Alternatives to PacBio

Compare PacBio alternatives for your business or organization using the curated list below. SourceForge ranks the best alternatives to PacBio in 2026. Compare features, ratings, user reviews, pricing, and more from PacBio competitors and alternatives in order to make an informed decision for your business.

  • 1
    Genome Analysis Toolkit (GATK)
    Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. The GATK is the industry standard for identifying SNPs and indels in germline DNA and RNAseq data. Its scope is now expanding to include somatic short variant calling and to tackle copy number (CNV) and structural variation (SV). In addition to the variant callers themselves, the GATK also includes many utilities to perform related tasks such as processing and quality control of high-throughput sequencing data and bundles the popular Picard toolkit. These tools were primarily designed to process exomes and whole genomes generated with Illumina sequencing technology, but they can be adapted to handle a variety of other technologies and experimental designs.
    Starting Price: Free
  • 2
    SeqOne

    SeqOne

    SeqOne

    SeqOne is an AI-powered genomic analysis platform designed to help molecular laboratories, clinical teams, biologists, and geneticists transform complex next-generation sequencing data into fast, precise, and actionable clinical insights to support personalized medicine diagnostics. It streamlines end-to-end genomic workflows, from raw sequencing files to variant interpretation and reporting, by automating routine pipeline tasks, integrating seamlessly with lab systems, and using advanced AI models such as DiagAI to rank and highlight disease-relevant variants with explainable scores, reducing manual effort and turnaround time. SeqOne supports germline and somatic analyses across applications, including oncology, rare and inherited diseases, and infectious disease detection, combining premium annotation databases and standardized interpretation guidelines to ensure clinical-grade accuracy within an intuitive user interface that scales via secure cloud.
  • 3
    Galaxy

    Galaxy

    Galaxy

    Galaxy is an open source, web-based platform for data-intensive biomedical research. If you are new to Galaxy start here or consult our help resources. You can install your own Galaxy by following the tutorial and choosing from thousands of tools from the tool shed. This instance of Galaxy is utilizing infrastructure generously provided by the Texas Advanced Computing Center. Additional resources are provided primarily on the Jetstream2 cloud via ACCESS, and with support from the National Science Foundation. Quantify, visualize, and summarize mismatches in deep sequencing data. Build maximum-likelihood phylogenetic trees. Phylogenomic/evolutionary tree construction from multiple sequences. Merge matching reads into clusters with TN-93. Remove sequences from a reference that are within a given distance of a cluster. Perform maximum-likelihood estimation of gene essentiality scores.
    Starting Price: Free
  • 4
    Illumina DRAGEN Secondary Analysis
    The Illumina DRAGEN Secondary Analysis provides accurate, comprehensive, and efficient analysis of next-generation sequencing data. Graph reference genome and machine learning driving unprecedented accuracy. Provides ultra-efficient workflow; can fully process a 34x whole human genome in ~30 minutes with DRAGEN server v4. Furthers ultra-efficient workflow by reducing FASTQ file sizes up to 5×. Analyzes next-generation sequencing (NGS) data from whole genomes, exomes, methylomes, and transcriptomes. Available on platform of choice and scalable based on needs. DRAGEN analysis leads in accuracy for germline and somatic variant calling demonstrated in industry challenges from precisionFDA. DRAGEN analysis enables labs of all sizes and disciplines to do more with their genomic data. DRAGEN analysis uses highly reconfigurable field-programmable gate array technology (FPGA) to provide hardware-accelerated implementations of genomic analysis algorithms.
  • 5
    Azenta Life Sciences

    Azenta Life Sciences

    Azenta Life Sciences

    Azenta Life Sciences offers scalable, powerful, and flexible informatics sample processing solutions that enable lab systems to efficiently deploy across all sites and utilize built-in project and diagnostic operations management functionality. We provide unrivaled sample exploration and management solutions to help you accelerate discovery, development, and delivery. Azenta Life Sciences offers cloud-based informatics solutions for sample processing that automate laboratory workflows and optimize staff workload through standardized processes. The software offers modules that manage clinical trials, families and patients, informed consent, storage, diagnostics, next-generation sequencing, and sample processing. Interfaces with external data sources and offers flexible options to integrate 3rd party systems and instruments.
  • 6
    Evo Designer

    Evo Designer

    Arc Institute

    Evo Designer is an advanced tool developed by the Arc Institute, leveraging the capabilities of the Evo 2 genomic foundation model to facilitate DNA sequence generation and analysis. This platform enables users to input nucleotide sequences or specify organisms, prompting the model to generate corresponding DNA sequences. It provides comprehensive annotations of coding regions and, for prokaryotic sequences, offers 3D protein visualizations utilizing ESMFold. Additionally, Evo Designer evaluates sequences by scoring their perplexity and per-nucleotide entropy, assisting researchers in assessing sequence complexity and variability. The underlying Evo 2 model is trained on over 9 trillion nucleotides from a diverse array of prokaryotic and eukaryotic genomes, employing a deep learning architecture that models biological sequences at single-nucleotide resolution with a context window extending up to 1 million tokens.
  • 7
    MEGA

