu offers a well-tailored environment for both novices and experts working in the field of genome assembly. -
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GMcloser
Closing the gaps in scaffolds with preassembled contigs
...An accompanied package, GMvalue, is a tool to determine misassembly sites in contigs and scaffolds. Unlike other related tools, GMvalue can define misassembly categories with several options, and can be applied to assemblies of a large size genome. By using the -e option, GMvalue also generates error-free assemblies by splitting or correcting misassembles. -
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Genome Downloader
Downloads genome data from NCBI based on search terms.
GenomeDownloader is a command-line Perl program to download genomic data (using wget) from NCBI. It has been recently (2017-10) completely rewritten to work with the "new" data organization structure at NCBI. Assembly completion level (i.e., Contig, Scaffold, Chromosome or Complete Genome) can also be selected as a criterion for downloading data. Genomic data can be downloaded from all organisms belonging to a certain taxon (e.g., Mammalia or 40674), and downloads can be limited to certain kinds of files (e.g., faa or faa,gbff etc.). Search terms can also be used to further limit results. ... -
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GAVGA
A Genetic Algorithm for Viral Genome Assembly
GAVGA is a Genetic Algorithm for Viral Genome Assembly. It can be used in the assembly of small genomes, like viral ones. -
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BWA is a program for aligning sequencing reads against a large reference genome (e.g. human genome). It has two major components, one for read shorter than 150bp and the other for longer reads.
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Basejumper is a viewer for genome assembly data. It is designed to read in assembled DNA sequences in ACE format from massively parallel (or “next-generation”) sequencing experiments (Illumina/Solexa and Roche/454).
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wgssat_nbfgr
WGSSAT: SSR Annotation Pipeline
WGSSAT provides a Graphical User Interface pipeline to mine and characterize SSR from Whole genome data. This pipeline integrates prediction of genes, ncRNA, repeats and SSR from whole genome assembly and mapping of these predicted SSR on to the genome (classified according to genes, ncRNA, repeats, exonic and intronic region) along with primer designing and mining of cross-species amplification markers. The mining of SSRs from whole genome provides valuable information on the abundance of SSRs in various genomic regions and will also facilitate the development of markers for genetic analysis and related applications, such as marker-assisted breeding and linkage mapping. -
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GATOOL - Genome Assembly Tool
The tool allows to perform a bacterial genome assembly.
GATOOL is a web interface whichs integrates several tools, with the purpose of to do a genome assembly task and provide to the users a nice and real experience. and a very fast way to genomes assembly. -
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A project made by Khalid Bashir. It's simple linux program which evaultes the genome assembly with high speed and accuracy. Please read instuctions.md [Options] Argument 1 -> Name of the input fasta/fastaq file Argument 2 -> Sequence Limit (optional)(Default: 999999999) Argument 3 -> Usable scaffold length (optional)(Default: 2500) Argument 4 -> Number of Nucliotide to spit into contigs (optional)(Default: 25) Argument 5 -> Genome size (optional)
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QSdpR
Viral Quasispecies Reconstruction software based on QSdpR algorithm
This is a viral quasispecies reconstruction software for quasispecies assembly problem on mRNA viruses, which is based on a correlation clustering approach and uses semidefinite optimization framework. The software accepts a reference genome, a NGS read set aligned to this reference and set of SNP locations in the form of a vcf file and outputs an optimal set of reconstructed species genomes which describes the underlying viral population.
