ESMFold2

ESMFold2

Biohub
+
+

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About

ESMFold2 is the successor to ESMFold, setting a new state of the art for single-sequence structure prediction and enabling the generation of new functional proteins through searching the ESMC model’s latent space. The model predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequence, with optional multiple sequence alignment input for enhanced accuracy on challenging targets. It is designed for structure prediction using sequence and structure modalities, with ESM representations powering a series of looped folding layers and a diffusion model projecting pairwise representations to atomic-resolution predictions. ESMFold2 predicts protein structures directly from amino acid sequences and outputs comprehensive structural information, including all-atom coordinates for backbone and side chains, confidence metrics, and optional distogram predictions for detailed structural analysis.

About

NVIDIA® Parabricks® is the only GPU-accelerated suite of genomic analysis applications that delivers fast and accurate analysis of genomes and exomes for sequencing centers, clinical teams, genomics researchers, and high-throughput sequencing instrument developers. NVIDIA Parabricks provides GPU-accelerated versions of tools used every day by computational biologists and bioinformaticians—enabling significantly faster runtimes, workflow scalability, and lower compute costs. From FastQ to Variant Call Format (VCF), NVIDIA Parabricks accelerates runtimes across a series of hardware configurations with NVIDIA A100 Tensor Core GPUs. Genomic researchers can experience acceleration across every step of their analysis workflows, from alignment to sorting to variant calling. When more GPUs are used, a near-linear scaling in compute time is observed compared to CPU-only systems, allowing up to 107X acceleration.

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Audience

Structural biology researchers who need fast, high-resolution protein structure prediction from sequence for analysis, exploration, and experimental planning

Audience

Organizations looking for an AI-based tool for analysis of high-throughput DNA and RNA sequencing data

Support

Phone Support
24/7 Live Support
Online

Support

Phone Support
24/7 Live Support
Online

API

Offers API

API

Offers API

Screenshots and Videos

Screenshots and Videos

Pricing

Free
Free Version
Free Trial

Pricing

No information available.
Free Version
Free Trial

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

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Review this Software

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Training

Documentation
Webinars
Live Online
In Person

Training

Documentation
Webinars
Live Online
In Person

Company Information

Biohub
Founded: 2016
United States
biohub.ai/models/esmfold2

Company Information

NVIDIA
Founded: 1993
United States
www.nvidia.com/en-us/clara/genomics/

Alternatives

Alternatives

ESMC

ESMC

Biohub
Evo 2

Evo 2

Arc Institute
Evo 2

Evo 2

Arc Institute
VarSeq

VarSeq

Golden Helix
HyperProtein

HyperProtein

Hypercube

Categories

Categories

Integrations

Amazon Web Services (AWS)
Biohub
Google Cloud Platform
Microsoft Azure
Oracle Cloud Infrastructure
Python

Integrations

Amazon Web Services (AWS)
Biohub
Google Cloud Platform
Microsoft Azure
Oracle Cloud Infrastructure
Python
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