Showing 90 open source projects for "command line developer tools"

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  • 1
    SAM (Sequence Alignment/Map) is a flexible generic format for storing nucleotide sequence alignment. SAMtools provide efficient utilities on manipulating alignments in the SAM format. The main samtools source code repository moved to GitHub in March 2012. For ongoing development since then, see http://github.com/samtools/samtools
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    4.7 out of 5 stars 21 Reviews
    Downloads: 1,976 This Week
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  • 2
    Bowtie 2

    Bowtie 2

    A fast and sensitive gapped read aligner

    Bowtie 2 is a fast, memory-efficient genomic read aligner used to map sequencing reads against long reference sequences such as mammalian genomes. It is especially effective for reads ranging from around 50 bases to hundreds or thousands of characters, and it supports modern sequencing workflows that require gapped, local, and paired-end alignment. The tool builds compact FM-index-based reference indexes, keeping memory usage low even for large genomes like the human genome. Bowtie 2 outputs...
    Downloads: 1 This Week
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  • 3
    The Sashimi project hosts the Trans-Proteomic Pipeline (TPP), a mature suite of tools for mass-spec (MS, MS/MS) based proteomics: statistical validation, quantitation, visualization, and converters from raw MS data to the open mzML/mzXML formats.
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    Downloads: 209 This Week
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  • 4
    MAF

    MAF

    Bash Framework to combine many preprocessing and alignment tools

    DNA and RNA nucleotide sequences are an ubiquitous element of all biological cells and are serving on one hand as a comprehensive library of capabilities for the cells and on the other as an impressive regulatory system to control cellular function. The presented multi-alignment framework (MAF) should give researchers a simple sequence alignment platform as a functional template, flexible enough to adjust all steps but also comprehensive enough to join many different tools and custom...
    Downloads: 0 This Week
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  • 5
    AMBIT:Chemical Structure DB&Web Service

    AMBIT:Chemical Structure DB&Web Service

    Chemical structures database & machine learning with web services API

    ...Flexible structure, similarity and study queries storage, descriptor calculation and predictive models building via REST web services.User interface for creating read across assessment and generating reports, aligned with regulatory and industrial requirements. Command line applications also available. Integration with third party tools and databases.
    5.0 out of 5 stars 1 Review
    Downloads: 1 This Week
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  • 6

    GromacsProSuite

    Graphical User Interface for Gromacs

    This tool is an integrated graphical interface that simplifies molecular dynamics simulations using Gromacs. It provides a structured, tab-based environment to set up, execute, and analyze simulations data without complex command-line operations. The software automates tasks such as topology generation, solvation, ion addition, minimization, equilibration, and production runs while executing GROMACS commands in the background. Built-in monitoring tracks CPU, RAM, and disk usage to ensure stable performance during parallel processing. Beyond simulation execution, it includes advanced trajectory processing and analysis tools such as RMSD, RMSF, SASA, clustering, PCA, hydrogen-bond analysis, Ramachandran plots, and FEL mapping. ...
    5.0 out of 5 stars 8 Reviews
    Downloads: 0 This Week
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  • 7
    miRDeep*

    miRDeep*

    MiRDeep*

    Please cite: An, J., Lai, J., Lehman, M.L. and Nelson, C.C. (2013) miRDeep*: an integrated application tool for miRNA identification from RNA sequencing data. Nucleic Acids Res, 41, 727-737. We will create index for you if you tell us your interested species (j.an@qut.edu.au). download command line version "MDS_command_line_Vxx.zip" clicking "Browse All Files" please find miRPlant in sourceforge for plant miRNA prediction.
    Downloads: 4 This Week
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  • 8

    uac19

    Analyze COVID-19 csv files

    A flexible command line tool to analyze COVID-19 csv files https://github.com/nytimes/covid-19-data https://ourworldindata.org/coronavirus-source-data The rpm build is rh7 the tgz installs on Windows cygwin.
    Downloads: 0 This Week
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  • 9
    MiModD

    MiModD

    Mutation Identification in Model Organism Genomes using Desktop PCs

    MiModD is a software package for genomic variant identification from next-generation sequencing (NGS) data with optimized usage of system resources and a user-friendly interface. For most model organism genomes it lets the user carry out a complete analysis from unaligned genomic NGS read data to an annotated list of variants on a regular Desktop PC within a few hours. Its user-interface is beginner-friendly and designed to encourage geneticists to analyze NGS data themselves without the...
    4.5 out of 5 stars 2 Reviews
    Downloads: 1 This Week
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  • 10

    PINCIS

    PINCIS.pl is a Perl bioinf. script to analyze PICS data

    PINCIS.pl (PIcs N-/C-terminal Inferred Substrates perl script) is a small, command line tool to designate and analyze PICS (Schilling et al., Nat. Protocols, 2011) data to gain the prime and non-prime site specificity of proteases. Thus, the script filters given peptide lists for library peptides (generated by the digestion protease in the proteomics workflow rather then the protease of interest) and prints out lists of inferred N- and C-terminal cleavage window extensions which can be...
    Downloads: 0 This Week
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  • 11
    GenSeed-HMM

    GenSeed-HMM

    Progressive assembly tool using DNA, protein or profile HMMs as seeds.