    MEGA

    MEGA

    MEGA (Molecular Evolutionary Genetics Analysis) is a powerful and user-friendly software suite designed for analyzing DNA and protein sequence data from species and populations. It facilitates both automatic and manual sequence alignment, phylogenetic tree inference, and evolutionary hypothesis testing. MEGA supports a variety of statistical methods including maximum likelihood, Bayesian inference, and ordinary least squares, making it an essential tool for comparative sequence analysis and understanding molecular evolution. MEGA offers advanced features such as real-time caption generation to help explain the results and methods used in analysis and the maximum composite likelihood method for estimating evolutionary distances. The software is equipped with robust visual tools like the alignment/trace editor and tree explorer and supports multi-threading for efficient processing. MEGA can be run on multiple operating systems, including Windows, Linux, and macOS.
    Starting Price: Free
  • 8
    Geneyx

    Geneyx

    Geneyx

    Geneyx Analysis is a comprehensive solution for next-generation sequencing (NGS) data that can scale the process of FASTQ to clinical reports for hospital and commercial labs. This advanced platform integrates machine learning and AI-based features to identify novel biomedical insights, while also improving diagnostic yields and turnaround times. By providing a fully transparent and intuitive solution, Geneyx Analysis enables clinicians and researchers to have complete control over data analysis and alleviates the complexities of regulating in-house bioinformatics pipelines. Protocols can be fully customized to accommodate gene panels, exomes, and genomes, and our comprehensive annotation engine supports the analysis of all genetic variants including structural and copy number variations as well as regulatory elements. Together, Geneyx Analysis automates the diagnostic process from sequencer to report, while creating a comprehensive resource for novel variant discovery.
  • 9
    Genoox

    Genoox

    Genoox

    Through our diverse and growing community, Genoox accumulates the most relevant database and delivers actionable, real-world genomic insights that impact lives, improve clinical outcomes, and shape the business of healthcare. Our solutions are changing the face of genomics. Genoox uses the power of its community and combines public data with community data to streamline the path from DNA sample to clinical report, impacting patient care by making genomic data accessible and actionable at the point of care. Genoox enhances research and life sciences companies by providing an insight platform derived from real-world data and evidence and powered by our community with robust genomic analytics, helping researchers simplify complex genomic data and make impactful discoveries using the most advanced genetic tools and applications. Genoox helps biosystems companies such as DNA sequencing companies to bundle its state-of-the-art genomic engine with dedicated assays.
  • 10
    NVIDIA Parabricks
    NVIDIA® Parabricks® is the only GPU-accelerated suite of genomic analysis applications that delivers fast and accurate analysis of genomes and exomes for sequencing centers, clinical teams, genomics researchers, and high-throughput sequencing instrument developers. NVIDIA Parabricks provides GPU-accelerated versions of tools used every day by computational biologists and bioinformaticians—enabling significantly faster runtimes, workflow scalability, and lower compute costs. From FastQ to Variant Call Format (VCF), NVIDIA Parabricks accelerates runtimes across a series of hardware configurations with NVIDIA A100 Tensor Core GPUs. Genomic researchers can experience acceleration across every step of their analysis workflows, from alignment to sorting to variant calling. When more GPUs are used, a near-linear scaling in compute time is observed compared to CPU-only systems, allowing up to 107X acceleration.
  • 11
    Cellenics

    Cellenics

    Biomage

    Turn your single-cell RNA sequencing data into meaningful insight with Cellenics software. Biomage hosts a community instance of Cellenics, an open source analytics tool for single-cell RNA sequencing data that has been developed at Harvard Medical School. It enables biologists to explore single-cell datasets without writing code and helps scientists and bioinformaticians to work together more effectively. It takes you from count matrices to publication-ready figures in just a few hours and can be integrated seamlessly with your workflow. It’s fast, interactive, and user-friendly. And it’s cloud-based, secure, and scaleable. The Biomage-hosted community instance of Cellenics is free for academic researchers with small/medium-sized datasets (up to 500,000 cells). It’s used by 3000+ academic researchers studying cancer, cardiovascular health, and developmental biology.
    Starting Price: Free
  • 12
    g.nome

