Alternatives to PyMOL
Compare PyMOL alternatives for your business or organization using the curated list below. SourceForge ranks the best alternatives to PyMOL in 2025. Compare features, ratings, user reviews, pricing, and more from PyMOL competitors and alternatives in order to make an informed decision for your business.
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1
SYNTHIA Retrosynthesis Software
Merck KGaA
Expert-coded by chemists and engineered by computer scientists, SYNTHIA™ Retrosynthesis Software enables scientists to quickly find and easily navigate innovative and novel pathways for novel and published target molecules. Quickly and efficiently scan hundreds of pathways to help you identify the best option according to your needs. Explore the most cost-effective routes to your target molecules with state of the art visualization and filtering options. Easily customize search parameters to eliminate or promote reactions, reagents or classes of molecules. Explore unique and innovative syntheses that may be unknown for building your desired molecule. Easily generate a list of commercially available starting materials for your synthesis. Benefit from ISO/IEC 27001 Information Security Certification to guarantee the confidentiality, integrity, and protection of your data.Starting Price: €0 / 30 days -
2
Avogadro
Avogadro
Avogadro is an advanced molecule editor and visualizer designed for cross-platform use in computational chemistry, molecular modeling, bioinformatics, materials science, and related areas. It offers flexible high quality rendering and a powerful plugin architecture. Avogadro is a free, open-source molecular editor and visualization tool, designed for use on Mac, Windows, and Linux in computational chemistry, molecular modeling, bioinformatics, materials science, and related areas. It offers flexible high quality rendering and a powerful plugin architecture. -
3
Ascalaph Designer
Agile Molecule
Ascalaph Designer is a general-purpose program for molecular dynamic simulations. Under a single graphical environment are represented as their own implementation of molecular dynamics as well as the methods of classical and quantum mechanics of popular programs. Molecular geometry optimization with conjugate gradient methods. Shows molecular models in separate windows. Each window has two cameras, which allow the model to be simultaneously visualized from two sides and in different graphic modes. The subwindow can be opened by dragging the splitter in the right corner of each graphical window. Clicking on an atom or bond with the left mouse button slightly changes their color and a brief info about the picked object appears in the status bar. The wire-frame style is convenient for large molecules, particularly, proteins. Drawing is very fast for this style. Finally, CPK wire frame combines the properties of several above styles.Starting Price: Free -
4
ArgusLab
ArgusLab
ArgusLab is a molecular modeling, graphics, and drug design program for Windows operating systems. It’s getting a little dated by now, but remains surprisingly popular. To date, there are more than 20,000 downloads. ArgusLab is freely licensed. You don’t need to sign anything. You can use as many copies as you need if you are teaching a class where your students might benefit from using ArgusLab. You are not allowed to redistribute ArgusLab from other websites or sources. However, you may link to this website from your own websites if you like. A low-key effort is currently underway to port ArgusLab to the iPad. In addition, I’ve done some work with the Qt cross-platform development environment in an effort to support Mac, PC, and Linux.Starting Price: Free -
5
Swiss-PdbViewer
Swiss-PdbViewer
Swiss-PdbViewer (aka DeepView) is an application that provides a user-friendly interface allowing to analysis of several proteins at the same time. The proteins can be superimposed in order to deduce structural alignments and compare their active sites or any other relevant parts. Amino acid mutations, H-bonds, angles, and distances between atoms are easy to obtain thanks to the intuitive graphic and menu interface. Swiss-PdbViewer (aka DeepView) has been developed since 1994 by Nicolas Guex. Swiss-PdbViewer was initially tightly linked to SWISS-MODEL, an automated homology modeling server developed within the Swiss Institute of Bioinformatics (SIB) at the Structural Bioinformatics Group at the Biozentrum in Basel. However, the SWISS-MODEL web interface evolved to a point where it is now possible to use it directly for advanced modeling. Maintaining a direct interface with Swiss-PdbViewer is too complex and no longer supported. -
6
MolView
MolView
