Best Enterprise Therapy Software of 2026

Opus

Opus is a comprehensive EHR, CRM, and RCM platform designed to streamline operations for behavioral health treatment centers, including addiction, mental health, and SUD (substance use disorder) clinics. The platform provides integrated tools for patient management, billing, scheduling, and telehealth services. Opus enhances efficiency with features like intelligent lead routing, insurance verification, automated tasks, and customizable forms. It also includes advanced reporting, AI-driven progress note generation, and seamless lab integrations. With a focus on flexibility and scalability, Opus is ideal for small to large multi-center organizations in the behavioral health space.

93 Ratings

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RXNT

RXNT is an ambulatory healthcare technology pioneer that empowers medical practices and healthcare organizations to succeed and scale through innovative, data-backed, AI-powered software. Our fully-integrated, ONC-certified suite of medical software—like Clinical EHRs, Practice Management, Medical Billing and RCM, E-Prescribing, Practice Scheduling, Patient Portal, and more—optimizes clinical outcomes and RCM for your practice. Used by tens of thousands of medical professionals—from large physician practices to medical billing companies—to drive growth, streamline business operations, and improve patient care across all 50 U.S. states. Our unified “Full Suite” system employs a secure, central database so your data passes through every product in real-time from anywhere, and more than 125 million prescriptions have been transmitted and over $7 billion in claims have been processed using RXNT.

549 Ratings

Starting Price: $118/month

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AdvancedMD

AdvancedMD is a comprehensive cloud-based medical office management software designed to streamline operations for private healthcare practices. It combines practice management, electronic health records (EHR), and patient engagement tools into a single unified platform. The software uses AI-driven automation to simplify clinical, financial, and administrative workflows, reducing manual tasks and improving efficiency. Features like ambient listening for clinical documentation, automated patient intake, and computer-assisted coding help accelerate everyday processes. AdvancedMD enables healthcare providers to focus more on patient care by minimizing administrative burden. The platform also supports revenue cycle management, improving billing accuracy and cash flow. With secure cloud hosting on AWS, users can access the system from any device, anywhere. Overall, it delivers an integrated solution that enhances productivity, patient outcomes, and practice performance.

2 Ratings

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Acuity Scheduling

Squarespace

Make online appointment scheduling and management a breeze with Acuity Scheduling. Acuity Scheduling is an easy to use online appointment scheduling software that helps professionals and businesses fill their schedule--minus all the hassle. With Acuity, clients see your real-time availability, book appointments fast, and pay in advance. All without you needing to organize and reorganize things.

6,294 Ratings

Starting Price: $16.00/month

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Mercury One Plus

CrisSoft

Mercury One Plus is a Medical Practice Management solution that puts the fundamentals of Revenue Cycle Management at your fingertips; it acts as a stepping stone from standard billing to intermediate billing. Mercury One Plus is offered exclusively on the cloud, with the highest level of security- you can access your data anywhere 24/7. A complete product with big functionality, Mercury One Plus includes: patient demographics input, 100 plus reports to choose from, charge entry, full history of patient activity, ERA posting, credit card acceptance, and much more. Mercury Products are HIPAA compliant with a guaranteed connection to any clearinghouse or insurance company. Mercury One Plus's automated job system will facilitate a daily system tune-up: housecleaning; folder maintenance; daily backups; 837 exports; 835 imports;HL7. All subscriptions come with the expert help of CrisSoft Support. Willing to partner/intergrate with all EMR's through REST.

12 Ratings

Starting Price: $249.00

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Sunwave

Sunwave Health

Sunwave Health (Sunwave) drives healthy results for mental health and Substance Use Disorder treatment providers through a fully integrated solution that supports the entire treatment journey. Sunwave supports traditional capabilities provided by CRM, EMR, RCM, HR, and billing solutions. But we go further to ensure results. As the only 4th generation, fully integrated treatment journey platform, we drive outcomes using complete analytics, on-demand intelligence, and intuitive reporting. There is a reason we are the highest rated in customer satisfaction. See for yourself. With Sunwave, mental health and Substance Use Disorder treatment providers can attract more qualified patients, accelerate the admissions process, improve care coordination, drive length of stay, improve revenue, and optimize clinical resources.

