Alternatives to Photo51
Compare Photo51 alternatives for your business or organization using the curated list below. SourceForge ranks the best alternatives to Photo51 in 2026. Compare features, ratings, user reviews, pricing, and more from Photo51 competitors and alternatives in order to make an informed decision for your business.
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Claude Mythos 5.1
Anthropic
Claude Mythos 5.1 is Anthropic’s newest Mythos-class model, designed for advanced cybersecurity, biology, scientific research, coding, and long-running knowledge work. It is the same underlying model as Claude Fable 5.1 but uses different safeguards: Fable 5.1 is generally available, while Mythos 5.1 is restricted to trusted access programs with safeguards specifically designed for cybersecurity and life sciences research. The model sets a new performance frontier for agentic coding and demonstrates the strongest cyber capabilities of any Anthropic model released to date. In scientific research, Mythos 5.1 can work with specialized tools and complex workflows across molecular design, computational biology, and other technical domains. In Anthropic’s experiments, it designed high-affinity protein binders across multiple targets and achieved its strongest measured hit rate to date. It also optimized seven open-source protein and genomics deep learning models. -
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Claude Mythos 5
Anthropic
Claude Mythos 5 is Anthropic’s most advanced restricted-access AI model, designed for trusted cyberdefenders, infrastructure providers, and select research organizations. It uses the same underlying model as Claude Fable 5 but provides lifted safeguards in approved areas for specialized high-trust use cases. The model delivers exceptional capabilities in cybersecurity, software engineering, scientific research, long-context reasoning, vision, and autonomous task execution. Anthropic initially deployed Claude Mythos 5 through Project Glasswing in collaboration with the U.S. government to help protect critical software and infrastructure. The model also shows strong potential in life sciences, including protein design, molecular biology hypothesis generation, and genomics research. Claude Mythos 5 is built for organizations that need frontier AI capabilities under controlled, trusted-access conditions.Starting Price: $10 per 1 million (input) -
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SnapGene
SnapGene
Accurately design and simulate cloning procedures. Test complicated projects, catch errors before they happen, and obtain the right constructs the first time. Cloning is easier when you can see what you are doing. The intuitive interface offers you unparalleled visibility into your work, simplifying often complex tasks. SnapGene automates documentation, so you don’t have to. See and share every sequence edit and cloning procedure that led to your final plasmid. Improve your core molecular biology procedures, and improve your results. Master SnapGene and key concepts in cloning with our new online learning center, SnapGene Academy. Containing over 50 video tutorials taught by scientific experts, SnapGene Academy helps you advance your skills across multiple molecular biology courses. SnapGene 7.2 provides a new visualization of primer homodimer structures and enhancements to file management, allowing tabs to be organized in multiple windows using drag and drop.Starting Price: $295 per year -
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Evo 2
Arc Institute
Evo 2 is a genomic foundation model capable of generalist prediction and design tasks across DNA, RNA, and proteins. It utilizes a frontier deep learning architecture to model biological sequences at single-nucleotide resolution, achieving near-linear scaling of compute and memory relative to context length. Trained with 40 billion parameters and a 1 megabase context length, Evo 2 processes over 9 trillion nucleotides from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function prediction across multiple biological modalities, including DNA, RNA, and proteins, and to generate novel sequences with plausible genomic architecture. The model's capabilities have been demonstrated in tasks such as designing functional CRISPR systems and predicting disease-causing mutations in human genes. Evo 2 is publicly accessible via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework. -
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Evo Designer
Arc Institute
Evo Designer is an advanced tool developed by the Arc Institute, leveraging the capabilities of the Evo 2 genomic foundation model to facilitate DNA sequence generation and analysis. This platform enables users to input nucleotide sequences or specify organisms, prompting the model to generate corresponding DNA sequences. It provides comprehensive annotations of coding regions and, for prokaryotic sequences, offers 3D protein visualizations utilizing ESMFold. Additionally, Evo Designer evaluates sequences by scoring their perplexity and per-nucleotide entropy, assisting researchers in assessing sequence complexity and variability. The underlying Evo 2 model is trained on over 9 trillion nucleotides from a diverse array of prokaryotic and eukaryotic genomes, employing a deep learning architecture that models biological sequences at single-nucleotide resolution with a context window extending up to 1 million tokens. -
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Geneious
Geneious
Geneious Prime makes bioinformatics accessible by transforming raw data into visualizations that make sequence analysis intuitive and user-friendly. Simple sequence assembly and easy editing of contigs. Automatic annotation for gene prediction, motifs, translation, and variant calling. Genotype microsatellite traces with automated ladder fitting and peak calling and generates tables of alleles. Beautiful visualizations of annotated genomes and assemblies are displayed in a highly customizable sequence view. Powerful SNP variants analysis, simple RNA-Seq expression analysis, and amplicon metagenomics. Design and test PCR and sequencing primers and create your own searchable primer database. Geneious Biologics is a flexible, scalable, and secure way to streamline your antibody analysis workflows, create high-quality libraries and select the optimal therapeutic candidates.Starting Price: $1,280 per year -
