Search Results for "genomics" - Page 2
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Showing 106 open source projects for "genomics"
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Lirex
A Package for Identification of Long Inverted Repeats in Genomes
...Lirex, as a cross-platform tool to identify LIRs in a genome, may assist in designing following experiments to explore the function of LIRs. Our tool can identify more LIRs than other LIR searching tools. For more details, please refer to Genomics, Proteomics and Bioinformatics 2017, 15:141-146 by Y. Wang and J.M. Huang. -
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ComplexHeatmap
Make Complex Heatmaps
ComplexHeatmap is an R/Bioconductor package by Zuguang Gu et al. designed to create highly flexible, complex, richly annotated heatmaps and related visualizations. It allows arranging multiple heatmaps, adding annotations, combining heatmaps, customizing colors, layouts, and integrating other plots. Often used in genomics/bioinformatics to show expression, methylation, etc., with sidebars, annotations, clustering, etc. Highly customizable layout: combining different heatmaps, arranging and splitting, dealing with multiple heatmap merges, combining with other plots etc. Integration with Shiny / interactive heatmaps via companion packages (InteractiveComplexHeatmap) to allow interactivity, etc. -
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sybil
A web-based software package for comparative genomics
Sybil is a web-based software package for comparative genomics -
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CELLX
Integrates expression, CNV, mutation, compound, and meta data.
CELLX is an informatics infrastructure to manage multi-dimensional genomics datasets containing expression, copy number variation, mutation, and compound sensitivity information. A browser based web page enables an accessible way to visualize, analyze, and download the database data in a pre-formatted table suitable for offline computation. CELLX is presently focused on supporting oncology precision medicine through the evaluation of preconceived hypotheses as well as unbiased, data driven hypothesis generation. ... -
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The Deep Review
A collaboratively written review paper on deep learning, genomics, etc
This repository is home to the Deep Review, a review article on deep learning in precision medicine. The Deep Review is collaboratively written on GitHub using a tool called Manubot (see below). The project operates on an open contribution model, welcoming contributions from anyone. To see what's incoming, check the open pull requests. For project discussion and planning see the Issues. As of writing, we are aiming to publish an update of the deep review. We will continue to make project... -
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CABBaGe
Classification Algorithm Based on a Bayesian method for Genomics
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A comparative synteny analysis tool for target-gene SNP marker discovery: connecting genomics data to breeding in Solanaceae * The foundation of this web source is CodeIgniter. * After setting the CodeIgniter framework, unzip it under the default home directory. The database is based on Maria DB (mysql). Download the schema and import it into the DB. Each species you want to analyze needs blast results.
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OncoIMPACT
Cancer driver prediction via integrative omics
OncoIMPACT is a model-driven approach to integrate omics profiles (genomics, transcriptomics etc.) and provides patient-specific cancer driver gene predictions. -
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AccNET
AccNET: Accessory Genome Constellation Network.
AccNET is a Perl application that presents a new way to study the accessory genome of a given set of organisms. Using the proteomes of these organisms, AccNET create a bipartite network compatible with common network analysis platforms. AccNET collects phylogenetic and functional information in a network improving the analysis capability. Networks offer a new perspective of organism organization through elements acquired by horizontal gene transfers and not constricted by hierarchical... -
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DiffCorr
an R package to analyze differential correlations biological networks
DiffCorr can explore differential correlations between different conditions in a modern post-genomics data including transcriptomics and metabolomics. DiffCorr package might prove useful for identifying various differential correlations and for detecting biomarker candidates. -
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EXCAVATOR2tool
Enhanced tool for detecting CNVs from whole-exome sequencing data
ATTENTION!!!!!ATTENTION!!!!!ATTENTION!!!!!ATTENTION!!!!! We recently published on BMC Genomics a novel software package, named XCAVATOR, for the identification of CNVs/CNAs from short and long reads whole-genome sequencing experiments (https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-017-4137-0). XCAVATOR is freely available at http://sourceforge.net/projects/xcavator/. EXCAVATOR2 is a collection of bash, R and Fortran scripts and codes that analyses Whole Exome Sequencing (WES) data to identify CNVs. ... -
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PoPoolationTE2: enables comparative population genomics of transposable elements (TE). As a major innovation PoPoolation TE2 introduces the physical pileup file which allows to homogenize the power to identify TEs and thus enables an unbiased comparison of TE abundance between samples, where samples could be pooled populations, tissues or sequenced individuals.