11 Ratings

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AZZLY

AZZLY Rize is the premier clinical and business platform for addiction treatment and mental health organizations. As an all-in-one substance use disorder and mental health specific EHR, Patient Engagement and RCM platform, we serve small, medium, and large clinics. Key features for OUTPATIENT Programs include: scheduling, appointment reminder, Zoom telehealth, treatment plans, progress notes, assessments and surveys. For RESIDENTIAL programs: census, medication management, bed board, withdrawal management, DrFirst e-prescribing, EPCS, PDMP, labs. For all levels of care: alerts, patient engagement portal, electronic billing and claims submission built in. AZZLY Rize empowers your staff through its 5 star training and support services, its simplicity and automation. As a true all-in-one EHR/PM/RCM platform, improved compliance, workflow and accurate billing are achieved real-time. We proudly serve programs in over 33 states and are hosted in Microsoft Azure's private cloud network.

3 Ratings

Starting Price: $50/user/month

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Foothold

Foothold Technology

Our human services software offers full functionality for case management, client tracking, electronic health record (EHR), and homeless information management (HMIS) all under one roof. We work with agencies across the spectrum of human services: including developmental disabilities, mental health, substance use disorder, homelessness, supportive housing, HCBS, and much more. Foothold is HIPAA-compliant mental health software, federally certified as an EHR, and offers full interoperability as you navigate the new landscape of care coordination and value-based care. Transform the way you provide care with nimble software and a partnership guided by experience.

2 Ratings

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MedEZ

MedEZ exists to be your comprehensive, all-in-one paperless solution. In business since 1995, MedEZ has streamlined the entire practice management/EHR and clinical note process. MedEZ specializes in automating the daily operations of behavioral health and substance use facilities. These include: administration, patient management, clinical, billing and business intelligence. MedEZ provides customized EHR products that optimize the financial, operational, and clinical performance aspects of medical practices. MedEZ allows the creation of customizable programs and treatment plans offered at behavioral health centers. MedEZ also handles required documentation and reporting efficiently. It ensures HIPAA-compliance with checkpoints that have user-defined security levels based on permission.

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BPAUS

A digital platform designed for healthcare providers and practitioners of autism and developmental disabilities. BPAUS includes a comprehensive suite of digital tools that enable the creation, tracking, and documentation of treatment processes in kindergartens, schools, and private institutions. A parent portal enables collaboration between parents and professionals, by making a treatment diary and a graphical presentation of the progress of the treatment. The system operates in a simple and user-friendly interface removing the need to change work methods and processes.

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Calmerry

Calmerry provides comprehensive online therapy and employee mental health benefits that transform workplace wellness. We partner with businesses to boost team performance, reduce absenteeism, and enhance productivity through customized mental health solutions. Our platform instantly matches employees with licensed therapists in their state, delivering quality mental healthcare through text-based support, live video sessions, and personalized therapy plans. We offer flexible payment packages tailored to your business needs. Our employee mental health benefits feature streamlined onboarding for both administrators and team members, achieving utilization rates up to three times higher than traditional EAPs. The complimentary self-help toolbox extends online therapy support beyond standard benefits. Ready to enhance your team's well-being? Contact us to learn how our online therapy platform can support your organization.

10 Ratings

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Clinicea

We're the best all-in-one, cloud-based, clinic management platform for growing, ambitious clinics. Clinicea is loved for its unique technology that can replicate paper to generate a super-specialised EMR for you. Deploy virtual assistants to get questionnaires filled, and consents signed. Already in use by 40 specialities across 5 continents. Engage 24x7. Deploy white labelled tools for Online Bookings, Patient Portals, Auto-Invoicing. There’s lots more. No apps, no downloads, just a click. Comprehensive, easy and does it all. Take a demo and see live what the next-generation technology can do for you.