    g.nome

    Almaden Genomics

    g.nome, a cloud-native platform that delivers streamlined, scalable, and interoperable workflows for next-generation sequencing analysis. g.nome provides a low-code/no-code pipeline build. With pre-built workflows and toolkits from a curated library, g.nome is giving power to researchers — enabling them to import custom code, handle big datasets reliably, and optimize team collaboration from anywhere. With g.nome, long-time barriers linked to workflow language, process flow visibility, and quality control are removed. All that’s left are streamlined, scalable, and interoperable genomic workflows — leaving research teams to do what they do best: focus on the science.
  • 13
    XIFIN LIS
    The award-winning XIFIN LIS is a fully scalable SaaS-based laboratory information system that offers multi-specialty workflows, a comprehensive toolset, flexible and secure connectivity and leading-edge capabilities that optimize high volume and complex testing labs. In response to value-based and patient-centered coordinated care models, the healthcare industry is shifting. Accelerating the shift is the exponential growth in the adoption of genomic testing and personalized medicine using next-generation sequencing (NGS). Laboratories must adapt their existing processes to meet the challenge of implementing and reporting these high complexity tests. Since diagnostic insights have the potential to reduce overall healthcare costs and improve patient care – it is crucial that laboratories better integrate with the healthcare ecosystem. These demands are driving the need for more interaction and greater communication across all healthcare and diagnostic providers.
  • 14
    Partek Flow
    Partek bioinformatics software delivers powerful statistical and visualization tools in an easy-to-use interface. Researchers of all skill levels are empowered to explore genomic data quicker and easier than ever before. We turn data into discovery®. Pre-installed workflows and pipelines in our intuitive point-and-click interface make sophisticated NGS and array analysis attainable for any scientist. Custom and public statistical algorithms work in concert to easily and precisely distill NGS data into biological insights. Genome browser, Venn diagrams, heat maps, and other interactive visualizations reveal the biology of your next-generation sequencing and array data in brilliant color. Our Ph.D. scientists are always just a phone call away and ready to help with your NGS analysis any time you have questions. Designed specifically for the compute-intensive needs of next-generation sequencing applications with flexible installation and user management options.
  • 15
    BaseSpace Sequence Hub
    Data management and simplified bioinformatics for labs getting started and for rapidly scaling next-generation sequencing (NGS) operations. As a key component of the BaseSpace Suite, BaseSpace Sequence Hub is a direct extension of your Illumina instruments. Encrypted data flow from the instrument into BaseSpace Sequence Hub, enabling you to manage and analyze your data easily with a curated set of analysis apps. BaseSpace Sequence Hub is powered by Amazon Web Services (AWS). Offers a security-first environment. Enables you to set up runs and monitor instrument run quality. Promotes efficiency by converting sequencing data to a standard format and streaming directly to the cloud. Provides access to computing resources without the capital expenditure of in-house infrastructure. Increases organizational productivity with easy access to a multitude of genomic analysis apps (provided by you, Illumina, or third parties).
  • 16
    Geneious

    Geneious

    Geneious

    Geneious Prime makes bioinformatics accessible by transforming raw data into visualizations that make sequence analysis intuitive and user-friendly. Simple sequence assembly and easy editing of contigs. Automatic annotation for gene prediction, motifs, translation, and variant calling. Genotype microsatellite traces with automated ladder fitting and peak calling and generates tables of alleles. Beautiful visualizations of annotated genomes and assemblies are displayed in a highly customizable sequence view. Powerful SNP variants analysis, simple RNA-Seq expression analysis, and amplicon metagenomics. Design and test PCR and sequencing primers and create your own searchable primer database. Geneious Biologics is a flexible, scalable, and secure way to streamline your antibody analysis workflows, create high-quality libraries and select the optimal therapeutic candidates.
    Starting Price: $1,280 per year
  • 17
    Emedgene

    Emedgene

    Illumina

    Emedgene streamlines your tertiary analysis workflows for rare disease genomics and other germline research applications. Emedgene is designed to accelerate the time and certainty in user-defined variant interpretation, prioritization, curation, and research report generation. Enable greater efficiency from your tertiary analysis workflows with explainable AI (XAI) and automation supporting genomes, exomes, virtual panels, and targeted panels. Unify your laboratory and NGS instrumentation with your IT systems to simplify and secure your complete workflow. Confidently keep pace with evolving science, technology, and demand with up-to-date knowledge graph options, curation capabilities, and a team of experts to support your journey. Increase throughput without increasing headcount using explainable AI (XAI) and automated workflows. Implement a high throughput WGS, WES, virtual panel, or targeted panel workflow that is integrated into your lab's digital ecosystem.
  • 18
    DNAnexus Titan
    DNAnexus Titan™ powers the future of genomics research and clinical pipelines with trusted, high-performance data analysis solutions. Legacy informatics tools were not designed to manage today's higher volumes of sequencing data. With home-grown, do-it-yourself systems, research centers and clinical diagnostic testing companies are finding it difficult and time-consuming to create, refine, validate, and execute pipelines at scale. DNAnexus Titan™ removes bottlenecks in development and production with a unified platform that brings all your data and pipelines together in one place and delivers unparalleled efficiencies. Leave the heavy lifting of managing industry and region-specific security and compliance requirements to us, while meeting the growing global demand for sequencing data.
  • 19
    Tempus