MolView is an intuitive, Open-Source web application to make science and education more awesome! MolView is mainly intended as a web-based data visualization platform. You can use MolView to search through different scientific databases including compound databases, protein databases and spectral databases, and view records from these databases as interactive visualizations using WebGL and HTML5 technologies. This web application is built on top of the JavaScript libraries and online services listed below. The Virtual Model Kit has been a source of inspiration for the birth of this project.Starting Price: Free -
7
Tox Suite
ACD/Labs
Calculate drug toxicity and safety endpoints to reduce attrition rates of molecular entities that are unlikely to succeed to nomination as a drug candidate, direct new compound synthesis, and focus animal testing requirements. -
8
ChemDoodle
iChemLabs
ChemDoodle 2D contains thousands of chemistry features, helping you produce the highest quality graphics and saving you hours of work. We spend a very long time scrutinizing the graphics output in ChemDoodle. The software automatically orients bonds in the correct directions, merges bond strokes together, places attributes in the best locations and automatically makes smart decisions that lead to the most beautiful and appealing images. Of course, you can always override the software to your preference. Every component of the graphic is fully customizable. Whether you are looking to control bond widths, arrowhead sizes or shape transparency and color; you are in control. ChemDoodle’s drawing controls are made to clearly model the atoms and bonds they manage. Copious visual feedback is provided. There are also many options for customizing the drawing tools to your preference, including for accessibility concerns.Starting Price: $12.5 per month -
9
MoluCAD
New River Kinematics
MoluCAD is a full-featured molecular modeling and visualization tool designed for Windows. It is the result of a three-year National Institutes of Health biomedical technology research project aimed at producing low-cost educational software for chemistry students. The latest version incorporates many advanced features only found in expensive workstation-based modeling packages. Ease of use, premium graphical quality, and computational robustness are the trademarks of MoluCAD. Novice users are able to quickly generate models, view them form any perspective, create reaction animations, and save all data to disk. -
10
BIOVIA Discovery Studio
Dassault Systèmes
Today’s biopharmaceutical industry is marked by complexity: growing market demands for improved specificity and safety, novel treatment classes and more intricate mechanisms of disease. Keeping up with this complexity requires a deeper understanding of therapeutic behavior. Modeling and simulation methods provide a unique means to explore biological and physicochemical processes down to the atomic level. This can guide physical experimentation, accelerating the discovery and development process. BIOVIA Discovery Studio brings together over 30 years of peer-reviewed research and world-class in silico techniques such as molecular mechanics, free energy calculations, biotherapeutics developability and more into a common environment. It provides researchers with a complete toolset to explore the nuances of protein chemistry and catalyze discovery of small and large molecule therapeutics from Target ID to Lead Optimization. -
11
MolPad
MolPad
MolPad integrates an interactive chemistry sketcher into any online learning platform. Build open questions about molecular structure and organic chemistry that go beyond just recognizing the right answer. Discover how MolPad can enrich online chemistry education by providing a low code environment for creating dynamic content and smart assessment. With MolPad, we have developed several solutions for interactive and intuitive drawing of structural formulas, enabling the student to practice with topics like chemical naming, functional groups, and Lewis structures in a digital environment. By providing smart feedback based on specific errors, the student can gain more insight than with multiple choice questions. -
12
ChemSketch
ACD/Labs
Comprehensive molecular structure drawing and naming. Draw chemical structures and communicate your science. -
13
HyperProtein
Hypercube
HyperProtein is Hypercube, Inc.'s new product focusing on the computational science associated with protein sequences. The product includes the analysis of one-dimensional protein sequences as well as the analysis of consequent three-dimensional protein structures. In particular, the relationship between sequence and structure is a fundamental facet of the product. Unlike individual software programs that provide capability for some aspect of protein sequence or structure, such as sequence alignment, HyperProtein puts together a multitude of Bioinformatics and Molecular Modeling tools related to the science that initiates with a protein sequence. -
