ESMFold2

ESMFold2

Biohub
Ideogram 4.0

Ideogram 4.0

Ideogram
+
+

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About

ESMFold2 is the successor to ESMFold, setting a new state of the art for single-sequence structure prediction and enabling the generation of new functional proteins through searching the ESMC model’s latent space. The model predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequence, with optional multiple sequence alignment input for enhanced accuracy on challenging targets. It is designed for structure prediction using sequence and structure modalities, with ESM representations powering a series of looped folding layers and a diffusion model projecting pairwise representations to atomic-resolution predictions. ESMFold2 predicts protein structures directly from amino acid sequences and outputs comprehensive structural information, including all-atom coordinates for backbone and side chains, confidence metrics, and optional distogram predictions for detailed structural analysis.

About

Ideogram 4.0 is an open image model at the forefront of design, built for open weights, multilingual text, precise layout control, editable elements, and realistic 2K images. It is a state-of-the-art open-weight image model for developers and enterprises that want to build, fine-tune, and run visual intelligence on their own hardware. Ideogram 4.0 was trained with a describe-to-structure-to-recreate loop, first reading scenes, backgrounds, text, and objects as structured data, then learning to rebuild images from that representation. This approach is designed to help the model understand composition before recreating it, giving teams more control over layout, objects, typography, and visual structure. It is built for real design work, especially brand, advertising, fashion, marketing, food, apparel, social, photography, and illustration use cases. Ideogram has led on text rendering since launch, and 4.0 adds bounding-box layout control so headlines stay readable.

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Audience

Structural biology researchers who need fast, high-resolution protein structure prediction from sequence for analysis, exploration, and experimental planning

Audience

Brand, product, and creative technology teams that need an image model for controlled design generation, readable text, brand-consistent visuals, and production-ready creative workflows

Support

Phone Support
24/7 Live Support
Online

Support

Phone Support
24/7 Live Support
Online

API

Offers API

API

Offers API

Screenshots and Videos

Screenshots and Videos

Pricing

Free
Free Version
Free Trial

Pricing

Free
Free Version
Free Trial

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Training

Documentation
Webinars
Live Online
In Person

Training

Documentation
Webinars
Live Online
In Person

Company Information

Biohub
Founded: 2016
United States
biohub.ai/models/esmfold2

Company Information

Ideogram
Founded: 2022
Canada
ideogram.ai/models/4.0/

Alternatives

Alternatives

Reve 2.0

Reve 2.0

Reve
ESMC

ESMC

Biohub
FLUX.2

FLUX.2

Black Forest Labs
Evo 2

Evo 2

Arc Institute
HyperProtein

HyperProtein

Hypercube

Categories

Categories

Integrations

Biohub
Collart
Ideogram AI
Model Context Protocol (MCP)
Python

Integrations

Biohub
Collart
Ideogram AI
Model Context Protocol (MCP)
Python
Claim ESMFold2 and update features and information
Claim ESMFold2 and update features and information
Claim Ideogram 4.0 and update features and information
Claim Ideogram 4.0 and update features and information