    Tempus

    Tempus

    Tempus AI is a leading health technology company headquartered in Chicago, Illinois. Specializing in artificial intelligence and precision medicine, Tempus aims to revolutionize patient care by leveraging data and AI to develop personalized treatment plans across various medical fields, including oncology, cardiology, radiology, and depression. The company's comprehensive platform integrates genomic sequencing, clinical data, and AI-driven analytics to provide actionable insights for healthcare providers and researchers. We deliver a comprehensive view of your patients through our tissue and liquid tests, DNA and RNA sequencing, somatic and germline tests, tumor-normal matched profiling, and MRD and monitoring test options. We offer a fast, reliable platform for ordering Tempus tests, accessing patient insights, and utilizing our AI-driven technologies seamlessly. The first generative AI-enabled clinical assistant that provides access to patient insights directly at your fingertips.
  • 20
    Evo 2

    Evo 2

    Arc Institute

    Evo 2 is a genomic foundation model capable of generalist prediction and design tasks across DNA, RNA, and proteins. It utilizes a frontier deep learning architecture to model biological sequences at single-nucleotide resolution, achieving near-linear scaling of compute and memory relative to context length. Trained with 40 billion parameters and a 1 megabase context length, Evo 2 processes over 9 trillion nucleotides from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function prediction across multiple biological modalities, including DNA, RNA, and proteins, and to generate novel sequences with plausible genomic architecture. The model's capabilities have been demonstrated in tasks such as designing functional CRISPR systems and predicting disease-causing mutations in human genes. Evo 2 is publicly accessible via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework.
  • 21
    Platforma

    Platforma

    MiLaboratories

    Platforma is a no-code bioinformatics software that converts raw next-generation sequencing (NGS) data into insights. It offers a user-friendly interface with modular, no-code "blocks" for complex analysis tasks like immune repertoire, single-cell, and gene expression data. Building on the legacy of its predecessor, MiXCR, Platforma also enables AI-powered selection for antibody/TCR candidates. The platform is designed to be accessible to scientists without a bioinformatics background, allowing for scientists to take control of their own discoveries and reduce time to insight.
  • 22
    OpenFreezer

    OpenFreezer

    OpenFreezer

    OpenFreezer laboratory reagent tracking and workflow management system is an open-source information management system for biological laboratories. The system tracks information on all reagents within the laboratory, including specific properties of each reagent (i.e. sequences, external identifiers), and on all the physical preparations of these reagents (storage locations, physical characteristics). Complementing this repository are workflow tools, such as primer design and automated feature mapping, making OpenFreezer a valuable tool for the bench scientist. It comprises a variety of software tools designed to provide support to wetlab scientists. At its core, the system tracks information on all reagents within the laboratory, such as types of reagents, specific properties of each reagent (including sequences), all isolates and preps of a reagent, and where the preps of reagents are stored in the laboratory.
  • 23
    Biohub

    Biohub

    Biohub

    Biohub is an open platform for building on the world model of protein biology. It provides access to the ESM family of models, including ESMC, ESMFold2, and ESM3, along with interactive tools and developer resources for protein science research. ESMC is a state-of-the-art protein language model trained on billions of evolutionary sequences, building representations that capture fundamental mechanisms of protein structure and function. It powers functional analysis, structure prediction, protein design, and the exploration of evolutionary relationships between proteins. ESMFold2 predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequence, with optional multiple sequence alignment input for enhanced accuracy on challenging targets. ESM3 jointly models sequence, structure, and function, enabling controllable generation of novel proteins by conditioning on any combination of these modalities.
  • 24
    Kanteron

    Kanteron

    Kanteron Systems

    Kanteron Platform ingested medical images, digital pathology slides, genomics sequences, and patient data from modalities, scanners, sequencers and databases, and provided a complete data toolkit to every team in hospital networks. Pharmacogenomics for adverse medication event prevention, and Precision Medicine application at the point of care: Incorporates sources of drug-gene interaction data that were previously only available in in accessible formats (e.g. tables in a PDF document), implementing the major Pharmacogenomic databases (like PharmGKB, CGI, DGIdb, OpenTargets...) Allows the user to refine their query to certain gene families, types of interactions, classes of drugs, etc. Flexible AI means you can choose the data set that best fits your use case, and apply it to your relevant medical images.
  • 25
    HyperProtein

    HyperProtein

    Hypercube

    HyperProtein is Hypercube, Inc.'s new product focusing on the computational science associated with protein sequences. The product includes the analysis of one-dimensional protein sequences as well as the analysis of consequent three-dimensional protein structures. In particular, the relationship between sequence and structure is a fundamental facet of the product. Unlike individual software programs that provide capability for some aspect of protein sequence or structure, such as sequence alignment, HyperProtein puts together a multitude of Bioinformatics and Molecular Modeling tools related to the science that initiates with a protein sequence.
  • 26
    QIAGEN CLC Genomics Workbench