14
BIOVIA
Dassault Systèmes
BIOVIA solutions create an unmatched scientific management environment that can help science-based organizations create and connect biological, chemical and material innovations to improve the way we live. The industry-leading BIOVIA portfolio is focused on integrating the diversity of science, experimental processes and information requirements end-to-end across research, development, QA/QC and manufacturing. Capabilities over the areas of Scientific Informatics, Molecular Modeling/Simulation, Data Science, Laboratory Informatics, Formulation Design, BioPharma Quality & Compliance and Manufacturing Analytics. BIOVIA is committed to enhancing and speeding innovation, increasing productivity, improving quality and compliance, reducing costs and accelerating product development for customers in multiple industries. Manage and connect scientific innovation processes and information across the product lifecycle. -
15
Schrödinger
Schrödinger
Transform drug discovery and materials research with advanced molecular modeling. Our physics-based computational platform integrates differentiated solutions for predictive modeling, data analytics, and collaboration to enable rapid exploration of chemical space. Our platform is deployed by industry leaders worldwide for drug discovery, as well as for materials science in fields as diverse as aerospace, energy, semiconductors, and electronics displays. The platform powers our own drug discovery efforts, from target identification to hit discovery to lead optimization. It also drives our research collaborations to develop novel medicines for critical public health needs. With more than 150 Ph.D. scientists on our team, we invest heavily in R&D. We’ve published over 400 peer-reviewed papers that demonstrate the strength of our physics-based approaches, and we’re continually pushing the limits of computer modeling. -
16
YASARA
YASARA
YASARA is a molecular graphics, modeling, and simulation program for Windows, Linux, MacOS, and Android developed in 1993, that finally makes it really easy to answer your questions. With an intuitive user interface, photorealistic graphics, and support for affordable virtual reality headsets, shutter glasses, autostereoscopic displays, and input devices, YASARA creates a new level of interaction with the 'artificial reality', that allows you to focus on your goal and forget about the details of the program. YASARA is powered by PVL (Portable Vector Language), a new development framework that provides performance way above traditional software. PVL allows you to visualize even the largest proteins and enables true interactive real-time simulations with highly accurate force fields on standard PCs, making use of GPUs if available. You can push and pull molecules around and work with dynamic models instead of static pictures.Starting Price: Free -
17
ChemDraw
PerkinElmer
Since 1985 ChemDraw® solutions have provided powerful capabilities and integrations to help you quickly turn ideas and drawings into publications you can be proud of. A chemistry communication suite, ChemOffice+ Cloud transforms your chemical drawings into chemical knowledge by facilitating the management, reporting and presenting of your Chemistry research. ChemOffice+ Cloud, is a robust, comprehensive suite, purpose-built to simplify, facilitate, and accelerate chemistry communication. The cloud-native chemistry communication suite builds on the foundations of ChemDraw Professional and adds access to a powerful set of tools to enable scientific research. The mundane task of creating reports to communicate chemical research has become much more efficient with ChemOffice+ Cloud. With powerful capabilities to search, reuse, select, and organize chemical structures and data, chemists can use ChemOffice+ Cloud to create presentation-ready PowerPoint slides and manuscripts. -
18
Chemaxon Design Hub
Chemaxon
A platform that connects scientific rationale, compound design, and computational resources. Chemaxon’s Design Hub for medicinal chemistry from analysis to prioritize ideas. Design Compounds and manage ideas within one platform. A single platform that connects scientific rationale, compound design, and computational resources. Switch from PowerPoint files to graphical and chemically searchable hypotheses that are an integral part of the compound design process. Easily work with your trusted phys-chem properties, computational models, novelty issues, or purchasable compound catalogs in a rich visual environment. Involve your CROs in the compound progression process using this secure online service. Analyze collected evidence from biological assays or experimental structural information, extract SAR, and make new hypotheses for the next optimization iteration. Store your scientific hypotheses in a “designer's ELN” (chemically aware drawing canvases). -
