Showing 428 open source projects for "rna-seq"

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  • 1

    spark-msna

    Algorithm on Spark for aligning multiple similar DNA/RNA sequences

    The algorithm uses suffix tree for identifying common substrings and uses a modified Needleman-Wunsch algorithm for pairwise alignments. In order to improve the efficiency of pairwise alignments, an unsupervised learning based on clustering technique is used to create a knowledge base to guide them.
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  • 2
    We introduce a nonparametric Bayesian clustering method for inhomogeneous Poisson processes to detect heterogeneous binding patterns of multiple proteins including transcription factors. The estimated protein clusters form regulatory modules in different chromatin states, which help explain how proteins work together in regulating gene expression. We applied this approach on ChIP-seq data for mouse neural stem cells containing 21 proteins and observed different groups or modules of proteins...
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  • 3
    CSBB-v2.1 [CSBB-v3.0 is now available]

    CSBB-v2.1 [CSBB-v3.0 is now available]

    Computational Suite For Bioinformaticians and Biologists

    ... and Windows platforms. Currently CSBB provides 17 modules focused on analytical tasks like normalization, visualization, statistics, RNA-SEQ etc.
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  • 4
    CSBB-v3.0

    CSBB-v3.0

    CSBB - Computational Suite for Bioinformaticians and Biologists

    CSBB is a command line-based bioinformatics suite to analyze biological data acquired through varied avenues of biological experiments. CSBB is implemented in Perl, while it also leverages the use of R, java, python and ruby in background for specific modules. Major focus of CSBB is to allow users from biology and bioinformatics community, to get benefited by performing down-stream analysis tasks while eliminating the need to write programming code. CSBB is currently available on Linux,...
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  • 5

    Genobuntu

    Genobuntu Package for Next Generation Sequencing

    Genobuntu is a software package containing more than 70 software and packages oriented towards NGS. In its current version, Genobuntu supports pre assembly tools, genome assemblers as well as post assembly tools. Commonly used biological software and example script files for different assembly pipelines have also been provided, where the example script files can be updated to suit one’s experimental needs. Genobuntu attempts to reduce the amount of time and energy needed to build ...
    Downloads: 1 This Week
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  • 6

    PPLine

    SNP calling, annotation and gene/transcripts expression quantification

    PPLine is a Python-based suite aimed to process raw RNA-seq or Exome-seq data. PPLine provides: - read mapping (STAR/Tophat2/bowtie/bowtie2), including novel splice junsctions discovery - gene and transcript expression estimation (HTSeq-count/Cufflinks) - SNP calling with BQSR and indel realignment (samtools/GATK) - variant annotation (Annovar) - novel transcripts discovery (Cufflinks) - predicting proteotypic peptides and creating ref/alt proteins fasta-database - integration of the results
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  • 7

    cash-program

    Comprehensive alternative splicing hunting

      CASH (Comprehensive alternative splicing hunting) is visualized and user-friendly software that aims to self-construct AS (alternative splicing) sites and detect differential AS events between samples of RNA-Seq data. CASH consists of two major stages: SpliceCons (Splice site Construction) and SpliceDiff (differential AS detection). By comprehensively reconstructing AS sites from RNA-seq data, SpliceCons increases the recognition of AS events considerably and subsequently, SpliceDiff uses two...
    Downloads: 1 This Week
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  • 8

    lr2rmats

    Long read to rMATS

    lr2rmats is a Snakemake-based light-weight pipeline which is designed to utilize both third-generation long-read and second-generation short-read RNA-seq data to generate an enhanced gene annotation file. The newly generated annotation file could be provided to rMATS for differential alternative splicing analysis. More information can be found at https://sourceforge.net/p/lr2rmats/wiki/Home/
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  • 9
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  • 10

    DualTranscriptDiscovery

    Transcript-discovery approach for gene feature delimitation by RNA-seq

    This project contains Python scripts usable for a dual transcript-discovery approach that improves the delimitation of gene features from RNA-seq data in the chicken model. Documentation: http://bio.biologists.org/content/biolopen/suppl/2018/01/17/bio.028498.DC1/BIO028498supp.pdf Citation: Orgeur M., Martens M., Börno S. T., Timmermann B., Duprez D. and Stricker S. (2018). A dual transcript-discovery approach to improve the delimitation of gene features from RNA-seq data in the chicken model...
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  • 11

    BisSNP

    Bisulfite-seq/NOMe-seq SNPs & cytosine methylation caller

    Now in Github: https://github.com/dnaase/Bis-tools/tree/master/Bis-SNP BisSNP is a package based on the Genome Analysis Toolkit (GATK) map-reduce framework for genotyping in bisulfite treated massively parallel sequencing (Bisulfite-seq, NOMe-seq and RRBS) on Illumina platform. It uses bayesian inference with either manually specified or automatically estimated methylation probabilities of different cytosine context(not only CpG, CHH, CHG in Bisulfite-seq, but also GCH et.al. in other...
    Downloads: 2 This Week
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  • 12
    A collaborative platform for non-protein-coding RNA annotation.
    Downloads: 0 This Week
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  • 13

