Evo 2

Evo 2

Arc Institute
+
+

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About

Evo 2 is a genomic foundation model capable of generalist prediction and design tasks across DNA, RNA, and proteins. It utilizes a frontier deep learning architecture to model biological sequences at single-nucleotide resolution, achieving near-linear scaling of compute and memory relative to context length. Trained with 40 billion parameters and a 1 megabase context length, Evo 2 processes over 9 trillion nucleotides from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function prediction across multiple biological modalities, including DNA, RNA, and proteins, and to generate novel sequences with plausible genomic architecture. The model's capabilities have been demonstrated in tasks such as designing functional CRISPR systems and predicting disease-causing mutations in human genes. Evo 2 is publicly accessible via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework.

About

PyMOL is a user-sponsored molecular visualization system on an open-source foundation, maintained and distributed by Schrödinger. PyQt interface replaces Tcl/Tk and MacPyMOL on all platforms. Better third-party plugin and custom scripting support. A comprehensive software package for rendering and animating 3D structures. A plug-in for embedding 3D images and animations into PowerPoint presentations. PyMOL is a commercial product, but we make most of its source code freely available under a permissive license. The open-source project is maintained by Schrödinger and ultimately funded by everyone who purchases a PyMOL license. Open access incentive executables. Liberal evaluation policy. Improved fuse command (disallows hypervalent bonds, substitutes monovalent atoms instead of attaching to them) Properties inspector now supports unsetting settings with the “delete” key. Fix workspace disappearing on specific display resolutions.

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported

Platforms Supported

Windows Supported
Mac Supported
Linux Supported
Cloud Not Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported

Audience

Computational biologists and genetic engineers in need of a tool to model and design biological sequences across multiple modalities, enhancing research in genomics and synthetic biology

Audience

Professionals seeking a molecular visualization system for rendering and animating 3D structures

Support

Phone Support Not Supported
24/7 Live Support Not Supported
Online Supported

Support

Phone Support Not Supported
24/7 Live Support Not Supported
Online Supported

API

Offers API Not Supported

API

Offers API Not Supported

Screenshots and Videos

Screenshots and Videos

Pricing

No information available.
Free Version Not Supported
Free Trial Not Supported

Pricing

No information available.
Free Version Supported
Free Trial Not Supported

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Supported

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Not Supported

Company Information

Arc Institute
United States
arcinstitute.org/tools/evo

Company Information

PyMOL
Germany
pymol.org/2/

Alternatives

Alternatives

Evo Designer

Evo Designer

Arc Institute
Ascalaph Designer

Ascalaph Designer

Agile Molecule
ESMC

ESMC

Biohub
NAMD

NAMD

Theoretical and Computational Biophysics Group

Categories

AI Models Supported
AI Science Supported
Bioinformatics Supported
Foundation Models Supported
Molecular Modeling Supported

Categories

Molecular Modeling Supported

Integrations

Evo Designer Supported
GitHub Supported
Hugging Face Supported
Laby Not Supported
Microsoft PowerPoint Not Supported
NVIDIA BioNeMo Supported
Python Not Supported

Integrations

Evo Designer Not Supported
GitHub Not Supported
Hugging Face Not Supported
Laby Supported
Microsoft PowerPoint Supported
NVIDIA BioNeMo Not Supported
Python Supported
Claim Evo 2 and update features and information
Claim Evo 2 and update features and information
Claim PyMOL and update features and information
Claim PyMOL and update features and information