19
Chemaxon Marvin Pro
Chemaxon
Draw and publish chemical structures seamlessly with our web-based chemistry editor. Marvin Pro is a drawing tool that combines our chemically intelligent technology with a clean user interface. Chemists, researchers, and students can convert their thoughts into high-quality visual representations in no time. Marvin Pro handles a large number of objects, chemical structures, arrows, or texts, on a single canvas, and aligns them with precision. Chemical editors shouldn’t be complicated. With our intuitive solution, you can transform your chemical structure ideas into clear visuals. The quality of your chemical drawing should match the effort you put into your research. Marvin Pro allows you to create high-quality visuals that you can then present to your workplace. Let the Marvin Pro canvas become an extension of your mind. Add predefined templates or labels, color your structures, and insert images from external sources. You can even display the structure’s formula. -
20
ChemOffice
PerkinElmer Informatics
ChemOffice enhances scientists’ personal productivity and helps them do better science by enabling them to organize and explore their compounds, reactions and associated properties so that data can be turned into actionable information, and decisions can be made with greater confidence. ChemDraw for Excel adds chemical intelligence to Excel spreadsheets so that chemists can use Excel’s analysis, sorting and organization tools to further manipulate and enrich sets of compounds and data and explore structure-activity relationships. Chem3D generates 3D models so that chemists can view their compounds in three dimensions to assess shape and properties to maximize activity or specificity. ChemFinder is a chemically-intelligent personal database system that scientists use to organize their compounds and to search for and correlate structures with properties. -
21
Chemical Computing Group
Chemical Computing Group
Chemical Computing Group (CCG) has a strong reputation for collaborative scientific support. With offices in North America, Europe and Asia, our team of PhD-level scientists works closely with our clients, providing support, hands-on training and scientific advice on a wide range of projects. CCG continuously develops new technologies with its team of mathematicians, scientists and software engineers and through scientific collaborations with customers. -
22
Structure Elucidator
ACD/Labs
Elucidate complex structures from experimental data with the help of expert algorithms. -
23
StarDrop
Optibrium
With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modeling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. Successful compounds require a balance of many different properties. StarDrop™ guides you through this multi-parameter optimization challenge to target compounds with the best chance of success, saving you time and resources by enabling you to synthesize and test fewer compounds. -
24
Evo 2
Arc Institute
Evo 2 is a genomic foundation model capable of generalist prediction and design tasks across DNA, RNA, and proteins. It utilizes a frontier deep learning architecture to model biological sequences at single-nucleotide resolution, achieving near-linear scaling of compute and memory relative to context length. Trained with 40 billion parameters and a 1 megabase context length, Evo 2 processes over 9 trillion nucleotides from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function prediction across multiple biological modalities, including DNA, RNA, and proteins, and to generate novel sequences with plausible genomic architecture. The model's capabilities have been demonstrated in tasks such as designing functional CRISPR systems and predicting disease-causing mutations in human genes. Evo 2 is publicly accessible via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework. -
25
Evo Designer
Arc Institute
Evo Designer is an advanced tool developed by the Arc Institute, leveraging the capabilities of the Evo 2 genomic foundation model to facilitate DNA sequence generation and analysis. This platform enables users to input nucleotide sequences or specify organisms, prompting the model to generate corresponding DNA sequences. It provides comprehensive annotations of coding regions and, for prokaryotic sequences, offers 3D protein visualizations utilizing ESMFold. Additionally, Evo Designer evaluates sequences by scoring their perplexity and per-nucleotide entropy, assisting researchers in assessing sequence complexity and variability. The underlying Evo 2 model is trained on over 9 trillion nucleotides from a diverse array of prokaryotic and eukaryotic genomes, employing a deep learning architecture that models biological sequences at single-nucleotide resolution with a context window extending up to 1 million tokens. -