    MethyMer

    Design of specific primer combinations for bisulfite sequencing

    ...) and gene expression (RNA-Seq) data, as well as methylation-expression correlation analysis results for 20 human cancer types. ENCODE genome regions annotation data are also integrated in MethyMer
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  • 14

    RNAfdl

    RNA force directed layout

    RNAfdl is a highly flexible tool for drawing RNA secondary structures. Secondary structures can be visualized as classical secondary structure plot, circle plot, linear plot or mountain plot. RNAfdl allows manual editing and several drawing styles, as well as a fully automated conjugate gradients minimization approach to draw more complex structures without user interaction. In addition, RNAfdl allows you to incorporate non-canonical base pairs into drawings.
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  • 15
    gogadget

    gogadget

    A toolbox for interpretation and visualization of RNA-seq GO analysis

    gogadget is an R package, and can help with the visualization and interpretation of GO enrichment analysis of RNA-seq data. It is developed especially for the use in combination with goseq. The functions that are available in this package are extensively described in the user's guide. To install the package download the "gogadget_2.1.tar.gz" file, open R and install with the following line: install.packages( "C:/your/directory/gogadget_2.1.tar.gz", repos = NULL, type="source") The package...
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  • 16

    dnase2tf_R

    dnase2tf finds footprint candidates from the DNase-I seq data

    dnase2tf finds footprint candidates from the DNase-I seq data (given by datafilepath) on the user specified regions of interest (given by hotspotfilename). Mappability file location (mapfiledir) and the filename for the output file are also required.
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  • 17
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  • 18
    wgssat_nbfgr

    wgssat_nbfgr

    WGSSAT: SSR Annotation Pipeline

    WGSSAT provides a Graphical User Interface pipeline to mine and characterize SSR from Whole genome data. This pipeline integrates prediction of genes, ncRNA, repeats and SSR from whole genome assembly and mapping of these predicted SSR on to the genome (classified according to genes, ncRNA, repeats, exonic and intronic region) along with primer designing and mining of cross-species amplification markers. The mining of SSRs from whole genome provides valuable information on the abundance of...
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  • 19
    siFi21

    siFi21

    si-Fi is a Software for RNAi (RNA interference) off-target prediction.

    si-Fi is a Software for RNAi (RNA interference) off-target prediction The software is designed for checking long-double stranded RNAi constructs for target specificity and silencing efficiency. It can be used also to select sequence regions suitable for designing RNAi constructs. The program provides clear tabular and graphical outputs.
    Downloads: 13 This Week
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  • 20

    CRISPR-offinder-v1-2

    A CRISPR tool for user-defined protospacer adjacent motif

    CRISPR/Cas system undoubtedly holds great potential for genome editing. Target site cleavage by CRISPR technology requires a protospacer adjacent motif (PAM) immediately downstream or upstream of the protospacer element to which the sgRNA binds. However, Cas9 from different types of bacteria or variant recognizes different PAM sequences. To meet the needs of different CRISPR system with specific and efficient sgRNA design, CRISPR-offinder was developed. Given an input FASTA file of the...
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  • 21

    meerkat.sh

    script of SV calling in Exome-seq

    meerkat.sh is a shell script to run Meerkat for SV detection in Exome-seq. The script accepts single BAM or paired tumor-normal BAMs.
    Downloads: 1 This Week
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  • 22
    wechat4u.js

    wechat4u.js

    JavaScript implementation of WeChat wechat web interface

    ... avatar base64 data is no longer stored in the bot.user object. Rremove the example directory. Fix some data in Contact and Message data is not enumerable. Pass the complete Error object to the upper-level code, and put the original Chinese error description in err.tips. The bot.getContact(Seq) method adds the Seq parameter to support incremental acquisition of complete contacts.
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  • 23
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  • 24
    CSBB-v2.0

    CSBB-v2.0

    Computational Suite for Bioinformaticians and Biologists

    ... and Windows platforms. Currently CSBB provides 16 modules focused on analytical tasks like normalization, visualization, statistics, RNA-SEQ etc.
    Downloads: 0 This Week
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  • 25
    faif

    faif

    C++ header only library with AI and bioinformatics algorithms

    C++ header only library, small and fast; Naive Bayesian Classifier, Decision Tree Classifier (ID3), DNA/RNA nucleotide second structure predictor, timeseries management, timeseries prediction, generic Evolutionary Algorithm, generic Hill Climbing algorithm and others.
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