ESMC

ESMC

Biohub
SILCS

SILCS

SilcsBio
ESMC SILCS

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ESMC:

About

ESMC is the latest in the ESM family of protein language models, establishing a new frontier in representation learning for protein biology. Trained on billions of evolutionary sequences, it learns representations that reflect a mechanistic reduction of protein structure and function. The model is built on a transformer architecture, supports sequences as its core modality, and is trained on up to 6 billion proteins. ESMC is designed for protein science research, including structure prediction, function annotation, protein design, and understanding evolutionary relationships between proteins. It can generate novel proteins from partial sequence, structure, or functional constraints, helping researchers explore new possibilities in protein design and biological discovery. The Biohub Platform provides access to ESMC through the API and the ESM Python package, with quickstart resources for installing the package, creating an API key, connecting to the platform.
SILCS:

About

Site-Identification by Ligand Competitive Saturation (SILCS) generates 3D maps (FragMaps) of interaction patterns for chemical functional groups with your target molecule. Site-Identification by Ligand Competitive Saturation (SILCS) generates 3D maps (FragMaps) of interaction patterns for chemical functional groups with your target molecule. SILCS reveals intricacies of dynamics and provides tools to optimize ligand scaffolds using qualitative and quantitative binding pockets insights allowing more rapid and effective drug design. SILCS uses multiple small molecule probes with various functional groups, explicit solvent modeling, and target molecule flexibility to perform protein target mapping. Visualize favorable interactions with the target macromolecule. Gain insights to design better ligands with optimally placed functional groups.
ESMC:

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported
SILCS:

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported
ESMC:

Audience

Protein science researchers who need transformer-based sequence representations for structure prediction, function annotation, mutation analysis, and protein design
SILCS:

Audience

Laboratories searching for a dynamic molecule design software to create end-to-end drug design workflows
ESMC:

Support

Phone Support Not Supported
24/7 Live Support Not Supported
Online Supported
SILCS:

Support

Phone Support Supported
24/7 Live Support Not Supported
Online Supported
ESMC:

API

Offers API Supported
SILCS:

API

Offers API Not Supported
ESMC:

Screenshots and Videos

SILCS:

Screenshots and Videos

ESMC:

Pricing

Free
Free Version Supported
Free Trial Not Supported
SILCS:

Pricing

No information available.
Free Version Not Supported
Free Trial Not Supported
ESMC:

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

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Review this Software
SILCS:

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software
ESMC:

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Not Supported
SILCS:

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Not Supported
ESMC:

Company Information

Biohub
Founded: 2016
United States
biohub.ai/models/esmc
SILCS:

Company Information

SilcsBio
Founded: 2012
United States
silcsbio.com/software/
ESMC:

Alternatives

SILCS:

Alternatives

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SILCS:
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ESMC:
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ESMFold2

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SILCS:
ESMC:
SILCS:
LigPlot+

LigPlot+

EMBL-EBI
ESMC:
HyperProtein

HyperProtein

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SILCS:
ESMC:

Categories

AI Models Supported
AI Science Supported
SILCS:

Categories

Drug Discovery Supported
ESMC:

Integrations

Biohub Supported
Python Supported
SILCS:

Integrations

Biohub Not Supported
Python Not Supported
ESMC:
Claim ESMC and update features and information
Claim ESMC and update features and information
SILCS:
Claim SILCS and update features and information
Claim SILCS and update features and information