C++ Bio-Informatics Software

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Browse free open source C++ Bio-Informatics Software and projects below. Use the toggles on the left to filter open source C++ Bio-Informatics Software by OS, license, language, programming language, and project status.

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  • 1
    Bowtie, an ultrafast, memory-efficient short read aligner for short DNA sequences (reads) from next-gen sequencers. Please cite: Langmead B, et al. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10:R25.
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    Downloads: 251 This Week
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  • 2
    The SourceForge OpenRasMol project is an adjunct to the RasMol and OpenrasMol project at http://rasmol.org. It is hoped that the SourceForge OpenRasMol project will provide a convenient focal point for active collaborative contributions.
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    Downloads: 125 This Week
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  • 3
    Systems Biology Markup Language (SBML)

    Systems Biology Markup Language (SBML)

    A file format for exchanging computational models in systems biology

    The Systems Biology Markup Language (SBML) is an XML-based description language for representing computational models in systems biology. Visit the project web site to learn more.
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    Downloads: 38 This Week
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  • 4
    MUMmer is a modular system for the rapid whole genome alignment of finished or draft sequence. This package provides an efficient suffix tree library, seed-and-extend alignment, SNP detection, repeat detection, and visualization tools.
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    Downloads: 50 This Week
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  • eProcurement Software Icon
    eProcurement Software

    Enterprises and companies seeking a solution to manage all their procurement operations and processes

    eBuyerAssist by Eyvo is a cloud-based procurement solution designed for businesses of all sizes and industries. Fully modular and scalable, it streamlines the entire procurement lifecycle—from requisition to fulfillment. The platform includes powerful tools for strategic sourcing, supplier management, warehouse operations, and contract oversight. Additional modules cover purchase orders, approval workflows, inventory and asset management, customer orders, budget control, cost accounting, invoice matching, vendor credit checks, and risk analysis. eBuyerAssist centralizes all procurement functions into a single, easy-to-use system—improving visibility, control, and efficiency across your organization. Whether you're aiming to reduce costs, enhance compliance, or align procurement with broader business goals, eBuyerAssist helps you get there faster, smarter, and with measurable results.
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  • 5
    Free DELTA

    Free DELTA

    Software tools for processing taxonomic descriptions in DELTA format

    The Free DELTA Project is a free, open-source, software alternative for a generic system to the processing of taxonomic descriptions based on the DELTA (DEscription Language for TAxonomy) format.
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    Downloads: 158 This Week
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  • 6
    vcftools
    A set of tools for working with VCF files, such as those generated by the 1000 Genomes Project. This project is migrating to github: https://vcftools.github.io/
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    Downloads: 35 This Week
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  • 7

    AMOS

    AMOS is a collection of tools for genome assembly

    AMOS is a collection of tools and class interfaces for the assembly of DNA reads. The package includes a robust infrastructure, modular assembly pipelines, and tools for overlapping, consensus generation, contigging, and assembly manipulation.
    Downloads: 13 This Week
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  • 8
    An open source framework for LC-MS based proteomics and metabolomics. OpenMS offers data structures and algorithms for the processing of mass spectrometry data. The library is written in C++. Our source code and wiki lives on GitHub (https://github.com/OpenMS/OpenMS).
    Downloads: 18 This Week
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  • 9

    OpenEEG - EEG hardware and software

    The OpenEEG project is about creating a low cost EEG device

    Working hardware has been built and is in a late beta stage. Software is also available.
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    Downloads: 13 This Week
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  • 10