26
Wave Terminal
Command Line Inc
Wave is an open-source, AI-native terminal built for seamless developer workflows with inline rendering, a modern UI, and persistent sessions. Features Include: - Render almost anything in line with plugins for images, Markdown, audio/video, and more. - Edit code quickly with the same editor that powers VSCode locally and remotely. - Persistent sessions, searchable universal history, and workspaces across local and remote sessions. - Native AI integration with ChatGPT, with plans to allow users to bring their own AI (BYOLLM) in the future. - Licensed under the Apache 2.0 license, with packages available for both macOS and Linux.Starting Price: $0 -
27
OGRE
OGRE
Since 2001, OGRE has grown to become one of the most popular open-source graphics rendering engines, and has been used in a large number of production projects, in such diverse areas as games, simulators, educational software, interactive art, scientific visualisation, and others. OGRE supports Windows (all major versions), Linux, OSX, Android, iOS, Javascript (via EMScripten), Windows Phone (Sponsored by Microsoft) and WinRT. Also, OGRE was ported to PS3 and Xbox360 for several titles. Ogre is released under the MIT License, which is a permissive open source license. The only condition is that you distribute the license text included in our distribution with any software that uses OGRE. Learn OGRE using our series of introducatary Tutorials. Of course the OGRE team provides official documentation in form of the OGRE Manual and API documentation. -
28
OpendTect
dGB Earth Sciences
OpendTect software consists of two parts: a free, open-source part and a commercial, closed-source part that is protected by FlexNet license managing software. The open-source part is OpendTect, a seismic interpretation software system for 2D and 3D seismic data, and for fast-track development of innovative interpretation tools. OpendTect can be extended with free plugins. The closed source part is OpendTect Pro, an extended version with extra functionality for professionals. OpendTect Pro can be further extended with commercial plugins that enable unique seismic interpretation workflows. -
29
Extism
Dylibso
Extism is an open-source, universal plug-in system to make all software programmable, and it's powered by WebAssembly. In-depth documentation, constantly updated as the project grows. 15+ officially supported Host SDKs, making Extism embeddable in the most popular languages. 7+ officially supported PDKs, to write plug-ins in whichever language a developer would like. A growing set of runtime features makes Extism an excellent plug-in system for apps of all types & sizes. Fully-featured canonical reference demo with Elixir host SDK, and plugins in Rust, TypeScript, & Javascript. Implementation of a turn-based multiplayer game platform and games included to play and review. Games are implemented as WebAssembly modules containing a specific set of exports. Check out the source code on GitHub, download the installer, and get started. 100% open-source code. Fork it, experiment, & run your own game server.Starting Price: Free -
30
OpenToonz
DWANGO
Based on the software "Toonz", developed by Digital Video S.p.A. in Italy, OpenToonz has been customized by Studio Ghibli, and used for the creation of its works for many years. Dwango has launched the OpenToonz project in cooperation with Digital Video and Studio Ghibli. OpenToonz can be used free of charge for both commercial and non-commercial projects. Available as an open-source so that anyone can modify its source code freely. We aim to develop a new platform for connecting the academic research with cutting edge animation production. -
31
Redmineflux
Redmineflux
Redmineflux is a comprehensive project management solution and an extension of the open-source Redmine, which includes over 18 plugins and 2 themes to enhance Redmine's core capabilities. -
32
DIA
DIA Association
DIA (Decentralised Information Asset) is an open-source oracle platform that enables market actors to source, supply and share trustable data. DeFi applications are reliant on trustable and scalable data feeds to build reliable products and avoid exploitation and manipulation. DIA leverages crypto-economic incentives and the wisdom of the community to source, validate and deliver trusted financial data. Bounties for data sourcing and data validation get funded with DIA tokens and are completed for reward. All data is pulled from primary sources to DIA servers. The DIA database gets hashed on-chain, and all scraper code and documentation is hosted on Github. All data is accesible via API endpoints or Oracles. Lending platforms, index providers, prediction markets and other users can freely acces DIA’s open-source, validated data streams. -
