ESMFold2

ESMFold2

Biohub
Hunyuan Motion 1.0

Hunyuan Motion 1.0

Tencent Hunyuan
+
+

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About

ESMFold2 is the successor to ESMFold, setting a new state of the art for single-sequence structure prediction and enabling the generation of new functional proteins through searching the ESMC model’s latent space. The model predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequence, with optional multiple sequence alignment input for enhanced accuracy on challenging targets. It is designed for structure prediction using sequence and structure modalities, with ESM representations powering a series of looped folding layers and a diffusion model projecting pairwise representations to atomic-resolution predictions. ESMFold2 predicts protein structures directly from amino acid sequences and outputs comprehensive structural information, including all-atom coordinates for backbone and side chains, confidence metrics, and optional distogram predictions for detailed structural analysis.

About

Hunyuan Motion (also known as HY-Motion 1.0) is a state-of-the-art text-to-3D motion generation AI model that uses a billion-parameter Diffusion Transformer with flow matching to turn natural language prompts into high-quality, skeleton-based 3D character animation in seconds. It understands descriptive text in English and Chinese and produces smooth, physically plausible motion sequences that integrate seamlessly into standard 3D animation pipelines by exporting to skeleton formats such as SMPL or SMPLH and common formats like FBX or BVH for use in Blender, Unity, Unreal Engine, Maya, and other tools. The model’s three-stage training pipeline (large-scale pre-training on thousands of hours of motion data, fine-tuning on curated sequences, and reinforcement learning from human feedback) enhances its ability to follow complex instructions and generate realistic, temporally coherent motion.

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Audience

Structural biology researchers who need fast, high-resolution protein structure prediction from sequence for analysis, exploration, and experimental planning

Audience

3D artists, game developers, animators, and creative technologists who want to quickly generate realistic 3D character motion from natural language descriptions without manual keyframing or motion-capture equipment

Support

Phone Support
24/7 Live Support
Online

Support

Phone Support
24/7 Live Support
Online

API

Offers API

API

Offers API

Screenshots and Videos

Screenshots and Videos

Pricing

Free
Free Version
Free Trial

Pricing

No information available.
Free Version
Free Trial

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Training

Documentation
Webinars
Live Online
In Person

Training

Documentation
Webinars
Live Online
In Person

Company Information

Biohub
Founded: 2016
United States
biohub.ai/models/esmfold2

Company Information

Tencent Hunyuan
Founded: 1998
China
hunyuan.tencent.com

Alternatives

Alternatives

DreamActor-M1

DreamActor-M1

ByteDance
ESMC

ESMC

Biohub
Character Creator

Character Creator

Reallusion
Evo 2

Evo 2

Arc Institute
HyperProtein

HyperProtein

Hypercube

Categories

Categories

Integrations

Biohub
Blender
GitHub
Hugging Face
Imagen3D
Maya
Python
Unity
Unreal Engine
arXiv

Integrations

Biohub
Blender
GitHub
Hugging Face
Imagen3D
Maya
Python
Unity
Unreal Engine
arXiv
Claim ESMFold2 and update features and information
Claim ESMFold2 and update features and information
Claim Hunyuan Motion 1.0 and update features and information
Claim Hunyuan Motion 1.0 and update features and information