ESMC

ESMC

Biohub
LigPlot+

LigPlot+

EMBL-EBI
ESMC LigPlot+

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ESMC:

About

ESMC is the latest in the ESM family of protein language models, establishing a new frontier in representation learning for protein biology. Trained on billions of evolutionary sequences, it learns representations that reflect a mechanistic reduction of protein structure and function. The model is built on a transformer architecture, supports sequences as its core modality, and is trained on up to 6 billion proteins. ESMC is designed for protein science research, including structure prediction, function annotation, protein design, and understanding evolutionary relationships between proteins. It can generate novel proteins from partial sequence, structure, or functional constraints, helping researchers explore new possibilities in protein design and biological discovery. The Biohub Platform provides access to ESMC through the API and the ESM Python package, with quickstart resources for installing the package, creating an API key, connecting to the platform.
LigPlot+:

About

LigPlot+ is a successor to our original LIGPLOT program for the automatic generation of 2D ligand-protein interaction diagrams. It is run from an intuitive java interface that allows on-screen editing of the plots via mouse click-and-drag operations. In addition to the new interface, the program includes several major enhancements over the old version. When two or more ligand-protein complexes are sufficiently similar, LigPlot+ can automatically display their interaction diagrams either superposed or side by side. Any conserved interactions are highlighted. The LigPlot+ suite also now includes an update of the original DIMPLOT program for plotting protein-protein or domain-domain interactions. Users can flexibly select the interface of interest and DIMPLOT will then generate a diagram showing the residue-residue interactions across the interface. To assist in interpretation, the residues in one of the interfaces can be optionally displayed in sequence order.
ESMC:

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported
LigPlot+:

Platforms Supported

Windows Supported
Mac Supported
Linux Supported
Cloud Not Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported
ESMC:

Audience

Protein science researchers who need transformer-based sequence representations for structure prediction, function annotation, mutation analysis, and protein design
LigPlot+:

Audience

Labs and researchers interested in a solution to create and visualize ligand-protein interaction diagrams
ESMC:

Support

Phone Support Not Supported
24/7 Live Support Not Supported
Online Supported
LigPlot+:

Support

Phone Support Supported
24/7 Live Support Not Supported
Online Supported
ESMC:

API

Offers API Supported
LigPlot+:

API

Offers API Not Supported
ESMC:

Screenshots and Videos

LigPlot+:

Screenshots and Videos

ESMC:

Pricing

Free
Free Version Supported
Free Trial Not Supported
LigPlot+:

Pricing

No information available.
Free Version Not Supported
Free Trial Not Supported
ESMC:

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software
LigPlot+:

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software
ESMC:

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Not Supported
LigPlot+:

Training

Documentation Supported
Webinars Supported
Live Online Not Supported
In Person Supported
ESMC:

Company Information

Biohub
Founded: 2016
United States
biohub.ai/models/esmc
LigPlot+:

Company Information

EMBL-EBI
United Kingdom
www.ebi.ac.uk/thornton-srv/software/LigPlus/
ESMC:

Alternatives

LigPlot+:

Alternatives

SILCS

SILCS

SilcsBio
ESMC:
Evo 2

Evo 2

Arc Institute
LigPlot+:
3decision

3decision

Discngine
ESMC:
ESMFold2

ESMFold2

Biohub
LigPlot+:
Aurora Drug Discovery

Aurora Drug Discovery

Aurora Fine Chemicals
ESMC:
LigPlot+:
ESMC:
HyperProtein

HyperProtein

Hypercube
LigPlot+:
ESMC:

Categories

AI Models Supported
AI Science Supported
LigPlot+:

Categories

Drug Discovery Supported
ESMC:

Integrations

Biohub Supported
Python Supported
LigPlot+:

Integrations

Biohub Not Supported
Python Not Supported
ESMC:
Claim ESMC and update features and information
Claim ESMC and update features and information
LigPlot+:
Claim LigPlot+ and update features and information
Claim LigPlot+ and update features and information