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Partek Flow
Partek
Partek bioinformatics software delivers powerful statistical and visualization tools in an easy-to-use interface. Researchers of all skill levels are empowered to explore genomic data quicker and easier than ever before. We turn data into discovery®. Pre-installed workflows and pipelines in our intuitive point-and-click interface make sophisticated NGS and array analysis attainable for any scientist. Custom and public statistical algorithms work in concert to easily and precisely distill NGS data into biological insights. Genome browser, Venn diagrams, heat maps, and other interactive visualizations reveal the biology of your next-generation sequencing and array data in brilliant color. Our Ph.D. scientists are always just a phone call away and ready to help with your NGS analysis any time you have questions. Designed specifically for the compute-intensive needs of next-generation sequencing applications with flexible installation and user management options. -
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Biohub
Biohub
Biohub is an open platform for building on the world model of protein biology. It provides access to the ESM family of models, including ESMC, ESMFold2, and ESM3, along with interactive tools and developer resources for protein science research. ESMC is a state-of-the-art protein language model trained on billions of evolutionary sequences, building representations that capture fundamental mechanisms of protein structure and function. It powers functional analysis, structure prediction, protein design, and the exploration of evolutionary relationships between proteins. ESMFold2 predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequence, with optional multiple sequence alignment input for enhanced accuracy on challenging targets. ESM3 jointly models sequence, structure, and function, enabling controllable generation of novel proteins by conditioning on any combination of these modalities. -
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HyperProtein
Hypercube
HyperProtein is Hypercube, Inc.'s new product focusing on the computational science associated with protein sequences. The product includes the analysis of one-dimensional protein sequences as well as the analysis of consequent three-dimensional protein structures. In particular, the relationship between sequence and structure is a fundamental facet of the product. Unlike individual software programs that provide capability for some aspect of protein sequence or structure, such as sequence alignment, HyperProtein puts together a multitude of Bioinformatics and Molecular Modeling tools related to the science that initiates with a protein sequence. -
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SeqOne
SeqOne
SeqOne is an AI-powered genomic analysis platform designed to help molecular laboratories, clinical teams, biologists, and geneticists transform complex next-generation sequencing data into fast, precise, and actionable clinical insights to support personalized medicine diagnostics. It streamlines end-to-end genomic workflows, from raw sequencing files to variant interpretation and reporting, by automating routine pipeline tasks, integrating seamlessly with lab systems, and using advanced AI models such as DiagAI to rank and highlight disease-relevant variants with explainable scores, reducing manual effort and turnaround time. SeqOne supports germline and somatic analyses across applications, including oncology, rare and inherited diseases, and infectious disease detection, combining premium annotation databases and standardized interpretation guidelines to ensure clinical-grade accuracy within an intuitive user interface that scales via secure cloud. -
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Sapio ELN
Sapio Sciences
Sapio ELN is an electronic lab notebook that flexes to the needs of every scientific experiment by combining a built-in AI assistant, science-aware tools, no-code configurability, and powerful data integration and visualization into one unified platform. Its ELaiN chat assistant lets scientists create and configure experiments, manage consumables, integrate and query data, visualize results, optimize DNA sequences, and even generate custom code, all via natural-language conversation. The ELN includes an advanced molecular biology toolkit (CRISPR design, plasmid and compound design, PCR primer design, vector modification, genome browser), reusable experiment templates, free-form note taking, instrument integrations, real-time collaboration, and built-in statistical calculations. Science-aware searching lets users find structured and unstructured data, including substructure and similarity compound queries, and instantly generate interactive, scientific visualizations without SQL. -
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XetaBase
Zetta Genomics
The unique XetaBase platform simplifies tertiary analysis, aggregating, indexing, and enriching secondary genomic data, enabling continual re-interpretation to unlock research and clinical insight. XetaBase accelerates data management and the cost-effective application of genomic data in the lab and clinic. XetaBase encompasses genomic scale, the greater the volume and complexity, the greater the insight and outcomes. XetaBase is a genomic-native technology, built on the open-source, OpenCB software platform to meet the scale, speed, and re-interpretation demands of genomic medicine. Zetta Genomics delivers genomic data management fit for the precision medicine age. XetaBase is a completely novel solution to the challenges of genomic data. It sweeps away obsolete flat file approaches to bring meaningful and actionable genomic data into the lab and the clinic. XetaBase empowers continual re-interpretation while scaling seamlessly as databases grow to encompass genome sequences. -
