Search Results for "seq" - Page 4
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Showing 169 open source projects for "seq"
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Pathoscope
Predicts strains of genomes in Nextgen seq alignment file (sam/bl8)
This page is here for archival purpose. Please visit github for the latest version of the software: https://github.com/pathoscope PathoScope takes next-generation sequencing reads from a mixture sample and predicts which genomes are present. We use a Bayesian framework combined with an initial reference-based alignment to assign reads to the correct genome of origin. Pathoscope 2.0: Wiki: http://sourceforge.net/p/pathoscope/wiki/Home/... -
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iSRAP is an integrated Small RNA-seq Analysis Pipeline that aims to assess sequence quality and examine differentially expressed microRNA and other small non-coding RNAs.
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Ericscript is a computational framework to detect gene fusions from paired end RNA-seq data with high sensitity and specificity.
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Strandseq-InvertR
predicts inversions in Strand-seq data
Invert.R is a custom, R-based bioinformatic package that localizes and genotypes putative inversions in single cells. The program systematically assesses strand orientation of Strand-seq libraries using a read-based sliding window strategy to calculate Watson-Crick ratios. It assigns locale strand states based on these ratios and predicts inversions based on regional changes in strand state. The source code of this package is freely available. -
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mRIN
Assessing mRNA integrity directly from RNA-Seq data
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allim
Allelic imbalance meter (Allim), a new tool for measuring allele speci
Allim, Allelic imbalance meter, offers an integrated and user-friendly solution for measuring allele specific gene expression (ASE) within species. Allim estimates allelic imbalance in F1 hybrids. Since mapping bias is the largest problem for reliable estimates of allele specific gene expression using RNA-seq, Allim combines two different measures to account for mapping biases. First, Allim generates a polymorphism aware reference genome that accounts for the sequence variation between... -
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scell
single-cell RNA-seq analysis software
SCell is an integrated software tool for quality filtering, normalization, feature selection, iterative dimensionality reduction, clustering and the estimation of gene-expression gradients from large ensembles of single-cell RNA-seq datasets. SCell is open source, and implemented with an intuitive graphical interface. Binary executables for Windows, MacOS and Linux are available at http://sourceforge.net/projects/scell, source code and pre-processing scripts are available from https... -
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Jafaran
Fast and more random implementations of java.util.Random.
Jafaran (Java Fast Random) provides fast, and for some more random, implementations of java.util.Random, with additional nextXXX() methods, and methods to retrieve and restore state. The names of implementations contain "Conc" (for concurrent) if they are thread-safe and non-blocking, or "Seq" (for sequential) if they are not thread-safe. Also provides an implementation of Ziggurat algorithm (based on J. A. Doornik paper, 2005), used by nextGaussian() methods of the provided... -
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HeatmapGenerator is a graphical user interface software program written in C++, R, and OpenGL to create customized gene expression heatmaps from RNA-seq and microarray data in medical research. HeatmapGenerator can also be used to make heatmaps in a variety of other non-medical fields. HeatmapGenerator is peer-reviewed published software (http://www.scfbm.org/content/9/1/30). Please cite: [Khomtchouk et al.: "HeatmapGenerator: High performance RNAseq and microarray visualization software...
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Deep Sense
Web-interface Application for DE pipelines in RNA-seq studies
Deep Sense is a collection of open-source R web-interface applications designed for fast, simple and convenient comparisons and performance analyses of gene-level DE results from RNA-seq studies with 7 R/ Bioconductor DE pipelines: edgeR, DESeq, DESeq2, NOISeq, baySeq, EBSeq and SAMseq where users are allowed to adjust the appropriate settings for the threshold FDR values and the type of normalization procedures for their experimental needs. For software support and information... -
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olego
OLego – short or long RNA-seq read mapping to discover exon junction
OLego is a program specifically designed for de novo spliced mapping of mRNA-seq reads. OLego adopts a seeding and extension scheme, and does not rely on a separate external mapper. It achieves high sensitivity of junction detection by using very small seeds (12-14 nt), efficiently mapped using Burrows-Wheeler transform (BWT) and FM-index. This also makes it particularly sensitive for discovering small exons. It is implemented in C++ with full support of multiple threading, to allow fast... -
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SOAPfuse
a tool for identifying fusion transcripts from paired-end RNA-Seq data
SOAPfuse is an open source tool developed for genome-wide detection of fusion transcripts from paired-end RNA-Seq data. By comparing with previously released tools, SOAPfuse has a good performance. It is developed in perl, and only be used on linux OS. It requires about 8G memory to run whole analysis. So far, it is developed only for analysis on human being RNA-Seq data. SOAPfuse has been published as Method article in Genome Biology, please check http://genomebiology.com/2013/14/2/R12... -
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3C-analyzer
