Showing 159 open source projects for "gene"

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  • 1
    AlphaGenome

    AlphaGenome

    Programmatic access to the AlphaGenome model

    ...This repository contains client-side code, examples, and documentation to help you use the AlphaGenome API. AlphaGenome offers multimodal predictions, encompassing diverse functional outputs such as gene expression, splicing patterns, chromatin features, and contact maps. The model analyzes DNA sequences of up to 1 million base pairs in length and can deliver predictions at single-base-pair resolution for most outputs. AlphaGenome achieves state-of-the-art performance across a range of genomic prediction benchmarks, including numerous diverse variant effect prediction tasks.
    Downloads: 4 This Week
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  • 2

    GOBU

    Gene Browsing Utility

    Gene Ontology Browsing Utility (hereinafter, GOBU, pronounced as "go-boo") is a browsing and manipulating tool for Post-Pipeline genetic data, especially useful for data with GO annotations. With help of GOBU, we expect biologists and their cooperating technicians can pay less effort on common programming stuff. At the same time, GOBU provides an Extendable Architecture which guarantees the possibility of 1.
    Downloads: 0 This Week
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  • 3
    FragGeneScan
    FragGeneScan is an application for finding (fragmented) genes in short reads. It can also be applied to predict prokaryotic genes in incomplete assemblies or complete genomes. FragGeneScan was first released through omics website (http://omics.informatics.indiana.edu/FragGeneScan/) in March 2010, where you can find its old releases. FragGeneScan migrated to SourceForge in October, 2013.
    Downloads: 34 This Week
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  • 4
    Manatee is a web-based gene evaluation and genome annotation tool. Manatee can store and view annotation for prokaryotic and eukaryotic genomes.
    Downloads: 1 This Week
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  • 5
    cufCDS

    cufCDS

    Codon usage frequency (CUF) calculator of coding fasta sequences

    ...The following files are also produced: .fss, which reports the frequencies of codons used as start and stop signals .lss, which contains the list of start and stop codons of each gene. .cuf, which reports the total frequencies and the fraction of synonymous codons.
    Downloads: 0 This Week
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  • 6

    MetRFinder

    Detection of Heavy Metal Resistance Genes from Bacterial Proteomes

    ...Users can analyze single or multiple bacterial isolates through an intuitive graphical interface without requiring command-line expertise. MetRFinder automatically filters hits based on user-defined sequence identity thresholds and E-value criteria, assigns gene annotations, and generates detailed Excel reports along with summary statistics. The modular architecture supports efficient batch processing, organized output management, and reproducible analyses. Note: A detailed User Tutorial PDF is included with the software package to guide installation, database selection, analysis execution, and result interpretation.
    Downloads: 1 This Week
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  • 7
    MicroRNAs (miRNAs) are of significance in tuning and buffering gene expression. Despite abundant analysis tools have been developed in the last two decades, plant miRNA identification from next-generation sequencing (NGS) data remains challenging. Here present a user-friendly pure Java-based software package, SRICATs, which enable researchers to perform all steps of plant miRNA analysis based on convolutional neural network methods.
    Downloads: 0 This Week
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  • 8
    The RDP Classifier is a naive Bayesian classifier that can rapidly and accurately provides taxonomic assignments for bacterial and archaeal 16S rRNA sequences, fungal LSU and fungal ITS sequences, with confidence estimates for each assignment. More information and tutorials on how to install, use and retrain RDP Clasifier can be found on at https://github.com/rdpstaff/classifier and John Quensen's blog (https://john-quensen.com/). Citation: 1. Wang Q, Garrity GM, Tiedje JM, Cole JR....
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    Downloads: 216 This Week
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  • 9

    EvidentialGene

    Evidence Directed Gene Construction for Eukaryotes

    EvidentialGene is a genome informatics project, "Evidence Directed Gene Construction for Eukaryotes", to construct high quality, accurate gene sets for animals and plants, developed by Don Gilbert at Indiana University, see http://arthropods.eugenes.org/EvidentialGene/ Construction refers to the combination of classical gene prediction, and more recent gene assembly (de-novo and genome-assisted) methods.
    Downloads: 9 This Week
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  • 10
    CodonU

