ESMFold2Biohub
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Related Products
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About
Differential Bio is a virtual scale-up platform for bioprocess optimization that makes microbial growth more predictable, scalable, and cost-effective through robotic lab automation and AI-driven insights. Its workflow begins with automated, high-throughput experiments that mimic large-scale stress factors in microliter environments and generate industry-relevant wet-lab data through liquid handling, fermentation, and measurement. Specialized AI models use that data to predict outcomes such as biomass growth, protein expression, cell viability, titer, production rate, yield, and cost. Through the web-based platform, teams can configure optimization goals and parameter ranges, run unlimited in-silico experiments, compare simulated fermentation outcomes, perform multi-objective optimization, and identify process conditions to implement at scale.
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About
ESMFold2 is the successor to ESMFold, setting a new state of the art for single-sequence structure prediction and enabling the generation of new functional proteins through searching the ESMC model’s latent space. The model predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequence, with optional multiple sequence alignment input for enhanced accuracy on challenging targets. It is designed for structure prediction using sequence and structure modalities, with ESM representations powering a series of looped folding layers and a diffusion model projecting pairwise representations to atomic-resolution predictions. ESMFold2 predicts protein structures directly from amino acid sequences and outputs comprehensive structural information, including all-atom coordinates for backbone and side chains, confidence metrics, and optional distogram predictions for detailed structural analysis.
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Platforms Supported
Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook
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Platforms Supported
Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook
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Audience
Precision-fermentation process scientists who need to optimize microbial production and reduce uncertainty before industrial scale-up
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Audience
Structural biology researchers who need fast, high-resolution protein structure prediction from sequence for analysis, exploration, and experimental planning
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Support
Phone Support
24/7 Live Support
Online
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Support
Phone Support
24/7 Live Support
Online
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API
Offers API
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API
Offers API
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Screenshots and Videos |
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Pricing
No information available.
Free Version
Free Trial
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Pricing
Free
Free Version
Free Trial
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Reviews/
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Reviews/
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Training
Documentation
Webinars
Live Online
In Person
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Training
Documentation
Webinars
Live Online
In Person
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Company InformationDifferential Bio
Germany
www.differential.bio/
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Company InformationBiohub
Founded: 2016
United States
biohub.ai/models/esmfold2
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Categories |
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Integrations
Biohub
Python
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