The detection of chromatin interactions
3C-analyzer is a computational method used for the detection of significant chromatin interactions from 3C-seq. -
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came
Identification of chromatin accessibility from NOMe-seq
Chromatin accessibility plays a key role in epigenetic regulation of gene activation and silencing. Open chromatin regions allow regulatory elements such as transcription factors and polymerases to bind for gene expression while closed chromatin regions prevent the activity of transcriptional machinery. Recently, nucleosome occupancy and methylome sequencing (NOMe-seq) has been developed for simultaneously profiling of chromatin accessibility and DNA methylation on single molecules. However... -
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SAT-Assembler
Scalable and accurate targeted gene assembly for large-scale NGS data
SAT-Assembler is a scalable and accurate gene assembly tool for large-scale RNA-Seq and metagenomic data. It recovers genes from gene families of particular interest to biologists with high coverage, low chimera rate, and extremely low memory usage compared with exiting gene assembly tools. Moreover, it is naturally compatible with parallel computing platforms. -
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EDDA
Experiment Design for Differential Abundance Analysis
EDDA is a tool for systematic assessment of the impact of experimental design and the statistical test used on the ability to detect differential abundance. EDDA can aid in the design of a range of common experiments such as RNA-seq, ChIP-seq, Nanostring assays, RIP-seq and Metagenomic sequencing, and enables researchers to comprehensively investigate the impact of experimental decisions on the ability to detect differential abundance. More details of EDDA can be found at Luo, Huaien et al... -
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SampleSpecificDBGenerator
Generates custom UniProt-XML databases from RNA-Seq data
SampleSpecificDBGenerator is a program that takes RNA sequencing data analysis results and translates them into protein database entries that are appended to a UniProt-XML file. This XML is condensed, meaning that much of the extraneous author information in UniProt-XMLs is removed for faster search times in Morpheus. Please cite http://pubs.acs.org/doi/abs/10.1021/acs.jproteome.5b00817. -
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HBS-tools
a set of tools for hairpin bisulfite-seq data analysis
The emerging genome-wide hairpin bisulfite sequencing technique facilitates the determination of DNA methylation fidelity and accurate methylation calling. Here we present HBS analyzer, the first command line based open-source tool to process genome-wide hairpin bisulfite sequencing data. It accepts Illumina paired-end sequencing reads as input, performs alignment to recover the original (pre-bisulfite-converted) DNA sequences and calls methylation status for cytosines on both DNA strands. -
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SplicingTypesAnno
Annotation tool for alternative splicing types by RNA-Seq data
This package annotates four major splicing types by RNA-Seq data, including intron retention, exon skipping, alternative donor site, and alternative acceptor site. As a post-processing tool for alignment files, it annotates the alternative splicing types with details at the intron or exon level. -
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SpliceJumper
A tool for splicing junction calling from RNA-Seq data
SpliceJumper is classification based splicing junction calling tool. For now, it accepts paired-end RNA-Seq reads as input, and calls out the junctions. Also do the alignment. -
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jChIP
Graphical environment for exploratory ChIPSeq data analysis
jChIP is a GUI-based Java application for ChIP-Seq data analysis. It was created to build binding profiles between proteins and loci in the genome. In addition it computes statistics of the number of loci/positions containing specified amount of tags. jChIP is able to load data in several common formats (SAM, BAM, WIG, BED, Bowtie) and download loci definitions directly from the Ensembl database. http://www.biomedcentral.com/1756-0500/7/676 -
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GenomeScanner
GenomeScanner displays tag data obtained from Chip-Seq and RNA-Seq.
The "Genome Scanner" is a program written to display tag data obtained from ChIP-Seq and RNA-Seq experiments. Programs already exist to do this job, but the research group here at NYU needed to explore different methods for scoring tag peaks and to visualize the results. "Genome Scanner" (GS) was written to be light-weight, fast and easily adapted to varied display tasks. The package also contains software to plot KM survival curves for patients based on gene expression data from tumor... -
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WigMaker
make wiggle file from bed file for ChIP-seq samples
This application takes bed file(or gzip bed, with .gz extension) as input, it creats a single file or a fold like 'wigs for xxx' in which the chromosome separated wiggle files will be saved. Users can set the wigextend value and step value for the output wig files. By default, they are 200 and 25. The application requires a lot of memory (about 2GB) -
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iMir
Integrated pipeline for HT miRNA-Seq data analysis
Processing of smallRNA-Seq data to gather biologically relevant information requires application of multiple statistical and bioinformatics tools from different sources, each focusing on a specific step of the analysis pipeline. The analytical workflow can be challenging for the continuous interventions by the operator, a critical factor when large numbers of datasets need to be analyzed at once. To allow a flexible and comprehensive analysis of smallRNA-Seq data we designed a novel modular...