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Illumina DRAGEN Secondary Analysis
Illumina
The Illumina DRAGEN Secondary Analysis provides accurate, comprehensive, and efficient analysis of next-generation sequencing data. Graph reference genome and machine learning driving unprecedented accuracy. Provides ultra-efficient workflow; can fully process a 34x whole human genome in ~30 minutes with DRAGEN server v4. Furthers ultra-efficient workflow by reducing FASTQ file sizes up to 5×. Analyzes next-generation sequencing (NGS) data from whole genomes, exomes, methylomes, and transcriptomes. Available on platform of choice and scalable based on needs. DRAGEN analysis leads in accuracy for germline and somatic variant calling demonstrated in industry challenges from precisionFDA. DRAGEN analysis enables labs of all sizes and disciplines to do more with their genomic data. DRAGEN analysis uses highly reconfigurable field-programmable gate array technology (FPGA) to provide hardware-accelerated implementations of genomic analysis algorithms. -
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MEGA
MEGA
MEGA (Molecular Evolutionary Genetics Analysis) is a powerful and user-friendly software suite designed for analyzing DNA and protein sequence data from species and populations. It facilitates both automatic and manual sequence alignment, phylogenetic tree inference, and evolutionary hypothesis testing. MEGA supports a variety of statistical methods including maximum likelihood, Bayesian inference, and ordinary least squares, making it an essential tool for comparative sequence analysis and understanding molecular evolution. MEGA offers advanced features such as real-time caption generation to help explain the results and methods used in analysis and the maximum composite likelihood method for estimating evolutionary distances. The software is equipped with robust visual tools like the alignment/trace editor and tree explorer and supports multi-threading for efficient processing. MEGA can be run on multiple operating systems, including Windows, Linux, and macOS.Starting Price: Free -
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Genome Computer
Genome Computer
Genome Computer turns your genetic data into a portable, AI-ready .genome bundle you can download, keep, self-host, and explore with Genome Intelligence, Codex, Claude Code, Cursor, or any compatible tool. The open format restructures the same underlying data found in a VCF into a structured, queryable bundle, with variants stored in fast columnar tables alongside trait associations, supporting research, gene-level context, polygenic scores, pharmacogenomics, and clear provenance. Whole-genome sequencing orders are built from gVCF data, preserving both detected variants and confidently sequenced regions where no variant was found, while FASTQ files are available on request. Existing VCF or TXT files from other providers can also be converted, imputed where needed, annotated, scored, and prepared for AI interpretation. Genome Intelligence lets you ask questions grounded in your actual genetic data, compare new research with your genotypes, and explore genetics.Starting Price: $15 per month -
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QIAGEN CLC Genomics Workbench
QIAGEN Digital Insights
QIAGEN CLC Genomics Workbench is a powerful solution that works for everyone, no matter the workflow. Cutting-edge technology and unique features and algorithms widely used by scientific leaders in industry and academia make it easy to overcome challenges associated with data analysis. User-friendly bioinformatics software solutions allow for comprehensive analysis of your NGS data, including de novo assembly of whole genomes and transcriptomes, resequencing analysis (WGS, WES and targeted panel support), variant calling, RNA-seq, ChIP-seq and DNA methylation (bisulfite sequencing analysis). Analyze your RNA-seq and small RNA (miRNA, lncRNA) data with easy-to-use transcriptomics workflows for differential expression analysis at gene and transcript levels. QIAGEN CLC Genomics Workbench is developed to support a wide range of NGS bioinformatics applications. -
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GPT-Rosalind
OpenAI
GPT-Rosalind is a purpose-built frontier reasoning model developed by OpenAI to accelerate scientific research across biology, drug discovery, and translational medicine. It is designed specifically for life sciences workflows, where researchers must navigate large volumes of literature, experimental data, and specialized databases to generate and validate new ideas. It combines deep domain understanding in areas such as chemistry, genomics, protein engineering, and disease biology with advanced tool-use capabilities, allowing it to interact with scientific databases, analyze experimental outputs, and support complex, multi-step reasoning tasks. It can assist with evidence synthesis, hypothesis generation, literature review, sequence interpretation, and experimental planning, helping scientists move faster from raw data to actionable insights. GPT-Rosalind transforms complex, time-intensive research processes into more efficient AI-assisted workflows. -
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GenomeBrowse
Golden Helix
This free tool delivers stunning visualizations of your genomic data that give you the power to see what is occurring at each base pair in your samples. GenomeBrowse runs as a native desktop application on your computer. No longer do you have to sacrifice speed and interface quality to obtain a consistent cross-platform experience. It was developed with performance in mind to deliver a faster and more fluid browsing experience than any other genome browser available. GenomeBrowse is also integrated into the powerful Golden Helix VarSeq variant annotation and interpretation platform. If you love the visualization experience of GenomeBrowse, check out VarSeq for filtering, annotating, and analyzing your data before utilizing the same visualization interface. GB can display all your alignment data. Looking at all your samples in one view can help you spot contextually relevant findings.Starting Price: Free -
