Claude Mythos 5.1
Claude Mythos 5.1 is Anthropic’s newest Mythos-class model, designed for advanced cybersecurity, biology, scientific research, coding, and long-running knowledge work. It is the same underlying model as Claude Fable 5.1 but uses different safeguards: Fable 5.1 is generally available, while Mythos 5.1 is restricted to trusted access programs with safeguards specifically designed for cybersecurity and life sciences research. The model sets a new performance frontier for agentic coding and demonstrates the strongest cyber capabilities of any Anthropic model released to date. In scientific research, Mythos 5.1 can work with specialized tools and complex workflows across molecular design, computational biology, and other technical domains. In Anthropic’s experiments, it designed high-affinity protein binders across multiple targets and achieved its strongest measured hit rate to date. It also optimized seven open-source protein and genomics deep learning models.
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ESMC
ESMC is the latest in the ESM family of protein language models, establishing a new frontier in representation learning for protein biology. Trained on billions of evolutionary sequences, it learns representations that reflect a mechanistic reduction of protein structure and function. The model is built on a transformer architecture, supports sequences as its core modality, and is trained on up to 6 billion proteins. ESMC is designed for protein science research, including structure prediction, function annotation, protein design, and understanding evolutionary relationships between proteins. It can generate novel proteins from partial sequence, structure, or functional constraints, helping researchers explore new possibilities in protein design and biological discovery. The Biohub Platform provides access to ESMC through the API and the ESM Python package, with quickstart resources for installing the package, creating an API key, connecting to the platform.
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Claude Mythos 5
Claude Mythos 5 is Anthropic’s most advanced restricted-access AI model, designed for trusted cyberdefenders, infrastructure providers, and select research organizations. It uses the same underlying model as Claude Fable 5 but provides lifted safeguards in approved areas for specialized high-trust use cases. The model delivers exceptional capabilities in cybersecurity, software engineering, scientific research, long-context reasoning, vision, and autonomous task execution. Anthropic initially deployed Claude Mythos 5 through Project Glasswing in collaboration with the U.S. government to help protect critical software and infrastructure. The model also shows strong potential in life sciences, including protein design, molecular biology hypothesis generation, and genomics research. Claude Mythos 5 is built for organizations that need frontier AI capabilities under controlled, trusted-access conditions.
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HyperProtein
HyperProtein is Hypercube, Inc.'s new product focusing on the computational science associated with protein sequences. The product includes the analysis of one-dimensional protein sequences as well as the analysis of consequent three-dimensional protein structures. In particular, the relationship between sequence and structure is a fundamental facet of the product. Unlike individual software programs that provide capability for some aspect of protein sequence or structure, such as sequence alignment, HyperProtein puts together a multitude of Bioinformatics and Molecular Modeling tools related to the science that initiates with a protein sequence.
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