    QIAGEN CLC Genomics Workbench

    QIAGEN Digital Insights

    QIAGEN CLC Genomics Workbench is a powerful solution that works for everyone, no matter the workflow. Cutting-edge technology and unique features and algorithms widely used by scientific leaders in industry and academia make it easy to overcome challenges associated with data analysis. User-friendly bioinformatics software solutions allow for comprehensive analysis of your NGS data, including de novo assembly of whole genomes and transcriptomes, resequencing analysis (WGS, WES and targeted panel support), variant calling, RNA-seq, ChIP-seq and DNA methylation (bisulfite sequencing analysis). Analyze your RNA-seq and small RNA (miRNA, lncRNA) data with easy-to-use transcriptomics workflows for differential expression analysis at gene and transcript levels. QIAGEN CLC Genomics Workbench is developed to support a wide range of NGS bioinformatics applications.
  • 27
    GenomiX

    GenomiX

    VE3 Global

    GenomiX is a unified analytics platform built to manage the complexity of modern genomics research and clinical workflows. It supports large-scale sequencing data, integrates fragmented systems like LIMS and EHRs, and enables multi-omics analysis across DNA, RNA, and epigenetics. With its cloud-agnostic, container-native architecture, GenomiX ensures flexibility, compliance, and scalability for both research and healthcare environments. The platform streamlines workflows with support for popular engines like Nextflow, WDL, and Snakemake, while offering preconfigured bioinformatics pipelines. Advanced AI and ML integrations accelerate clinical interpretation and research insights. GenomiX also prioritizes security, ensuring GDPR, HIPAA, and NHS compliance while facilitating collaboration across institutions.
  • 28
    XetaBase

    XetaBase

    Zetta Genomics

    The unique XetaBase platform simplifies tertiary analysis, aggregating, indexing, and enriching secondary genomic data, enabling continual re-interpretation to unlock research and clinical insight. XetaBase accelerates data management and the cost-effective application of genomic data in the lab and clinic. XetaBase encompasses genomic scale, the greater the volume and complexity, the greater the insight and outcomes. XetaBase is a genomic-native technology, built on the open-source, OpenCB software platform to meet the scale, speed, and re-interpretation demands of genomic medicine. Zetta Genomics delivers genomic data management fit for the precision medicine age. XetaBase is a completely novel solution to the challenges of genomic data. It sweeps away obsolete flat file approaches to bring meaningful and actionable genomic data into the lab and the clinic. XetaBase empowers continual re-interpretation while scaling seamlessly as databases grow to encompass genome sequences.
  • 29
    Phenix

    Phenix

    Phenix

    Phenix planning and scheduling software uses Aligned Product Wheels™ to optimize changeovers and inventory, and align production with the business’s customer service, cost and working capital goals. Schedules determine the sequence and timing of the production of hundreds or thousands of different products across multiple production lines. Correct production sequences minimize changeover costs. Every out of sequence product complicates the changeover and wastes time and money. Correct cycle times balance changeover and inventory costs. Cycles that are too short or too long cause customer service and inventory problems.Volatile demand, erratic supply, and internal plant and staffing problems force schedulers to frequently deviate from plan and reschedule. Phenix product wheels assign product families to lines and optimize the production sequence to minimize changeover loss.
  • 30
    Parse Biosciences Evercode
    Combinatorial barcoding technology strips away the limitations and frustrations of yesterday’s single-cell approach. It ditches the specialized instrument, freeing you to pursue unprecedented discoveries. Unleash the potential of a single cell. Profile from 1000 to 1 million cells or nuclei in a single experiment, offering unparalleled scientific progress. Evercode combinatorial barcoding technology blows droplet-based approaches out of the water. Expand the size of your experiments without the limitations of yesterday’s restraints. Get better data quality. All without the need for finicky hardware that’s already out of date. Perform single-cell experiments with nothing more than a pipette and common laboratory equipment. Split-pool combinatorial barcoding enables scalable single cells without any custom instrument. Scalable single-cell sequencing without the instrument. Each kit provides end-to-end solution reagents and intuitive analysis software.
  • 31
    Inspirata

    Inspirata

    Inspirata

    Inspirata is an oncology-focused technology platform designed to optimize cancer service lines through accurate data reporting and operational efficiency. It helps healthcare organizations improve quality of care while driving revenue growth by unlocking the full value of oncology data. Inspirata uses advanced AI and automation to ensure timely, complete, and compliant cancer reporting for state and federal requirements. The platform enables real-time access to structured patient data to support research, discovery, and clinical trials. Automated casefinding and data abstraction reduce registry workload while improving accuracy. Inspirata also enhances patient navigation from diagnosis through survivorship. Overall, it empowers cancer programs to deliver better outcomes with lower operational costs.
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    Clarity LIMS
    Clarity LIMS is a laboratory information management system designed for genomics labs to track samples and manage workflows for an optimized and efficient lab. Clarity LIMS does much more than track samples. As the digital backbone of the lab, it actively manages your entire laboratory operations, from sample and data management to people, instruments, and consumables. Clarity LIMS standardizes and automates workflows, saving time and reducing the chance of human errors. It scales with your laboratory ecosystem to accommodate new technologies and workflows. Clarity LIMS: Helps your laboratory reduce time with straightforward implementation, prepackaged workflows for Illumina sample/library prep kits and instruments, and quality control features that flag poor-quality samples Helps support compliance with eSignature, audit trails, reagent and lot tracking, and privacy and security controls Promotes accuracy with automation and built-in business logic and error checking
  • 33
    ProximaX