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Geneyx
Geneyx
Geneyx Analysis is a comprehensive solution for next-generation sequencing (NGS) data that can scale the process of FASTQ to clinical reports for hospital and commercial labs. This advanced platform integrates machine learning and AI-based features to identify novel biomedical insights, while also improving diagnostic yields and turnaround times. By providing a fully transparent and intuitive solution, Geneyx Analysis enables clinicians and researchers to have complete control over data analysis and alleviates the complexities of regulating in-house bioinformatics pipelines. Protocols can be fully customized to accommodate gene panels, exomes, and genomes, and our comprehensive annotation engine supports the analysis of all genetic variants including structural and copy number variations as well as regulatory elements. Together, Geneyx Analysis automates the diagnostic process from sequencer to report, while creating a comprehensive resource for novel variant discovery. -
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ESMC
Biohub
ESMC is the latest in the ESM family of protein language models, establishing a new frontier in representation learning for protein biology. Trained on billions of evolutionary sequences, it learns representations that reflect a mechanistic reduction of protein structure and function. The model is built on a transformer architecture, supports sequences as its core modality, and is trained on up to 6 billion proteins. ESMC is designed for protein science research, including structure prediction, function annotation, protein design, and understanding evolutionary relationships between proteins. It can generate novel proteins from partial sequence, structure, or functional constraints, helping researchers explore new possibilities in protein design and biological discovery. The Biohub Platform provides access to ESMC through the API and the ESM Python package, with quickstart resources for installing the package, creating an API key, connecting to the platform.Starting Price: Free -
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VarSeq
Golden Helix
Simple, fast, and repeatable variant analysis software for gene panels, exomes, and whole genomes. VarSeq is an intuitive, integrated software solution for tertiary analysis. With VarSeq you can automate your workflows and analyze variants for gene panels, exomes, and whole genomes. Understanding genomic data has never been easier thanks to our software. VarSeq software provides a powerful filtering and annotation engine to sift through large variant data sets. Using a chain of filters, you can quickly narrow your list of variants down to those that are most likely to be of interest. After determining the parameters that work well for your analysis, you can save the state of your filters so that you can easily apply the same analysis to another dataset. The same automated workflow can be used for each batch of samples, making VarSeq an ideal solution for high-throughput environments. Real-time filtering gives you the power to quickly prototype and tune analysis workflows. -
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Universal Analysis Software (UAS) provides a platform for analyzing and managing forensic genomic data, simplifying complex bioinformatics. The UAS is an all-inclusive solution, containing analysis modules supporting all current ForenSeq workflows including ForenSeq MainstAY, ForenSeq Kintelligence, ForenSeq DNA Signature Prep, ForenSeq mtDNA Whole Genome, and ForenSeq mtDNA Control Region. UAS rapidly generates FASTQ files, performs alignment, and calls forensically relevant variants from NGS data. Extensive testing backs highly reliable variant calls to deliver accurate results in a user-friendly package with no per-seat licenses. Designed specifically for forensic analysts, UAS streamlines handling of base-by-base sequence information and contains a range of features to enable everything from efficient review of everyday STR profiles to detailed analysis of the most challenging samples.
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NVIDIA Parabricks
NVIDIA
NVIDIA® Parabricks® is the only GPU-accelerated suite of genomic analysis applications that delivers fast and accurate analysis of genomes and exomes for sequencing centers, clinical teams, genomics researchers, and high-throughput sequencing instrument developers. NVIDIA Parabricks provides GPU-accelerated versions of tools used every day by computational biologists and bioinformaticians—enabling significantly faster runtimes, workflow scalability, and lower compute costs. From FastQ to Variant Call Format (VCF), NVIDIA Parabricks accelerates runtimes across a series of hardware configurations with NVIDIA A100 Tensor Core GPUs. Genomic researchers can experience acceleration across every step of their analysis workflows, from alignment to sorting to variant calling. When more GPUs are used, a near-linear scaling in compute time is observed compared to CPU-only systems, allowing up to 107X acceleration. -
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Genome Analysis Toolkit (GATK)
Broad Institute
Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. The GATK is the industry standard for identifying SNPs and indels in germline DNA and RNAseq data. Its scope is now expanding to include somatic short variant calling and to tackle copy number (CNV) and structural variation (SV). In addition to the variant callers themselves, the GATK also includes many utilities to perform related tasks such as processing and quality control of high-throughput sequencing data and bundles the popular Picard toolkit. These tools were primarily designed to process exomes and whole genomes generated with Illumina sequencing technology, but they can be adapted to handle a variety of other technologies and experimental designs.Starting Price: Free -