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PGAP
PGAP is a pipeline for pan-genome analysis.
PGAP is a pan-genomes analysis pipeline developed with Perl. It could perform five analytic functions with only one command, including cluster analysis of functional genes, pan-genome profile analysis, genetic variation analysis of functional genes, species evolution analysis and function enrichment analysis of gene clusters. -
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Acacia
A generic biodiversity database management system
...It combines the automated use of scientific names and synonyms in a species checklist with online access to geographical data and common knowledge data (morphological descriptors, genomics, ecology, vernacular names, economic uses, structured notes and conservation status) about the species. All these data can be cross-indexed to a citation list. The design and standard permits rapid customization to suit any taxonomic group. -
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EggLib
Evolutionary Genetics and Genomics Library
EggLib has moved to http://mycor.nancy.inra.fr/egglib/ since version 3.0.0. -
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bio-cargo
CARGO - Compressed ARchival for GenOmics
CARGO is a high-level framework that can semi-automatically generate software systems optimized for the compressed storage of arbitrary types of large genomic data collections. Straightforward applications of CARGO methods to compress FASTQ and SAM format archives require only a few lines of code, produce solutions that match and sometimes outperform specialized format-tailored compressors, and scale well to multi-TB datasets. -
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HotDriver is a python program that is designed to employ the Poisson statistical model to predict hotspot mutations in single amino acid level given a mutation dataset. Please refer to the README.txt to understand how to properly use HotDriver in your own study. Please contact tchen1@mdanderson.org or kchen3@mdanderson.org if you may have any questions.
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SCNVSim
SCNVSim, a tool to simulate somatic CNV and Strucuture Variants
...SCNVSim generates the genomes of a cancer cell population with detailed information of copy number status, loss of heterogeneity, and structure variation break points, which are essential for developing and evaluating somatic CNV and SV detection methods in cancer genomics studies. -
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...Visit http://www.biomedcentral.com/1471-2164/15/858/abstract for the pdf article describing the utility of iMSAT and if you use the program please cite this article as: Andersen and Mills: iMSAT: a novel approach to the development of microsatellite loci using barcoded Illumina libraries. BMC Genomics 2014 15:858.
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NGS-TOOLBOX
Handy tools to process/analyze next generation sequencing (NGS) data
...If you use the NGS TOOLBOX you for publication purposes you can cite the following methods paper: Rosenkranz D, Han CT, Roovers EF, Zischler H, Ketting RF. Piwi proteins and piRNAs in mammalian oocytes and early embryos: From sample to sequence. Genomics Data 2015 5:309-313. -
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NetView P
Population Genomics Network Analysis Pipeline
NetView P has been re-structured as a package for R and moved to GitHub: https://github.com/esteinig/netview -
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VBioindex
A Visual Tool to Estimate Biodiversity
...VBioindex serves as an easy to use interface and visually represents the results in the form of a simple chart. Reference : D.S. Yu and S. H. Yoo, VBioindex: A Visual Tool to Estimate Biodiversity, Genomics Inform. 2015 Sep; 13(3): 90–92. -
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Copy Number Explorer
Interactive Copy Number Analysis for Cancer Genomics
Deployed online at: https://arraycgh.shinyapps.io/Copy_Number_Explorer/ https://arraycgh.shinyapps.io/Copy_Number_Explorer_Survival/ Copy Number Explorer is a data mining tool for cancer researchers interested in the structural and copy number changes. Huge volumes of genomics data from nearly every cancer type are now freely available and several online databases have begun to collate and store this information. However, current tools focus on individual gene queries rather than chromosomal and region-based queries more relevant to some researchers. Copy Number Explorer creates interactive CNV frequency, GISTIC-style and breakage frequency plots from public (or your own) data. ... -
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circlize
Circular visualization in R
...It implements many types of plots using circular layouts: chord diagrams, circular heatmaps, arcs/links between sectors, genomic data visualization, etc. It provides low-level drawing functions as well as high-level functions to build complex visualizations. It’s often used in genomics, network analysis, or other fields where relationships among categories or entities can be nicely displayed in a circular fashion. Support for circular heatmaps, multiple tracks (rings), for showing multiple layers of data per sector. Good performance and stable codebase, detailed documentation including a book on usage examples. -
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Cancer Genome ExploreR is a new way to explore multidimensional cancer genomics data through a graphical user interface backed by the power of R. A prototype implementation is running here: https://arraycgh.shinyapps.io/HNSCC_explorer/