    ProximaX

    ProximaX

    A developer-friendly and enterprise-ready stack of distributed and decentralized technologies. The ProximaX Sirius platform consists of multiple servers distributed in a network. It follows a “hub and spoke” design where the core component is the blockchain, or the “hub,” and the other components are service layers, or “spokes”. The service layers consist of P2P and distributed storage, streaming, database, and supercontract where all storage, messaging, and transactions are encrypted. Streaming includes text, video, and voice data. Additional service layers can be added to ProximaX Sirius to offer more functionalities. These layers may be anything from specialized services such as artificial intelligence to distributed computing for genome sequencing. With the expansion of service layers, however, the performance of individual layers remains unaffected. This is similar to multiple sets of network server nodes running in parallel and held together by the blockchain at the core.
  • 34
    XenData

    XenData

    XenData

    We are a global provider of cutting-edge data storage solutions optimized for creative video, medical imaging, video surveillance and other applications with high volumes of large files. We provide active archive systems based on LTO data tape and hybrid cloud. Our LTO archives scale to 100+ Petabytes and provide cost-effective, secure, long-term retention of file-based assets. When configured as private cloud storage, our LTO solutions provide an attractive alternative to public cloud storage services, such as AWS Glacier and the Archive Tier of Azure object storage. In addition, we offer cloud-based synchronization services that provide file sharing across multiple locations and create a global file system. This boosts the productivity of distribute teams by enabling them to seamlessly share and synchronize files across all locations. The reduced cost of sequencing means that requirements for genomic data storage are exploding.
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    ESMC

    ESMC

    Biohub

    ESMC is the latest in the ESM family of protein language models, establishing a new frontier in representation learning for protein biology. Trained on billions of evolutionary sequences, it learns representations that reflect a mechanistic reduction of protein structure and function. The model is built on a transformer architecture, supports sequences as its core modality, and is trained on up to 6 billion proteins. ESMC is designed for protein science research, including structure prediction, function annotation, protein design, and understanding evolutionary relationships between proteins. It can generate novel proteins from partial sequence, structure, or functional constraints, helping researchers explore new possibilities in protein design and biological discovery. The Biohub Platform provides access to ESMC through the API and the ESM Python package, with quickstart resources for installing the package, creating an API key, connecting to the platform.
    Starting Price: Free
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    RestSequence
    RestSequence is a no-code platform that allows users to create end-to-end product test workflows by using underlying product-under-test APIs. It enables users to create, manage, and execute test cases and scenarios efficiently. By harnessing the power of their application's Swagger API collection, RestSequence empowers users to quickly design and test scenarios, guaranteeing superb application performance and reliability. With RestSequence, you can onboard generated test scenarios, integrate them into your CI/CD pipeline, and run them on nightly, weekly, or release builds. The best part is that the output file generated once using RestSequence can be used for future testing scenarios without making any changes. RestSequence reads and parses API details (method, URL, payload, request body, etc.) from a Swagger specification file. It tests each API endpoint for correct responses, status codes, required fields, and invalid data, tracking the created resources during test execution.
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    SeeHash Laboratory ERP
    A Laboratory ERP is software that allows you to effectively manage samples and associated data. By using an ERP, your lab can automate workflows, integrate instruments, and manage samples and associated information. Additionally, you can produce reliable results more quickly and can track data from sequencing runs over time and across experiments to improve efficiency.
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    ESMFold2

    ESMFold2

    Biohub

    ESMFold2 is the successor to ESMFold, setting a new state of the art for single-sequence structure prediction and enabling the generation of new functional proteins through searching the ESMC model’s latent space. The model predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequence, with optional multiple sequence alignment input for enhanced accuracy on challenging targets. It is designed for structure prediction using sequence and structure modalities, with ESM representations powering a series of looped folding layers and a diffusion model projecting pairwise representations to atomic-resolution predictions. ESMFold2 predicts protein structures directly from amino acid sequences and outputs comprehensive structural information, including all-atom coordinates for backbone and side chains, confidence metrics, and optional distogram predictions for detailed structural analysis.
    Starting Price: Free
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    ROCKITPLAY