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GenomeStudio
Illumina
Visualize and analyze data generated on Illumina array platforms with GenomeStudio Software. This powerful solution supports the genotyping analysis of microarray data. Performance-optimized tools and a user-friendly graphical interface enable you to convert data into meaningful results quickly and easily. Analyze SNP and CNV data across 5 million markers and probes. Detect sample outliers. Analyze differentially expressed genes across different genomes. Profile miRNA expression. Combine mRNA and microRNA data in a single project. Detect cytosine methylation at single-base resolution. Identify methylation signatures across the entire genome. At Illumina, our goal is to apply innovative technologies to the analysis of genetic variation and function, making studies possible that were not even imaginable just a few years ago. It is mission critical for us to deliver innovative, flexible, and scalable solutions to meet the needs of our customers. -
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CryoTrack
CryoTrack
CryoTrackIMS is a complete software package - ideal for molecular biology, cell banks, cellular biology, clinical samples, biorepository, biobanking, biochemistry, immunology and protein labs, high-throughput screening, QA, IVF labs and core labs and facilities. Create any box, plate or pie configuration - select rows and columns or select a Pie configuration - your box is created in seconds ready to input data. Inventory of valuable biological samples and specimen is critical for basic research and biotech business. Keeping track of large numbers and types of samples (DNA, RNA, plasmids, clones, proteins, peptides, probes, antibodies, enzymes, specimen, tissues, cell lines and more) and where they are and their precise location is a nightmare and daunting task for many that cost a great deal not only in monetary terms but also leads to frustrations and time loss. CryoTrack offers a complete solution for individual labs in universities, clinics, biotech and pharmaceutical companies. -
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Eidogen-Sertanty Target Informatics Platform (TIP)
Eidogen-Sertanty
Eidogen-Sertanty's Target Informatics Platform (TIP) is the world's first structural informatics system and knowledgebase that enables researchers with the ability to interrogate the druggable genome from a structural perspective. TIP amplifies the rapidly expanding body of experimental protein structure information and transforms structure-based drug discovery from a low-throughput, data-scarce discipline into a high-throughput, data-rich science. Designed to help bridge the knowledge gap between bioinformatics and cheminformatics, TIP supplies drug discovery researchers with a knowledge base of information that is both distinct from and highly complementary to information furnished by existing bio- and cheminformatics platforms. TIP's seamless integration of structural data management technology with unique target-to-lead calculation and analysis capabilities enhances all stages of the discovery pipeline. -
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Illumina Connected Analytics
Illumina
Store, archive, manage, and collaborate on multi-omic datasets. Illumina Connected Analytics is a secure genomic data platform to operationalize informatics and drive scientific insights. Easily import, build, and edit workflows with tools like CWL and Nextflow. Leverage DRAGEN bioinformatics pipelines. Organize data in a secure workspace and share it globally in a compliant manner. Keep your data in your cloud environment while using our platform. Visualize and interpret your data with a flexible analysis environment, including JupyterLab Notebooks. Aggregate, query, and analyze sample and population data in a scalable data warehouse. Scale analysis operations by building, validating, automating, and deploying informatics pipelines. Reduce the time required to analyze genomic data, when swift results can be a critical factor. Enable comprehensive profiling to identify novel drug targets and drug response biomarkers. Flow data seamlessly from Illumina sequencing systems. -
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BaseSpace Sequence Hub
Illumina
Data management and simplified bioinformatics for labs getting started and for rapidly scaling next-generation sequencing (NGS) operations. As a key component of the BaseSpace Suite, BaseSpace Sequence Hub is a direct extension of your Illumina instruments. Encrypted data flow from the instrument into BaseSpace Sequence Hub, enabling you to manage and analyze your data easily with a curated set of analysis apps. BaseSpace Sequence Hub is powered by Amazon Web Services (AWS). Offers a security-first environment. Enables you to set up runs and monitor instrument run quality. Promotes efficiency by converting sequencing data to a standard format and streaming directly to the cloud. Provides access to computing resources without the capital expenditure of in-house infrastructure. Increases organizational productivity with easy access to a multitude of genomic analysis apps (provided by you, Illumina, or third parties). -
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g.nome
Almaden Genomics
g.nome, a cloud-native platform that delivers streamlined, scalable, and interoperable workflows for next-generation sequencing analysis. g.nome provides a low-code/no-code pipeline build. With pre-built workflows and toolkits from a curated library, g.nome is giving power to researchers — enabling them to import custom code, handle big datasets reliably, and optimize team collaboration from anywhere. With g.nome, long-time barriers linked to workflow language, process flow visibility, and quality control are removed. All that’s left are streamlined, scalable, and interoperable genomic workflows — leaving research teams to do what they do best: focus on the science. -
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OmicsBox
BioBam Bioinformatics S.L.
