ESMFold2

ESMFold2

Biohub
HunyuanWorld

HunyuanWorld

Tencent
+
+

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About

ESMFold2 is the successor to ESMFold, setting a new state of the art for single-sequence structure prediction and enabling the generation of new functional proteins through searching the ESMC model’s latent space. The model predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequence, with optional multiple sequence alignment input for enhanced accuracy on challenging targets. It is designed for structure prediction using sequence and structure modalities, with ESM representations powering a series of looped folding layers and a diffusion model projecting pairwise representations to atomic-resolution predictions. ESMFold2 predicts protein structures directly from amino acid sequences and outputs comprehensive structural information, including all-atom coordinates for backbone and side chains, confidence metrics, and optional distogram predictions for detailed structural analysis.

About

HunyuanWorld-1.0 is an open source AI framework and generative model developed by Tencent Hunyuan that creates immersive, explorable, and interactive 3D worlds from text prompts or image inputs by combining the strengths of 2D and 3D generation techniques into a unified pipeline. At its core, the project features a semantically layered 3D mesh representation that uses 360° panoramic world proxies to decompose and reconstruct scenes with geometric consistency and semantic awareness, enabling the creation of diverse, coherent environments that can be navigated and interacted with. Unlike traditional 3D generation methods that struggle with either limited diversity or inefficient data representations, HunyuanWorld-1.0 integrates panoramic proxy generation, hierarchical 3D reconstruction, and semantic layering to balance high visual quality and structural integrity while enabling exportable meshes compatible with common graphics workflows.

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Audience

Structural biology researchers who need fast, high-resolution protein structure prediction from sequence for analysis, exploration, and experimental planning

Audience

Game developers and simulation creators who want to generate immersive 3D environments from text or image inputs using open source generative models

Support

Phone Support
24/7 Live Support
Online

Support

Phone Support
24/7 Live Support
Online

API

Offers API

API

Offers API

Screenshots and Videos

Screenshots and Videos

Pricing

Free
Free Version
Free Trial

Pricing

Free
Free Version
Free Trial

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Training

Documentation
Webinars
Live Online
In Person

Training

Documentation
Webinars
Live Online
In Person

Company Information

Biohub
Founded: 2016
United States
biohub.ai/models/esmfold2

Company Information

Tencent
Founded: 1998
China
github.com/Tencent-Hunyuan/HunyuanWorld-1.0

Alternatives

Alternatives

Hunyuan T1

Hunyuan T1

Tencent
HunyuanVideo

HunyuanVideo

Tencent
ESMC

ESMC

Biohub
Evo 2

Evo 2

Arc Institute
HunyuanOCR

HunyuanOCR

Tencent
HyperProtein

HyperProtein

Hypercube

Categories

Categories

Integrations

Python
Biohub
Git
PyTorch

Integrations

Python
Biohub
Git
PyTorch
Claim ESMFold2 and update features and information
Claim ESMFold2 and update features and information
Claim HunyuanWorld and update features and information
Claim HunyuanWorld and update features and information