ESMFold2

ESMFold2

Biohub
+
+

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About

ESMFold2 is the successor to ESMFold, setting a new state of the art for single-sequence structure prediction and enabling the generation of new functional proteins through searching the ESMC model’s latent space. The model predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequence, with optional multiple sequence alignment input for enhanced accuracy on challenging targets. It is designed for structure prediction using sequence and structure modalities, with ESM representations powering a series of looped folding layers and a diffusion model projecting pairwise representations to atomic-resolution predictions. ESMFold2 predicts protein structures directly from amino acid sequences and outputs comprehensive structural information, including all-atom coordinates for backbone and side chains, confidence metrics, and optional distogram predictions for detailed structural analysis.

About

GPT-Rosalind is a purpose-built frontier reasoning model developed by OpenAI to accelerate scientific research across biology, drug discovery, and translational medicine. It is designed specifically for life sciences workflows, where researchers must navigate large volumes of literature, experimental data, and specialized databases to generate and validate new ideas. It combines deep domain understanding in areas such as chemistry, genomics, protein engineering, and disease biology with advanced tool-use capabilities, allowing it to interact with scientific databases, analyze experimental outputs, and support complex, multi-step reasoning tasks. It can assist with evidence synthesis, hypothesis generation, literature review, sequence interpretation, and experimental planning, helping scientists move faster from raw data to actionable insights. GPT-Rosalind transforms complex, time-intensive research processes into more efficient AI-assisted workflows.

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Audience

Structural biology researchers who need fast, high-resolution protein structure prediction from sequence for analysis, exploration, and experimental planning

Audience

Bioinformaticians, computational biologists, and pharmaceutical research teams who need AI to accelerate hypothesis generation, data analysis, and experimental design in life sciences

Support

Phone Support
24/7 Live Support
Online

Support

Phone Support
24/7 Live Support
Online

API

Offers API

API

Offers API

Screenshots and Videos

Screenshots and Videos

Pricing

Free
Free Version
Free Trial

Pricing

No information available.
Free Version
Free Trial

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

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Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Training

Documentation
Webinars
Live Online
In Person

Training

Documentation
Webinars
Live Online
In Person

Company Information

Biohub
Founded: 2016
United States
biohub.ai/models/esmfold2

Company Information

OpenAI
Founded: 2015
United States
openai.com/index/introducing-gpt-rosalind/

Alternatives

Alternatives

ESMC

ESMC

Biohub
Evo 2

Evo 2

Arc Institute
HyperProtein

HyperProtein

Hypercube

Categories

Categories

Integrations

Biohub
ChatGPT
Codex CLI
OpenAI
Python

Integrations

Biohub
ChatGPT
Codex CLI
OpenAI
Python
Claim ESMFold2 and update features and information
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