OmicsBox is a leading bioinformatics solution that offers end-to-end data analysis of genomes, transcriptomes, metagenomes, and genetic variation studies. The application is used by top private and public research institutions worldwide and allows researchers to easily process large and complex data sets, and streamline their analysis process. It is designed to be user-friendly, efficient, and with a powerful set of tools to extract biological insights from omics data. The software is structured in different modules, each with a specific set of tools and functions designed to perform different types of analysis, such as de-novo genome assemblies, genetic variation analysis, differential expression analysis, and taxonomic classifications of microbiome data, including the functional interpretation and rich visualizations of results. The functional analysis module includes the popular Blast2GO annotation methodology and makes OmicsBox particularly suited for non-model organism researchStarting Price: €100/month/seat -
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Genoox
Genoox
Through our diverse and growing community, Genoox accumulates the most relevant database and delivers actionable, real-world genomic insights that impact lives, improve clinical outcomes, and shape the business of healthcare. Our solutions are changing the face of genomics. Genoox uses the power of its community and combines public data with community data to streamline the path from DNA sample to clinical report, impacting patient care by making genomic data accessible and actionable at the point of care. Genoox enhances research and life sciences companies by providing an insight platform derived from real-world data and evidence and powered by our community with robust genomic analytics, helping researchers simplify complex genomic data and make impactful discoveries using the most advanced genetic tools and applications. Genoox helps biosystems companies such as DNA sequencing companies to bundle its state-of-the-art genomic engine with dedicated assays. -
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Emedgene
Illumina
Emedgene streamlines your tertiary analysis workflows for rare disease genomics and other germline research applications. Emedgene is designed to accelerate the time and certainty in user-defined variant interpretation, prioritization, curation, and research report generation. Enable greater efficiency from your tertiary analysis workflows with explainable AI (XAI) and automation supporting genomes, exomes, virtual panels, and targeted panels. Unify your laboratory and NGS instrumentation with your IT systems to simplify and secure your complete workflow. Confidently keep pace with evolving science, technology, and demand with up-to-date knowledge graph options, curation capabilities, and a team of experts to support your journey. Increase throughput without increasing headcount using explainable AI (XAI) and automated workflows. Implement a high throughput WGS, WES, virtual panel, or targeted panel workflow that is integrated into your lab's digital ecosystem. -
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Profluent
Profluent
Profluent's platform revolutionizes protein design by integrating advanced AI with in-house wet-lab capabilities, enabling the creation of proteins either inspired by nature or reimagined from scratch. This holistic approach allows for precise, adaptable, and scalable solutions to complex biological challenges, delivering results that redefine what's possible with proteins. Profluent's foundation models push the frontier of protein design beyond the limitations of random discovery, facilitating the optimization of multiple attributes simultaneously, accessing greater sequence diversity, and enabling novel functionalities. By extrapolating into new protein spaces, Profluent offers unique possibilities beyond natural or patented proteins, making it cheaper, easier, and feasible for partners to achieve commercial success. Profluent's capabilities are built on a commitment to scientific rigor, leveraging diverse datasets and advanced AI to tackle challenges. -
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ESMFold2
Biohub
ESMFold2 is the successor to ESMFold, setting a new state of the art for single-sequence structure prediction and enabling the generation of new functional proteins through searching the ESMC model’s latent space. The model predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequence, with optional multiple sequence alignment input for enhanced accuracy on challenging targets. It is designed for structure prediction using sequence and structure modalities, with ESM representations powering a series of looped folding layers and a diffusion model projecting pairwise representations to atomic-resolution predictions. ESMFold2 predicts protein structures directly from amino acid sequences and outputs comprehensive structural information, including all-atom coordinates for backbone and side chains, confidence metrics, and optional distogram predictions for detailed structural analysis.Starting Price: Free -
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GeoMx Digital Spatial Profiler (DSP)
nanoString
Quickly resolve tissue heterogeneity and the complexity of microenvironments with the GeoMx Digital Spatial Profiler (DSP), the most flexible and robust spatial multi-omic platform for analysis of FFPE and fresh frozen tissue sections. GeoMx is the only spatial biology platform that non-destructively profiles the expression of RNA and protein from distinct tissue compartments and cell populations with an automated and scalable workflow that integrates with standard histology staining. Spatially profile the whole transcriptome and 570+ protein targets separately or simultaneously from your choice of sample inputs: whole tissue sections, tissue microarrays (TMAs), or organoids. Make GeoMx DSP your spatial biology platform of choice for biomarker discovery and hypothesis testing. Decide where to draw the line and let the tissue be your guide with biology-driven profiling that empowers you to choose the tissue microenvironments and cell types that matter most to you. -
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SciSpace BioMed Agent
SciSpace