3 Ratings

Starting Price: $59 per user per month

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Theralytics

Theralytics was created to provide ABA practices with a comprehensive, user-friendly practice management solution. Developed by Board Certified Behavior Analysts and healthcare technology experts, Theralytics simplifies the complexities of managing an ABA practice while ensuring top-level security and efficiency. Designed specifically for ABA providers, Theralytics offers an all-in-one platform to optimize operations with features like data collection, scheduling, billing, and real-time analytics. By streamlining workflows and enabling data-driven decision-making, ABA practices can focus more on delivering quality care. Plus, with its affordable pricing, Theralytics caters to practices of all sizes, offering a cost-effective solution that meets the unique needs of ABA management.

3 Ratings

Starting Price: $150 per month

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ReadySetConnect

ReadySetConnect is a practice management software. It is designed to be a complete support tool for clinicians and educators so they can perform their work efficiently and dependably. All patient charts are in one place and can be accessed easily. Users can track and review progress on goals, compare data, collaborate and make timely and effective decisions that help them succeed. This easy-to-set-up software solution is HIPAA-compliant. Unite Your Team: Access ReadySetConnect from any device to meet unique challenges faced by your team and enhance productivity. Effectively Supervise Clinicians And Assistants: In-built workflow enables easy access to review caseloads, schedules, records, and interactions. Collaborate And Gain Confidence With Your Shareholders: Dynamic access rights for your payors and clients to share data in real-time. Make Better-Informed Decisions: Data helps review and analyze each team's performance and inform future planning.

1 Rating

Starting Price: Free

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Medesk

Ideal for medical practitioners and private clinics, it is a cloud-based platform that streamlines your practice workflow, helping you attract and retain more patients at a lower cost. Medesk offers video consultations, in-built EHR, a schedule integrated with Google Calendar and iCal, online booking and appointment reminders, powerful analytics, and payment and deposit options. Medesk has developed ready-made solutions for GPs, mental health, allied health, and hair loss practitioners. Medesk allows you to automate the patient engagement process with the following tools: – Transparent online booking with convenient time slots available –Adding patient contact details straight to their EHR for immediate use – Automated confirmation emails and textsright after booking – Schedule reminders to cut down on cancellations and DNAs

1 Rating

Starting Price: $15.00/month

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TherapyMate

TherapyMate is an easy-to-use web-based practice management platform purpose-built for mental and behavioral health professionals that include therapists, counselors, psychologist, psychiatrists, and social workers. Smart, scalable, and secure, TherapyMate offers a host of features and capabilities that include business document management, scheduling, calendaring, therapy notes, appointment reminders, credit card processing, insurance billing, income and expense tracking, and more.

1 Rating

Starting Price: $29.00/month

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PracticeHarmony

Mahler Health

Practice Harmony is the premier practice management tool for running your healthcare practice. Our cloud-based practice management software solution streamlines your practice's operations and optimizes your workflow. Robust scheduling, advanced EHR, customized forms, patient dashboard, optimized voice-to-text, full RCM, TeleMedicine, TelePsychiatry, eRx, HIPAA Compliant CRM, and so much more. Streamlined operations require the perfect orchestration of efficient patient scheduling, proper documentation, and successful billing. Run your entire practice from scheduling to billing with just one log-in. Schedule a demo today to learn how you can bring Harmony to your Practice.

1 Rating

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Meditab IMS

Meditab Software

Our all-in-one multi-specialty EHR, Practice Management, and Billing software solution allow doctors to deliver the highest quality of care possible to their patients. Streamline your practice's workflows, optimize financial performance, and coordinate quality care faster with IMS. Your practice can’t fully thrive with an inadequate EHR. That’s why Meditab designed its core EHR software, IMS, to do it all. One of the country’s leading EHR software companies, Meditab empowers practices to succeed with innovative technology and one-of-a-kind flexibility. So much more than a typical EMR software, IMS integrates every aspect of your practice into one comprehensive ecosystem. Imagine having an EHR with integrated practice management, medical billing, ICD-10 codes, patient engagement, telemedicine features, and more, you can save time and money while improving your practice efficiency. When your EHR does it all, you can elevate your quality of care and ensure a thriving business.