33
Tamanu
Beyond Essential Systems
Tamanu is a free and open-source EHR for low-resource and remote settings. Built around five fundamental principles outlined below, users also experience ongoing, active software development by a dedicated, full-stack team. Highly experienced delivery team, zero cost licensing, with optional service level agreements. An international community of support, and an intuitive, modern, flexible interface. Contribute to the global development community, with the security of no one ‘owning’ your code. Out-of-the-box for inpatients, outpatients, and community, no 3rd-party plug-ins needed. HL7 FHIR is compliant. Integrates with mSupply, mSupply Mobile, Tupaia, and DHIS2. ICD-10, GS1 compatible. Work online or offline with no limits, syncing whenever the internet is available, and no latency. Industry-standard encryption protocols, powerful security features, fit-for-purpose. At the hospital level, a desktop-enabled version allows a full suite of functionality.Starting Price: $35 per month -
34
3Delight
Illumination Research
Introducing 3Delight refreshingly simple and fast. High performance production rendering software & tools with unmatched support services. Illumination Research, headquartered in Singapore, specialises in rendering solutions for the demanding environment of the VFX and animation production pipeline. 3Delight was first introduced in 2002 and has since been used in countless feature films and commercials. Our product line include 3DelightNSI, 3Delight for Maya and 3Delight for Katana. We are also in the testing phase for a rendering service through 3Delight Cloud. 3Delight for Maya is our proprietary rendering plug-in for Autodesk® Maya®. It is easy to use by the artists, while providing all the flexibility to support the most demanding rendering pipelines. The free 3Delight comes with one full license with all the features but with a restriction to use a maximum of 12 cores for rendering on your computer.Starting Price: $30 per week -
35
Piskel
Piskel
Check a preview of your animation in real time as you draw. Adjust the frame delay on the fly. Several export modes supported. Animated GIFs for sharing, spritesheet PNG/ZIP for bigger projects etc. All the code is open-source and available on GitHub. -
36
GeoPandas
GeoPandas
GeoPandas is an open-source project to make working with geospatial data in python easier. GeoPandas extends the datatypes used by pandas to allow spatial operations on geometric types. Geometric operations are performed by shapely. Geopandas further depends on fiona for file access and matplotlib for plotting. The goal of GeoPandas is to make working with geospatial data in python easier. It combines the capabilities of pandas and shapely, providing geospatial operations in pandas and a high-level interface to multiple geometries to shapely. GeoPandas enables you to easily do operations in python that would otherwise require a spatial database such as PostGIS. GeoPandas is a community-led project written, used and supported by a wide range of people from all around of world of a large variety of backgrounds. GeoPandas will always be 100% open source software, free for all to use and released under the liberal terms of the BSD-3-Clause license. -
37
Tiny Tiny RSS
Tiny Tiny RSS
Tiny Tiny RSS is a free and open source web-based news feed (RSS/Atom) reader and aggregator. Free software, licensed under GNU GPLv3; self-hosted: control your own data and protect your privacy instead of relying on third-party services. Supports feed aggregation/syndication, keyboard shortcuts, and OPML import/export. Multiple ways to share stuff: export RSS feeds, plugins for various social sites, sharing by URL, etc. Sharing arbitrary content through tt-RSS. Plugins and themes, embedding full article content via readability and site-specific plugins, deduplication, including perceptual hashing for images, podcasts, flexible article filtering, JSON API, etc.Starting Price: Free -
38
Gcov
Oracle
Gcov is an open-source code-coverage tool.Starting Price: Free -
39
Sonatype Vulnerability Scanner
Sonatype
