PermGUI is a Matlab-based software which is developed for quantifying blood-brain barrier permeability from dynamic contrast enhanced (DCE) MR images. It does it in two steps: 1) calculating T1 maps from DCE-MRI, 2) calculating permeability parameters (such as permeability coefficient Ki and plasma volume Vp) using the T1 maps based on the Patlak method. It includes features like automatic and manual selection of the arterial input function curve for deconvolution.
PermGUI can be downloaded for free from http://www.quantilyze.com/permgui .

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Cpa calculation window Permeability output window T1 map calculation Main Page

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Creative Commons Attribution License

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Registered

2012-03-07
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