    ROCKITPLAY

    DacsLabs

    ROCKITPLAY delivers data differently than a standard game download or file load. Instead of downloading files in an arbitrary sequence, ROCKITPLAY sequences data based on real user gameplay, so that the data blocks that are required in the first minutes of gameplay are delivered first. FastStart downloads can start a game with as little as 1% downloaded. ROCKITPLAY dynamically adjusts the time to start based on the game and available user bandwidth. Start playing games up to 200x faster while downloading. Reduce patch sizes by up to 50% saving bandwidth and costs. Increase reading speed of HDD to greater than SSD speed. Based on real user behavior the system intelligently predicts required data blocks in order to start the game during download. With ROCKITPLAY, the game is being downloaded in data-sequenced order, so at the end you have a full, standard game install. Data remains sequenced even on your local drive, significantly improving game boot and loading time.
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    GPT-Rosalind
    GPT-Rosalind is a purpose-built frontier reasoning model developed by OpenAI to accelerate scientific research across biology, drug discovery, and translational medicine. It is designed specifically for life sciences workflows, where researchers must navigate large volumes of literature, experimental data, and specialized databases to generate and validate new ideas. It combines deep domain understanding in areas such as chemistry, genomics, protein engineering, and disease biology with advanced tool-use capabilities, allowing it to interact with scientific databases, analyze experimental outputs, and support complex, multi-step reasoning tasks. It can assist with evidence synthesis, hypothesis generation, literature review, sequence interpretation, and experimental planning, helping scientists move faster from raw data to actionable insights. GPT-Rosalind transforms complex, time-intensive research processes into more efficient AI-assisted workflows.
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    Orbit BioSequence
    Orbit BioSequence by Questel is a powerful IP intelligence software specifically designed to help researchers, patent professionals, and biotech companies analyze and manage biological sequence data within the intellectual property (IP) landscape. It offers an advanced solution for searching, analyzing, and monitoring nucleotide and protein sequences found in patent documents, giving users unprecedented access to sequence information critical for innovation and competitive analysis. Orbit BioSequence allows users to perform highly accurate similarity and identity searches across global patent databases, helping organizations identify existing patents, avoid infringement risks, and uncover licensing or partnership opportunities. It also integrates cutting-edge search algorithms and curated datasets to ensure precision and relevance in search results.
  • 42
    Universal Analysis Software (UAS)
    Universal Analysis Software (UAS) provides a platform for analyzing and managing forensic genomic data, simplifying complex bioinformatics. The UAS is an all-inclusive solution, containing analysis modules supporting all current ForenSeq workflows including ForenSeq MainstAY, ForenSeq Kintelligence, ForenSeq DNA Signature Prep, ForenSeq mtDNA Whole Genome, and ForenSeq mtDNA Control Region. UAS rapidly generates FASTQ files, performs alignment, and calls forensically relevant variants from NGS data. Extensive testing backs highly reliable variant calls to deliver accurate results in a user-friendly package with no per-seat licenses. Designed specifically for forensic analysts, UAS streamlines handling of base-by-base sequence information and contains a range of features to enable everything from efficient review of everyday STR profiles to detailed analysis of the most challenging samples.
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    Illumina Connected Analytics
    Store, archive, manage, and collaborate on multi-omic datasets. Illumina Connected Analytics is a secure genomic data platform to operationalize informatics and drive scientific insights. Easily import, build, and edit workflows with tools like CWL and Nextflow. Leverage DRAGEN bioinformatics pipelines. Organize data in a secure workspace and share it globally in a compliant manner. Keep your data in your cloud environment while using our platform. Visualize and interpret your data with a flexible analysis environment, including JupyterLab Notebooks. Aggregate, query, and analyze sample and population data in a scalable data warehouse. Scale analysis operations by building, validating, automating, and deploying informatics pipelines. Reduce the time required to analyze genomic data, when swift results can be a critical factor. Enable comprehensive profiling to identify novel drug targets and drug response biomarkers. Flow data seamlessly from Illumina sequencing systems.
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    VSClinical

    VSClinical

    Golden Helix

    VSClinical allows for the clinical interpretation of variants based on ACMG & AMP guidelines. The VSClinical guided workflow enables following the American College of Medical Genetics (ACMG) guidelines used to identify and classify causal variants for inherited disease risk, cancer predisposition, and the diagnosis of rare diseases. The ACMG/AMP joint guidelines for variant interpretation provide a set of criteria to score variants and place them into one of five classification tiers. Following the guidelines requires deep diving into the annotations, genomic context, and existing clinical assertions about every variant. VSClinical provides a tailored workflow to score each relevant criterion while also providing all the bioinformatic, literature and evidence from clinical knowledgebases to assist in the scoring and interpretation process. VSClinical is designed to allow variant scientists to efficiently process variants.
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    BioTuring Browser

