Evo 2Arc Institute
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NVIDIA PhysicsNeMoNVIDIA
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About
Evo 2 is a genomic foundation model capable of generalist prediction and design tasks across DNA, RNA, and proteins. It utilizes a frontier deep learning architecture to model biological sequences at single-nucleotide resolution, achieving near-linear scaling of compute and memory relative to context length. Trained with 40 billion parameters and a 1 megabase context length, Evo 2 processes over 9 trillion nucleotides from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function prediction across multiple biological modalities, including DNA, RNA, and proteins, and to generate novel sequences with plausible genomic architecture. The model's capabilities have been demonstrated in tasks such as designing functional CRISPR systems and predicting disease-causing mutations in human genes. Evo 2 is publicly accessible via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework.
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About
NVIDIA PhysicsNeMo is an open source Python deep-learning framework for building, training, fine-tuning, and inferring physics-AI models that combine physics knowledge with data to accelerate simulations, create high-fidelity surrogate models, and enable near-real-time predictions across domains such as computational fluid dynamics, structural mechanics, electromagnetics, weather and climate, and digital twin applications. It provides scalable, GPU-accelerated tools and Python APIs built on PyTorch and released under the Apache 2.0 license, offering curated model architectures including physics-informed neural networks, neural operators, graph neural networks, and generative AI–based approaches so developers can harness physics-driven causality alongside observed data for engineering-grade modeling. PhysicsNeMo includes end-to-end training pipelines from geometry ingestion to differential equations, reference application recipes to jump-start workflows.
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Platforms Supported
Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook
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Platforms Supported
Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook
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Audience
Computational biologists and genetic engineers in need of a tool to model and design biological sequences across multiple modalities, enhancing research in genomics and synthetic biology
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Audience
Researchers, engineers, and developers who need an open source Python AI framework to build, train, fine-tune, and deploy physics-informed machine learning models for simulation, digital twins, and real-time prediction
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Support
Phone Support
24/7 Live Support
Online
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Support
Phone Support
24/7 Live Support
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API
Offers API
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API
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Pricing
No information available.
Free Version
Free Trial
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Pricing
Free
Free Version
Free Trial
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Reviews/
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Training
Documentation
Webinars
Live Online
In Person
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Training
Documentation
Webinars
Live Online
In Person
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Company InformationArc Institute
United States
arcinstitute.org/tools/evo
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Company InformationNVIDIA
Founded: 1993
United States
developer.nvidia.com/physicsnemo
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