    provean

    Predicting the functional effect of protein sequence variations

    PROVEAN (Protein Variation Effect Analyzer) is a software tool which predicts whether an amino acid substitution or indel has an impact on the biological function of a protein. The prediction is based on the change, caused by a variation, in the similarity of query sequence to closely related sequences collected through BLAST.
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    Downloads: 12 This Week
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  • 11
    CBFlib
    CBFLIB is a library of ANSI-C functions providing a simple mechanism for accessing Crystallographic Binary Files (CBF files) and Image-supporting CIF (imgCIF) files. The CBFLIB API is loosely based on the CIFPARSE API for mmCIF files.
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    Downloads: 21 This Week
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  • 12
    Fast and efficient 3D pharmacophore search developed by the Camacho Lab (http://smoothdock.ccbb.pitt.edu) at the University of Pittsburgh. Source code is available through the svn repository.
    Downloads: 10 This Week
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  • 13
    RasTop is a molecular graphics program intended for the visualisation of proteins, nucleic acids and small molecules based on the popular Rasmol software. The program is aimed at the rapid visualization and analysis of molecules.
    Downloads: 10 This Week
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  • 14
    CaspLab - Comet Assay Software Project Lab is a cross-platform image analysis software to measure level of DNA damage in SCGE (Single Cell Gel Electrophoresis) method called also comet assay method.
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    Downloads: 15 This Week
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  • 15
    QuteMol is a real time, high quality molecular visualizer that offers an array of innovative visual effects. QuteMol aims at improving the clarity of rendered images and at offering a better understanding of the molecular 3D shape and spatial structure.
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    Downloads: 15 This Week
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  • 16
    STochastic Engine for Pathway Simulation
    Stochastic simulator for signaling pathways occuring in biological cells. Handles reaction-diffusion processes in 3D tetrahedral meshes. Please check our new repository: https://github.com/CNS-OIST/STEPS
    Downloads: 3 This Week
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  • 17

    scalpel

    Genetic variants discovery tool

    Bioinformatics pipeline for discovery of genetic variants from NGS reads.
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    Downloads: 8 This Week
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  • 18
    A fully developed set of DNA sequence assembly (Gap4 and Gap5), editing and analysis tools (Spin) for Unix, Linux, MacOSX and MS Windows.
    Downloads: 13 This Week
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  • 19
    ProteoWizard
    ProteoWizard development moved to GitHub in 2018. The ProteoWizard Library is a set of software libraries and tools for rapid development of proteomics data analysis software. The libraries are cross-platform and built from the ground up using modern C++ techniques.
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    Downloads: 12 This Week
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  • 20
    MIRA V5 is available only on GitHub! The V4 version released here on SourceForge stay up as some automated release fetching packages rely on V4. MIRA - Sequence assembler and sequence mapping for whole genome shotgun and EST / RNASeq sequencing data. Can use Sanger, 454, Illumina and IonTorrent data. PacBio: CCS and error corrected data usable, uncorrected not yet.
    Downloads: 3 This Week
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  • 21
    The Sashimi project hosts the Trans-Proteomic Pipeline (TPP), a mature suite of tools for mass-spec (MS, MS/MS) based proteomics: statistical validation, quantitation, visualization, and converters from raw MS data to the open mzML/mzXML formats.
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    Downloads: 8 This Week
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  • 22
    An innovative GWAS procedure for studies on germplasm population and plant breeding
    Downloads: 7 This Week
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  • 23
    TinkerCell is a software for synthetic biology. The visual interface allows users to design networks using various biological "parts". Models can include modules and multiple cells. Users can program new functions using C or Python. www.tinkercell.
    Downloads: 4 This Week
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  • 24
    IBD on the Web is a statistical resource for analyzing the relationship between genetic and geographic distance using mantel testing, bootstrapping, and reduced major axis regression.
    Downloads: 6 This Week
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  • 25

    MaxBin

    An automatic tool for binning metagenomics sequences

    MaxBin is a software for binning assembled metagenomic sequences based on an Expectation-Maximization algorithm. Users could understand the underlying bins (genomes) of the microbes in their metagenomes by simply providing assembled metagenomic sequences and the reads coverage information or sequencing reads. For users' convenience MaxBin will report genome-related statistics, including estimated completeness, GC content and genome size in the binning summary page. Users could use MEGAN or similar software on MaxBin bins to find out the taxonomy of each bin after the binning process is finished. The most current version is 2.2.7. MaxBin was published on Microbiome journal (2:26)! Please cite the Microbiome paper if you use MaxBin in your work.
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    Downloads: 6 This Week
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