SciSpace BioMed is a domain-native AI “co-scientist” for biomedical research that combines a vast literature database with 150+ integrated bio-tools and 100+ academic databases and software suites to streamline complex research workflows, from genomics and single-cell analysis to drug discovery and clinical genomics. It enables researchers to ask natural-language questions, ingest datasets, interpret variants or multi-omics data, design cloning or wet-lab workflows, reason about clinical or disease biology, and generate publication-ready outputs (e.g., figures, tables, and presentations) with full transparency and citations. Users can interact with scientific papers via “chat with PDF,” highlight confusing text, math, or tables, and get clear explanations, ideal for understanding difficult methods or concepts. For literature review or exploratory research, its AI-driven semantic search accesses millions of papers and returns citation-backed summaries.Starting Price: $12 per month -
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Cellenics
Biomage
Turn your single-cell RNA sequencing data into meaningful insight with Cellenics software. Biomage hosts a community instance of Cellenics, an open source analytics tool for single-cell RNA sequencing data that has been developed at Harvard Medical School. It enables biologists to explore single-cell datasets without writing code and helps scientists and bioinformaticians to work together more effectively. It takes you from count matrices to publication-ready figures in just a few hours and can be integrated seamlessly with your workflow. It’s fast, interactive, and user-friendly. And it’s cloud-based, secure, and scaleable. The Biomage-hosted community instance of Cellenics is free for academic researchers with small/medium-sized datasets (up to 500,000 cells). It’s used by 3000+ academic researchers studying cancer, cardiovascular health, and developmental biology.Starting Price: Free -
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Correlation Engine
Illumina
Correlation Engine is an interactive omics knowledgebase that puts private omics data in a biological context with highly curated public data. One of the largest biological databases in the world, Correlation Engine provides life science researchers with unprecedented access to vast numbers of high-quality whole-genome analyses and insightful scientific tools. The knowledgebase enables novel discoveries by interrogating billions of data points derived from standardized analyses of whole genome studies. A suite of applications to determine biological context, a continually growing library of curated data sets, and support for multiple species and multi-omic datasets. Utilize a simple graphical user interface to leverage guided workflows, push-button applications, and APIs. Accelerate your journey from omic data to decision and get access to over 25,000 multi-omics studies (from over 250,000 signatures) that have been reanalyzed. -
40
FutureHouse
FutureHouse
FutureHouse is a nonprofit AI research lab focused on automating scientific discovery in biology and other complex sciences. FutureHouse features superintelligent AI agents designed to assist scientists in accelerating research processes. It is optimized for retrieving and summarizing information from scientific literature, achieving state-of-the-art performance on benchmarks like RAG-QA Arena's science benchmark. It employs an agentic approach, allowing for iterative query expansion, LLM re-ranking, contextual summarization, and document citation traversal to enhance retrieval accuracy. FutureHouse also offers a framework for training language agents on challenging scientific tasks, enabling agents to perform tasks such as protein engineering, literature summarization, and molecular cloning. Their LAB-Bench benchmark evaluates language models on biology research tasks, including information extraction, database retrieval, etc. -
41
Genospace
Genospace
At Genospace, we understand that genomics is driving the development of precision medicine, yet scaling its delivery is an unsolved challenge. We’re here to help. Our platform is designed to make biomedical data meaningful and accessible to everyone, especially those on the front lines of care delivery. Arm your clinicians and researchers with the information they need to make informed decisions and join us in our mission of leveraging high-dimensional molecular data to improve individual patient outcomes and accelerate drug development and research. Large-scale population data is necessary for drug development and research. Conduct cohort-driven analyses to inform your research activities with the Genospace platform. We specialize in clinical trial research. Use the Genospace platform to match fragmented patient data to complex trial criteria and expedite patient accruals. Integrate genomic medicine into mainstream clinical care with the Genospace platform. -
42
Loupe Browser
10x Genomics
Loupe Browser is a powerful visualization software that provides the intuitive functionality you need to explore and analyze your 10x Genomics Chromium and Visium data. You can also convert your Seurat objects into Loupe Browser files using the LoupeR package. The navigation and interactive functionality of the Loupe Browser interface uses a lung squamous cell carcinoma dataset. The workspace is centered around the view panel in which single points representing cell barcodes are shown in a variety of projections. Each point represents a single barcode, the vast majority of which correspond to a single cell. The default projection is the t-SNE plot created by the cell ranger pipeline, though other projections are available. You can drag the mouse over the cells to reposition the plot and use the mouse wheel or trackpad to zoom in and out. Cluster labels appear as you move your mouse over the plot, which is useful for data that has a high number of precomputed clusters. -
43
Kanteron
Kanteron Systems
Kanteron Platform ingested medical images, digital pathology slides, genomics sequences, and patient data from modalities, scanners, sequencers and databases, and provided a complete data toolkit to every team in hospital networks. Pharmacogenomics for adverse medication event prevention, and Precision Medicine application at the point of care: Incorporates sources of drug-gene interaction data that were previously only available in in accessible formats (e.g. tables in a PDF document), implementing the major Pharmacogenomic databases (like PharmGKB, CGI, DGIdb, OpenTargets...) Allows the user to refine their query to certain gene families, types of interactions, classes of drugs, etc. Flexible AI means you can choose the data set that best fits your use case, and apply it to your relevant medical images. -
44
Alissa Interpret
Agilent Technologies