1 Rating

Starting Price: $199.00/month/user

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Spruce Health

Modern healthcare communication. Spruce is the simplest and most powerful way for patients, healthcare providers, and other partners in health to connect and communicate. Spruce integrates your existing communication methods with new tools, all in one easy-to-use inbox. One supercharged team inbox for all communication. With Spruce, you can communicate with both your teammates and your patients in one HIPAA-compliant inbox. Managing patient requests, listening to voicemails, and responding quickly is easy when everything is all in one place. Reach patients with the right message at the right time. Great care starts with a proactive approach. With Spruce, you can effectively reach patients before a problem turns into an emergency – helping you build stronger relationships and deliver more efficient care. With virtual care and complex workflow automation, you and your team can cover more ground and avoid unnecessary repetition.

1 Rating

Starting Price: $24 per user per month

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FelicityCare

It's an Online Mental Health Counseling Platform. We have 80+ verified Counselors available for providing you counselling for all your mental health issues.

1 Rating

Starting Price: $10/Service

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Alleva

Alleva is more than the most technologically advanced EMR in behavioral health. Our task-based, data-driven solution streamlines workflows, making compliance a breeze and improving the quality of clinical care. With built-in visualized reporting tools, operators can access their program’s health in real time. Our intuitive, user-friendly platform and customer support make life easier for clinicians so they have more time to spend time with those in their care. No need to stress about compliance—our proprietary technology ensures your charts and notes are compliant with state licensure, insurance providers, and JCAHO/CARF. Built-in AI reviews the relevant data from your notes and populates your dashboard with all the information you need at a glance. Say hello to next-level innovation.

1 Rating

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SimplePractice

SimplePractice is a comprehensive electronic health record (EHR) and practice management software tailored for health and wellness professionals. Serving over 225,000 practitioners, it offers features such as integrated telehealth, customizable documentation templates, billing and insurance tools, and a secure client portal. Designed to streamline administrative tasks, SimplePractice enhances client care and supports the growth of private practices.

Starting Price: $35.00/month/user

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Ensora Mental Health

TheraNest

For solo and small-group mental health practice owners, TheraNest is the EHR and practice-management platform that simplifies clinical documentation, streamlines billing, and empowers sustainable practice growth without administrative headaches. Unlike SimplePractice and TherapyNotes, TherapyNotes uniquely allows therapists to run secure group telehealth sessions (up to 20 participants), automatically insert evidence-based Wiley® treatment plans, and access built-in flat-rate RCM services — all in one place. TheraNest gives therapists back time, control, and confidence by combining workflow automation, AI-enhanced documentation, and reliable U.S.-based support.

Starting Price: $29 per month

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Owl Practice

Owl Practice Suite

Owl Practice is a comprehensive and compliant EHR, and practice management solution tailored specifically for mental health professionals. This innovative platform empowers practitioners to effectively engage with clients, foster growth within their practice, and streamline the payment process. With an array of features designed to simplify administrative tasks and enhance clinical workflows, Owl Practice not only helps practitioners focus more on their clients but also ensures they are well-equipped to thrive in a competitive landscape.

Starting Price: $25 per month

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Perdeca

Miznee Digital

Perdeca supports fast decision-making and decision based self-mental healthcare. Self-education sessions can be auto-generated with text from any book, article or document. Psychologists, teachers and advisors can also create fast with it. The sessions can be about any topic and in any language. Better still, sessions can be completed in a group or alone then shared and reviewed step by step. It can be accessed with a smartphone, tablet, laptop or Smart TV, regardless of the brand or operating software. Results can be shared, saved, replayed, re-used, audited and result analysis exported in PDF or CSV format. AI prediction is also featured. Key features: Any language Any subject Use multimedia content Instant web search Results analytics Easy to use Automatic outcome ranking Share result analysis and sessions steps Export analysis as PDF or CSV Create sessions in seconds Auto-generate sessions from books and other text