Sonatype’s Vulnerability Scanner is a tool designed to help developers identify security risks and compliance issues in their open-source components. It provides users with a comprehensive Software Bill of Materials (SBOM), which lists all open-source dependencies and highlights vulnerabilities and license risks. The platform offers real-time scanning and actionable insights, allowing teams to assess the severity of risks and implement fixes swiftly. With automated scans and detailed reports, Sonatype’s Vulnerability Scanner helps organizations secure their applications, manage third-party dependencies, and maintain compliance across their software environments. -
40
Echosec
Flashpoint
Anchored by Echosec, Flashpoint’s geospatial Open-Source Intelligence (OSINT) product, the Physical Security Intelligence (PSI) solution offers an extensive range of global open-source data fused with geospatial enrichments, integrated AI, and expert finished intelligence, so practitioners can understand critical events, protect executives, and safeguard physical assets. Accelerate investigations and enhance situational awareness with open-source data, intelligence expertise, analytical tools, and AI enrichments. Effortlessly filter out social media noise to extract meaningful information quickly, monitor the topics and locations that matter to your organization, and alert the right team members when relevant posts are detected. -
41
LottieFiles
LottieFiles
LottieFiles provides all the tools that you need to create, edit, test and display Lottie animations. Lottie is an open-source animation file format that’s tiny, high quality, interactive, and can be manipulated at runtime. The top 500 apps on the App store now use Lottie to engage users and enhance conversions. Welcome to the largest community of designers and developers using Lottie. An extensive, curated library of free assets awaits you. We have developed simple tools and integrations that require almost no learning curve and make shipping a Lottie fast and seamless. With our drag & drop online editor, you can customize any Lottie animation and download a ready-to-publish file. The LottieFiles plugin for Adobe After Effects lets you go with the flow without leaving the interface, so you can stay in the zone. No matter what platform you’re using, it’s easy to embed animations into your website with just a few clicks. -
42
Supercopier
Ultracopier
Supercopier is free and open-source software licensed under GPL3 that acts as a replacement for files copy dialogs. Main features include play/pause, speed limitation, on-error resume, and error/collision management.Starting Price: Free -
43
GPT4All
Nomic AI
GPT4All is an ecosystem to train and deploy powerful and customized large language models that run locally on consumer-grade CPUs. The goal is simple - be the best instruction-tuned assistant-style language model that any person or enterprise can freely use, distribute and build on. A GPT4All model is a 3GB - 8GB file that you can download and plug into the GPT4All open-source ecosystem software. Nomic AI supports and maintains this software ecosystem to enforce quality and security alongside spearheading the effort to allow any person or enterprise to easily train and deploy their own on-edge large language models. Data is one the most important ingredients to successfully building a powerful, general-purpose large language model. The GPT4All community has built the GPT4All open source data lake as a staging ground for contributing instruction and assistant tuning data for future GPT4All model trains.Starting Price: Free -
44
QGIS
QGIS
Create, edit, visualize, analyze and publish geospatial information on Windows, Mac, Linux, BSD and mobile devices. For your desktop, server, in your web browser and as developer libraries. QGIS is a user-friendly open-source Geographic Information System (GIS) licensed under the GNU General Public License. QGIS is an official project of the Open Source Geospatial Foundation (OSGeo). It runs on Linux, Unix, Mac OSX, Windows and Android and supports numerous vector, raster, and database formats and functionalities. QGIS provides a continously growing number of capabilities provided by core functions and plugins. You can visualize, manage, edit, analyze data, and compose printable maps. We also collect case studies of how people all over the world use QGIS for their GIS work. You can view combinations of vector and raster data (in 2D or 3D) in different formats and projections without conversion to an internal or common format. -
45
Siberian CMS
Siberian CMS