Alissa Interpret is your universal genomic data interpretation software for clinical decision support. Increase your productivity, shorten the turnaround time, and maintain regulatory compliance with Alissa Interpret’s agnostic CGH and NGS tertiary analysis platform for variant interpretation and reporting. Achieve complete operational efficiency when pairing Alissa Interpret with Agilent’s fully optimized SureSelect NGS reagents, intuitive secondary NGS analysis Alissa Reporter, Magnis walkaway automation, and TapeStation QC for a streamlined NGS data analysis workflow. External and internal curated variant knowledgebases at your fingertips. Automated variant interpretation solution accelerates CGH and NGS tertiary analysis. One platform for SNVs, InDels, CNVs, LOH, and fusions. Integrate with your LIMS and eliminate genomic data analysis bottlenecks. Connect with peers, share knowledge, and improve diagnostic yield. -
45
Congenica
Congenica
We drive precision medicine and help reduce the burden on healthcare systems by delivering automated analysis, diagnosis, and treatment solutions to healthcare providers and patients worldwide. Congenica was founded on pioneering work at the Wellcome Sanger Institute and the UK NHS. Our products combine state-of-the-art technology, market-leading automation, and AI to enable our uniquely differentiated platform to be employed in all areas of human disease where genomic information is key to unlocking actionable insights. We are a digital health company providing software and solutions for the analysis and interpretation of genomic data at scale. Full automation with powerful APIs and ML to reduce the burden on specialist staff, maximize case throughput, accelerate decision-making, and streamline reporting. Certified, accurate, and secure analysis platform to support clinical decisions with the highest degree of confidence in the clinical outcome. -
46
Genedata Biologics
Genedata
Genedata Biologics® streamlines discovery of biotherapeutics including bispecifics, ADCs, TCRs, CAR-Ts, and AAVs. The most widely adopted platform across the industry, it integrates all discovery workflows so you can focus on true innovation. Accelerate research with a first-in-class platform uniquely designed from the start to digitalize biotherapeutic discovery. The platform facilitates complex R&D processes by designing, tracking, testing, and assessing novel biotherapeutics drugs. It works with any format, from antibodies, bi- or multi-specifics, ADCs, novel scaffolds, and therapeutic proteins, to engineered therapeutic cell lines such as TCRs and CAR-T cells. Acting as a central end-to-end data backbone, Genedata Biologics integrates all R&D processes, from library design and immunizations, selections and panning, molecular biology, screening, protein engineering, expression, purification, and protein analytics, to candidate developability and manufacturability assessments. -
47
NVIDIA BioNeMo
NVIDIA
BioNeMo is an AI-powered drug discovery cloud service and framework built on NVIDIA NeMo Megatron for training and deploying large biomolecular transformer AI models at a supercomputing scale. The service includes pre-trained large language models (LLMs) and native support for common file formats for proteins, DNA, RNA, and chemistry, providing data loaders for SMILES for molecular structures and FASTA for amino acid and nucleotide sequences. The BioNeMo framework will also be available for download for running on your own infrastructure. ESM-1, based on Meta AI’s state-of-the-art ESM-1b, and ProtT5 are transformer-based protein language models that can be used to generate learned embeddings for tasks like protein structure and property prediction. OpenFold, a deep learning model for 3D structure prediction of novel protein sequences, will be available in BioNeMo service. -
48
Galaxy
Galaxy
Galaxy is an open source, web-based platform for data-intensive biomedical research. If you are new to Galaxy start here or consult our help resources. You can install your own Galaxy by following the tutorial and choosing from thousands of tools from the tool shed. This instance of Galaxy is utilizing infrastructure generously provided by the Texas Advanced Computing Center. Additional resources are provided primarily on the Jetstream2 cloud via ACCESS, and with support from the National Science Foundation. Quantify, visualize, and summarize mismatches in deep sequencing data. Build maximum-likelihood phylogenetic trees. Phylogenomic/evolutionary tree construction from multiple sequences. Merge matching reads into clusters with TN-93. Remove sequences from a reference that are within a given distance of a cluster. Perform maximum-likelihood estimation of gene essentiality scores.Starting Price: Free -
49
DNAnexus Titan
DNAnexus
DNAnexus Titan™ powers the future of genomics research and clinical pipelines with trusted, high-performance data analysis solutions. Legacy informatics tools were not designed to manage today's higher volumes of sequencing data. With home-grown, do-it-yourself systems, research centers and clinical diagnostic testing companies are finding it difficult and time-consuming to create, refine, validate, and execute pipelines at scale. DNAnexus Titan™ removes bottlenecks in development and production with a unified platform that brings all your data and pipelines together in one place and delivers unparalleled efficiencies. Leave the heavy lifting of managing industry and region-specific security and compliance requirements to us, while meeting the growing global demand for sequencing data. -
50
VSClinical
Golden Helix
VSClinical allows for the clinical interpretation of variants based on ACMG & AMP guidelines. The VSClinical guided workflow enables following the American College of Medical Genetics (ACMG) guidelines used to identify and classify causal variants for inherited disease risk, cancer predisposition, and the diagnosis of rare diseases. The ACMG/AMP joint guidelines for variant interpretation provide a set of criteria to score variants and place them into one of five classification tiers. Following the guidelines requires deep diving into the annotations, genomic context, and existing clinical assertions about every variant. VSClinical provides a tailored workflow to score each relevant criterion while also providing all the bioinformatic, literature and evidence from clinical knowledgebases to assist in the scoring and interpretation process. VSClinical is designed to allow variant scientists to efficiently process variants.