    BioTuring Browser

    BioTuring Browser

    Explore hundreds of curated single-cell transcriptome datasets, along with your own data, through interactive visualizations and analytics. The software also supports multimodal omics, CITE-seq, TCR-seq, and spatial transcriptomic. Interactively explore the world's largest single-cell expression database. Access and query insights from a single-cell database of millions of cells, fully annotated with cell type labels and experimental metadata. Not just creating a gateway to published works, BioTuring Browser is an end-to-end solution for your own single-cell data. Import your fastq files, count matrices, Seurat, or Scanpy objects, and reveal the biological stories inside them. Get a rich package of visualizations and analyses in an intuitive interface, making insight mining from any curated or in-house single-cell dataset become such a breeze. Import single-cell CRISPR screening or Perturb-seq data, and query guide RNA sequences.
    Starting Price: Free
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    OmicsBox

    OmicsBox

    BioBam Bioinformatics S.L.

    OmicsBox is a leading bioinformatics solution that offers end-to-end data analysis of genomes, transcriptomes, metagenomes, and genetic variation studies. The application is used by top private and public research institutions worldwide and allows researchers to easily process large and complex data sets, and streamline their analysis process. It is designed to be user-friendly, efficient, and with a powerful set of tools to extract biological insights from omics data. The software is structured in different modules, each with a specific set of tools and functions designed to perform different types of analysis, such as de-novo genome assemblies, genetic variation analysis, differential expression analysis, and taxonomic classifications of microbiome data, including the functional interpretation and rich visualizations of results. The functional analysis module includes the popular Blast2GO annotation methodology and makes OmicsBox particularly suited for non-model organism research
    Starting Price: €100/month/seat
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    SnapGene

    SnapGene

    SnapGene

    Accurately design and simulate cloning procedures. Test complicated projects, catch errors before they happen, and obtain the right constructs the first time. Cloning is easier when you can see what you are doing. The intuitive interface offers you unparalleled visibility into your work, simplifying often complex tasks. SnapGene automates documentation, so you don’t have to. See and share every sequence edit and cloning procedure that led to your final plasmid. Improve your core molecular biology procedures, and improve your results. Master SnapGene and key concepts in cloning with our new online learning center, SnapGene Academy. Containing over 50 video tutorials taught by scientific experts, SnapGene Academy helps you advance your skills across multiple molecular biology courses. SnapGene 7.2 provides a new visualization of primer homodimer structures and enhancements to file management, allowing tabs to be organized in multiple windows using drag and drop.
    Starting Price: $295 per year
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    Eidogen-Sertanty Target Informatics Platform (TIP)
    Eidogen-Sertanty's Target Informatics Platform (TIP) is the world's first structural informatics system and knowledgebase that enables researchers with the ability to interrogate the druggable genome from a structural perspective. TIP amplifies the rapidly expanding body of experimental protein structure information and transforms structure-based drug discovery from a low-throughput, data-scarce discipline into a high-throughput, data-rich science. Designed to help bridge the knowledge gap between bioinformatics and cheminformatics, TIP supplies drug discovery researchers with a knowledge base of information that is both distinct from and highly complementary to information furnished by existing bio- and cheminformatics platforms. TIP's seamless integration of structural data management technology with unique target-to-lead calculation and analysis capabilities enhances all stages of the discovery pipeline.
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    Prosol

    Prosol

    Coda Technology Solutions Pvt Ltd

    PROSOL by CODASOL is a revolutionary Master Data Management (MDM) platform designed to address the ongoing challenges of data quality decay experienced by large enterprises. Traditional annual data cleansing projects often provide only temporary solutions to data quality issues. Organizations frequently rely on consulting firms to standardize and improve master data quality, only to find that these improvements are short-lived, leading to recurring costs and inefficiencies. PROSOL integrates an "always-on" data quality assurance program directly into your master data management processes. This ensures that data quality is maintained continuously, reducing the need for periodic cleansing exercises and associated costs. Utilizing advanced deep learning algorithms such as Word2Vec, Long-Short Term Memory (LSTM), and Sequence-to-Sequence Models, PROSOL offers superior product specification matching and similarity measures.
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    Mirada XD

    Mirada XD

    Mirada Medical

    Comprehensive software for PET/CT, PET/MR, nuclear medicine and image fusion powered by world-class deformable registration and accurate quantification tools. With Mirada XD, you can load unlimited multi-time point follow-up studies for your review, multi-timepoint gated (4D) CT and PET data, as well as multi-sequence MR and multi-phase CT data. You can switch between MR sequences/gates in real-time even in a fused view. Performing efficient reading with unlimited SPECT and SPECT/CT studies, data from stand-alone NM SPECT scanner can be fused to diagnostic CT, eliminating the need for expensive SPECT/CT hardware. With Mirada XD you can perform an efficient reading with unlimited SPECT and SPECT/CT studies. Data from a stand-alone NM SPECT scanner can be fused to diagnostic CT eliminating the need for expensive SPECT/CT hardware.