    GenSeed-HMM is a program for seed-driven progressive DNA assembly. It differs from the previously published GenSeed in many aspects, but more pointedly by being able to use an HMM profile as seed. Basically, GenSeed-HMM performs three operations, repeatedly: - recruit reads by matching them to a seed - assemble the recruited reads (including previously assembled contigs) - generate new seeds (for the next round of progressive assembly) from the extremities of all generated...
    Downloads: 1 This Week
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  • 12
    LibSEDML: Sharing Simulation Experiments
    This project hosts a library and tools for sharing simulation experiments encoded using SED-ML.
    Downloads: 0 This Week
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  • 13
    TaxOnTree

    TaxOnTree

    A program for associating taxonomic information in a phylogenetic tree

    ...Also, a newick file produced with user software and specific settings can be used to proceed with the taxonomic labeling. TaxOnTree turns its user into an expert on taxonomy. TaxOnTree also corrects for the absence of some taxa in NCBI taxonomy. Command line program is easy to set up and can be coupled to several bioinformatics tools, producing a colored tree in PDF format. TaxOnTree is available as a web tool in http://biodados.icb.ufmg.br/taxontree for low demanding jobs.
    Downloads: 0 This Week
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  • 14
    gsasnp2

    gsasnp2

    PubMed ID: 29562348 / DOI: 10.1093/nar/gky175

    * GSA-SNP2 is a successor of GSA-SNP (Nam et al. 2010, NAR web server issue). GSA-SNP2 accepts human GWAS summary data (rs numbers, p-values) or gene-wise p-values and outputs pathway genesets ‘enriched’ with genes associated with the given phenotype. It also provides both local and global protein interaction networks in the associated pathways. * Article: SYoon, HCTNguyen, YJYoo, JKim, BBaik, SKim, JKim, SKim, DNam, "Efficient pathway enrichment and network analysis of GWAS summary data...
    Downloads: 206 This Week
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  • 15

    PTESFinder

    Post-Transcriptional Exon Shuffling (PTES) Identification Pipeline

    PTESFinder is a computational pipeline for identifying Post-transcriptional Exon Shuffling events from high-throughput RNAseq data. PTESFinder leverages the power of established RNASeq tools and systematically excludes all known classes of false positive structures by applying stringent filters designed to specifically target these false positives. PTESFinder compares alignment qualities of reads mapping to putative PTES structures with qualities of the same reads when mapped to genomic...
    Downloads: 0 This Week
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  • 16
    The Elvira project is a suite of tools to perform high-throughput genomic assemblies of repetitive, structured samples such as viruses or targeted regions of larger genomes.
    Downloads: 0 This Week
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  • 17
    CompleXChange

    CompleXChange

    differential analysis of combinatorial protein complexes

    The increasing wealth of transcriptomic data and current computational tools enable to infer how protein interactomes and complexomes may be assembled in specific samples. With CompleXChange this information can be exploited to conduct differential analyses of the dynamic protein complexome in a quantitative manner. The corresponding publication can be found on https://doi.org/10.1186/s12859-019-2852-z.
    Downloads: 0 This Week
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  • 18
    ChIP-Seq
    The ChIP-Seq software provides methods for the analysis of ChIP-seq data and other types of mass genome annotation data. The most common analysis tasks include positional correlation analysis, peak detection, and genome partitioning into signal-rich and signal-depleted regions.
    Downloads: 1 This Week
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  • 19
    CSBB-v3.0

    CSBB-v3.0

    CSBB - Computational Suite for Bioinformaticians and Biologists

    CSBB is a command line-based bioinformatics suite to analyze biological data acquired through varied avenues of biological experiments. CSBB is implemented in Perl, while it also leverages the use of R, java, python and ruby in background for specific modules. Major focus of CSBB is to allow users from biology and bioinformatics community, to get benefited by performing down-stream analysis tasks while eliminating the need to write programming code. CSBB is currently available on Linux,...
    Downloads: 0 This Week
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  • 20

    BisSNP

    Bisulfite-seq/NOMe-seq SNPs & cytosine methylation caller

    Now in Github: https://github.com/dnaase/Bis-tools/tree/master/Bis-SNP BisSNP is a package based on the Genome Analysis Toolkit (GATK) map-reduce framework for genotyping in bisulfite treated massively parallel sequencing (Bisulfite-seq, NOMe-seq and RRBS) on Illumina platform. It uses bayesian inference with either manually specified or automatically estimated methylation probabilities of different cytosine context(not only CpG, CHH, CHG in Bisulfite-seq, but also GCH et.al. in other...
    Downloads: 5 This Week
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  • 21
    HitKeeper is a database application for use in BioInformatics. It deals with "hits" (predicted features) on biological sequences (protein, DNA), handles incremental updates effectively, supports taxonomy, and provides original query tools.
    Downloads: 0 This Week
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  • 22
    RoadRunner represents a state-of-the-art simulation library for SBML models. It is fast, portable and accurate. This projects hosts the library and tools using the library.
    Downloads: 0 This Week
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  • 23
    Krona

    Krona

    Hierarchical data browser

    Krona allows hierarchical data to be explored with zoomable HTML5 pie charts. Krona charts can be created using an Excel template or Krona Tools, which includes support for several bioinformatics tools and raw data formats.
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    Downloads: 0 This Week
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  • 24
    Suite of tools for DNA sequence analysis - searching (EST, mRNA, sequencer reads); aligning (ESTs, mRNA, whole genome); and analysis (repeats, kmers).
    5.0 out of 5 stars 1 Review
    Downloads: 7 This Week
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  • 25

    GFinisher

    genome assembler finisher, gap, gap close, sort contig

    GFinisher is an application tools for refinement and finalization of prokaryotic genomes assemblies using the bias of GC Skew to identify assembly errors and organizes the contigs/scaffolds with genomes references. contact dievalg at gmail.com
    Downloads: 3 This Week
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