    CodonU

    A python project for analysis of codon usage for gene or genome analys

    With CodonU, you can now easily read, manipulate, and analyze various file formats used in this kind of analysis, and generate high-quality graphics suitable for publishing. This open-source project incorporates various statistical measures necessary for codon usage analysis, including codon adaptation index, codon bias index, Gravy score, and correspondence analysis for both nucleotide and protein sequences. Start using CodonU today and see how it can revolutionize your genomics...
    Downloads: 0 This Week
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  • 11

    BD-Func

    Bidirectional Functional Enrichment of Gene Expression Data

    BD-Func is an algorithm to predict activation or inhibition of pathways based upon gene expression patterns. If you use BD-Func, please cite: Warden C, Kanaya N, Chen S, and Yuan Y-C. (2013) BD-Func: A Streamlined Algorithm for Predicting Activation and Inhibition of Pathways. peerJ, 1:e159
    Downloads: 0 This Week
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  • 12

    Cylindrical Alignment App

    Arranges alignments in a rotating cylinder

    The Cylindrical Alignment App is the successor to Cylindrical BLAST Viewer. Similarly, it arranges search or other comparisons, against their "axis". Searches can be made by Basic Local Alignment Search Tool, ClustalW, or Gene Machine to name a few. This version does not require downloading or installing Java3D, and has more modern GUI features.
    Downloads: 1 This Week
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  • 13

    MaChIAto Example Files

    The example files of MaChIAto

    MaChIAto (Microhomology-associated Chromosomal Integration/editing Analysis tools); a comprehensive analysis software that can precisely classify, deeply analyze, correctly align, and thoroughly review the targeted amplicon sequencing analysis data obtained by various CRISPR experiments, including template-free gene knock-out, short homology-based gene knock-in, and even a new-class CRISPR methodology, Prime Editing. In this repository, we provide the example files of MaChIAto. You can use them as input of the MaChIAto and refer to the output data of MaChIAto.
    Downloads: 0 This Week
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  • 14
    CStone

    CStone

    Short-read de novo assembler that identifies chimeric contigs.

    > CStone wiki: https://sourceforge.net/p/cstone/wiki/Home/ Related Software: 1. CStone: (See wiki) 2. CSReadGen: https://sourceforge.net/projects/csreadgen/ 3. CView: https://sourceforge.net/projects/cview/ 4. ChimSim: https://sourceforge.net/projects/chimsim/ 5. TVScript: https://sourceforge.net/projects/tvscript/ 6. SeQuester: https://sourceforge.net/projects/sequester/ 7. TreeScope: https://sourceforge.net/projects/treescope/
    Downloads: 0 This Week
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  • 15

    MutaNET

    NGS Pipeline and Automated Mutation Analysis

    MutaNET comes with a next generation sequencing (NGS) pipeline that calls mutations based on paired-end NGS reads, an automated mutation analysis tool and various file converters and mergers. The mutation analysis feature considers the coding region, protein domains, regulation and transcription factor binding site information, and can be used to analyse the potential impact of mutations on antibiotic resistance.
    Downloads: 0 This Week
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  • 16
    miRDiana

    miRDiana

    MATLAB package to find the miRNAs targeting a list of genes

    To select miRNA target genes we developed software in MATLAB® (MathWorks®) called miRDiana that collects the union of mouse validated targets from the TargetScan, MicroCosm, mirTarBase and miRWalk 2.0 databases. Firstly, the software downloads each database and preprocesses by standardizing the miRNA and gene names. It strips the miRNA names from the species ids and converts the gene names to the official symbols of the National Center for Biotechnology Information (NCBI) database. Next, for each potential gene target it calculates an incidence matrix with all the miRNAs of each database targeting such gene. Finally, it builds a consensus matrix with the cases of the appearance of each miRNA in the four analyzed miRNA databases.
    Downloads: 0 This Week
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  • 17
    gsasnp2