Smooth Open-Source CMS. Zero coding knowledge is required. iOS, Android and Webapp were created in just one go. Siberian is an open-source CMS. You are not renting an online platform, the software is yours, the apps you create are yours. You add value to your company by adding an asset to it. Also, you can transfer to your clients the rights on their apps. Allow users to book a seat, a slot, a table or anything you want, with an easy and multi-stores plug-in. The form is sent to the right store following the user's validation. Manage your appointments like a pro. It's now possible to add a complete appointment engine in your app and to manage multiple stores, services and providers from one place. You will also be able to set working hours for these stores, holidays slots and everything you would need to manage your appointments in the blink of an eye.Starting Price: €349 per month -
46
Penpot
Kaleidos
Penpot is the free open-source design tool that allows true collaboration between designers and developers. Hand-off drama disappears, thanks to features like CSS Grid, Flex Layout and the Code Inspect tab. Designers can create stunning designs, interactive prototypes, design systems at scale, while developers enjoy ready-to-use code and make their workflow easy and fast.Starting Price: Free -
47
Apache Geronimo
Apache
Apache Geronimo is an open-source set of projects that are focused on providing JavaEE/JakartaEE libraries and Microprofile implementations. We are actively delivering reusable Java EE components though. They are widely used and still actively maintained! Apache Geronimo provides libraries for the implementations of the Java EE and Jakarta EE specifications. The implementations are also focused on providing OSGi bundle metadata. The goal of XBean project is to create a plugin-based server analogous to Eclipse is a plugin-based IDE. XBean will be able to discover, download and install server plugins from an Internet-based repository. In addition, we include support for multiple IoC systems, support for running with no IoC system, JMX without JMX code, lifecycle and class loader management, and rock-solid Spring integration. Apache Geronimo hosts several Microprofile implementations. Apache Geronimo Arthur is an effort to build a thin layer on top of Oracle GraalVM.Starting Price: Free -
48
Audacity
Audacity
Free, open source, cross-platform audio software. Audacity is an easy-to-use, multi-track audio editor and recorder for Windows, macOS, GNU/Linux and other operating systems. Developed by a group of volunteers as open source. Audacity can record live audio through a microphone or mixer, or digitize recordings from other media. Import, edit, and combine sound files. Export your recordings in many different file formats, including multiple files at once. Supports 16-bit, 24-bit and 32-bit. Sample rates and formats are converted using high-quality resampling and dithering. Support for LADSPA, LV2, Nyquist, VST and Audio Unit effect plug-ins. Nyquist effects can be easily modified in a text editor – or you can even write your own plug-in. Easy editing with Cut, Copy, Paste and Delete. Also unlimited sequential Undo (and Redo) in the session to go back any number of steps. Real-time preview of LADSPA, LV2, VST and Audio Unit (macOS) effects. Plug-in Manager handles plug-in installation.Starting Price: Free -
49
OPALS
OPALS
OPALS Open-source Automated Library System is a powerful cooperatively developed, Web-based, open source program. This alternative technology provides Internet access to information databases, library collections and digital archives. Many school, college, research, business, religious and library union catalogs (that provide ILL services) use OPALS. There is no need to install software or purchase expensive computer hardware or software licenses to implement this powerful, turnkey Internet accessible system. The “total cost of ownership” of this standards-based, Web-based, feature rich software is demonstrably and undeniably sustainable. We can host and maintain OPALS on our servers or we can work with your IT colleagues to install and support it at your site. Experienced programmers and technical support staff update and maintain the program, giving this open source initiative a responsive, dependable support framework that is essential for institutions that serve the public. -
50
Janus-Pro-7B
DeepSeek
Janus-Pro-7B is an innovative open-source multimodal AI model from DeepSeek, designed to excel in both understanding and generating content across text, images, and videos. It leverages a unique autoregressive architecture with separate pathways for visual encoding, enabling high performance in tasks ranging from text-to-image generation to complex visual comprehension. This model outperforms competitors like DALL-E 3 and Stable Diffusion in various benchmarks, offering scalability with versions from 1 billion to 7 billion parameters. Licensed under the MIT License, Janus-Pro-7B is freely available for both academic and commercial use, providing a significant leap in AI capabilities while being accessible on major operating systems like Linux, MacOS, and Windows through Docker.Starting Price: Free