Starting Price: $49.00/3-month subscription

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Sanvello

Sanvello Health

Get all of the support you need to help improve your mental health—on your terms. Easily find the strategies and resources you need, day or night. With Sanvello coping tools in your pocket, managing symptoms and tracking your progress is easy. Draw strength from people who understand your situation, and share your own perspective to help others. It’s all part of being part of a community that gets it. Peer support is a powerful part of the Sanvello experience. Access expert advice at your fingertips through Sanvello Coaching. With health and wellness backgrounds and over 200 hours of Sanvello training, our coaches are ready for one-on-one or group messaging to guide and cheer you on.

Starting Price: $49.00/month/user

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HerdmanHealth

HerdmanHealth offers a smart online assessment tool to help improve the quality and consistency of mental health assessments and reports, and reduce the time and effort involved in producing them, to free counsellors up to spend more time with patients. The tool provides an online (guided in-person) questionnaire and makes it much simpler/faster for counsellors to complete and prepare the final report for mental health evaluations, so gives them more time with patients and less time filling out paperwork. It also offers an option for a patient to complete the questionnaire in their own time and place before submitting it to the counsellor for review, diagnosis and recommendations for care. By substantially reducing the administrative (documentation) burden, practitioners will be able to see more patients without compromising the quality of mental health assessments. Waiting times will be reduced and patients will receive the care they require sooner.

Starting Price: $10 per assessment

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Noteable

Noteable, LLC

Noteable is a modern, fast and reliable clinical and practice management solution for behavioral service providers. It features a full data collection and analysis suite for ABA, customizable notes and reports, automated claims generation, scheduling, invoicing, and integrated telehealth and faxing, and more. Noteable is simple to use and backed by a unique partnership model for support. Noteable partner advocates work closely with customers from the demo, through onboarding and beyond, providing responsive, competent, single-tier support and consulting. Noteable is optimized for multi-program, multi-location organizations with features that make it easy to customize business rules for each program, and track activity across locations. For ABA practitioners, the Noteable ABA Data Suite offers a mobile app for data collection with 8 collector types, that seamlessly transmits data to the cloud for analysis using advanced graphing and reporting tools.

Starting Price: $300 for the first 5 users

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Mend

Mend is an enterprise-grade patient engagement and telehealth platform designed to help healthcare organizations profitably scale their practice and care for more patients. Founded in 2014, Mend is on a mission to revolutionize healthcare delivery so that every patient can receive extraordinary care. Mend makes it easy for healthcare providers to securely and efficiently communicate with their patients and colleagues, without concerns of violating HIPAA compliance or misplacing patient information. Mend provides integrated in-office and virtual care experiences for over 100 specialties with more than 5 million patients. Mend's comprehensive platform works hand-in-hand with all major EHR and PMS software to facilitate more than 400,000 telehealth visits per month, increase patient satisfaction by up to 23%, reduce no-show rates as low as 4%, radically improve staff productivity, and help providers drive more revenue through better patient attendance.

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PIMSY Mental Health EHR

Smoky Mountain Information Systems

PIMSY is a fully certified, cloud-based electronic health record (EHR) and practice management software solution for mental and behavioral health, psychiatry, and substance usage. Created specifically for small and mid-sized clinics across the United States, PIMSY offers enterprise-grade features and the flexibility to match each organization’s unique needs in regards to note taking, authorizations, scheduling, and billing. Available both on-premises or hosted in Microsoft Azure cloud, this hybrid EHR system offers a host of features that include immunization tracking, personalized calendar, scheduler for medical professionals, electronic signature pads, and an activity feed module based on department divisions.

Starting Price: $30.00/month/user

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Best Enterprise Therapy Software

Compare the Top Enterprise Therapy Software as of April 2026

What is Enterprise Therapy Software?

Opus