    gsasnp2

    PubMed ID: 29562348 / DOI: 10.1093/nar/gky175

    * GSA-SNP2 is a successor of GSA-SNP (Nam et al. 2010, NAR web server issue). GSA-SNP2 accepts human GWAS summary data (rs numbers, p-values) or gene-wise p-values and outputs pathway genesets ‘enriched’ with genes associated with the given phenotype. It also provides both local and global protein interaction networks in the associated pathways. * Article: SYoon, HCTNguyen, YJYoo, JKim, BBaik, SKim, JKim, SKim, DNam, "Efficient pathway enrichment and network analysis of GWAS summary data using GSA-SNP2", Nucleic Acids Research, Vol. 46(10), e60(2018)...
    Downloads: 2 This Week
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  • 18

    Microarray assosiated motif analyzer

    Cis-element prediction tool from microarray data

    We developed a novel clustering-free method, microarray-associated motif analyzer (MAMA), to predict novel cis-acting elements based on weighted sequence similarities and gene expression profiles in microarray analyses. Simulation of gene expression was performed using a support vector machine and based on the presence of predicted motifs and motif pairs. The accuracy of simulated gene expression was used to evaluate the quality of prediction and to optimize the parameters used in this method. After optimization, MAMA accurately simulated more than 87% of gene expression. ...
    Downloads: 1 This Week
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  • 19

    COHCAP

    City of Hope CpG Island Analysis Pipeline

    COHCAP (City of Hope CpG Island Analysis Pipeline, pronounced "co-cap") is an algorithm to analyze single-nucleotide resolution methylation data (Illumina 450k methylation array, targeted BS-Seq, etc.). Please note: 1) The SourceForge version of COHCAP is no longer being updated. Please see the GitHub version: https://github.com/cwarden45/COHCAP This was the source repository for the Bioconductor version, with some changes after the decision to only provide the code through...
    Downloads: 1 This Week
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  • 20
    DEBay

    DEBay

    Deconvolutes qPCR data to estimate cell-type-specific gene expression

    DEBay: Deconvolution of Ensemble through Bayes-approach DEBay estimates cell type-specific gene expression by deconvolution of quantitative PCR data of a mixed population. It will be useful in experiments where the segregation of different cell types in a sample is arduous, but the proportion of different cell types in the sample can be measured. DEBay uses the population distribution data and the qPCR data to calculate the relative expression of the target gene in different cell types in the sample. ...
    Downloads: 1 This Week
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  • 21

    MoPAC

    The Modular Pipeline for the Analysis of CRISPR screens

    To facilitate the comparison of gene essentialities in two or more cell samples, we propose MoPAC (Modular Pipeline for Analysis of CRISPR screens), a Shiny-driven interactive tool for differential essentiality analysis in CRISPR/Cas9 screens. For installation and usage instructions please refer to the wiki page.
    Downloads: 0 This Week
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  • 22
    The OpenGEREA is a open enrichment analysis framework for gene expression regulation data analysis.
    Downloads: 0 This Week
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  • 23
    This is a Python-based efficient implementation of several semantic similarity measures. The target is to enable fast and easy calculation of similarity between proteins and genes using the Gene Ontology (GO).
    Downloads: 2 This Week
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  • 24
    DACO-algorithm

    DACO-algorithm

    A novel transcription factor complex prediction algorithm.

    Eukaryotic gene expression is controlled through molecular logic circuits that combine regulatory signals of many different factors. Complexation of transcription factors and other regulatory proteins is a prevailing and highly conserved mechanism of signal integration within critical regulatory pathways and enable to infer controlled genes as well as the exerted regulatory mechanism.
    Downloads: 0 This Week
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  • 25
    De_Lux

    De_Lux

    Deconvolution of luminescence cross-talk in microplate reader data

    An algorithm to deconvolve the luminescence cross-talk in high-throughput gene expression profiling to recover the true luminescence activity of a microplate.
    Downloads: 0 This Week
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