ESMC

ESMC

Biohub
+
+

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About

Claude Mythos 5.1 is Anthropic’s newest Mythos-class model, designed for advanced cybersecurity, biology, scientific research, coding, and long-running knowledge work. It is the same underlying model as Claude Fable 5.1 but uses different safeguards: Fable 5.1 is generally available, while Mythos 5.1 is restricted to trusted access programs with safeguards specifically designed for cybersecurity and life sciences research. The model sets a new performance frontier for agentic coding and demonstrates the strongest cyber capabilities of any Anthropic model released to date. In scientific research, Mythos 5.1 can work with specialized tools and complex workflows across molecular design, computational biology, and other technical domains. In Anthropic’s experiments, it designed high-affinity protein binders across multiple targets and achieved its strongest measured hit rate to date. It also optimized seven open-source protein and genomics deep learning models.

About

ESMC is the latest in the ESM family of protein language models, establishing a new frontier in representation learning for protein biology. Trained on billions of evolutionary sequences, it learns representations that reflect a mechanistic reduction of protein structure and function. The model is built on a transformer architecture, supports sequences as its core modality, and is trained on up to 6 billion proteins. ESMC is designed for protein science research, including structure prediction, function annotation, protein design, and understanding evolutionary relationships between proteins. It can generate novel proteins from partial sequence, structure, or functional constraints, helping researchers explore new possibilities in protein design and biological discovery. The Biohub Platform provides access to ESMC through the API and the ESM Python package, with quickstart resources for installing the package, creating an API key, connecting to the platform.

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Audience

Cybersecurity, life sciences, and research organizations needing frontier AI capabilities for advanced coding, scientific discovery, biological research, and long-running technical work

Audience

Protein science researchers who need transformer-based sequence representations for structure prediction, function annotation, mutation analysis, and protein design

Support

Phone Support
24/7 Live Support
Online

Support

Phone Support
24/7 Live Support
Online

API

Offers API

API

Offers API

Screenshots and Videos

Screenshots and Videos

Pricing

No information available.
Free Version
Free Trial

Pricing

Free
Free Version
Free Trial

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

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Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Training

Documentation
Webinars
Live Online
In Person

Training

Documentation
Webinars
Live Online
In Person

Company Information

Anthropic
Founded: 2021
United States
claude.ai

Company Information

Biohub
Founded: 2016
United States
biohub.ai/models/esmc

Alternatives

Alternatives

GPT-5.6 Sol

GPT-5.6 Sol

OpenAI
Evo 2

Evo 2

Arc Institute
GPT-6 Astra

GPT-6 Astra

OpenAI
ESMFold2

ESMFold2

Biohub
Claude Mythos 5

Claude Mythos 5

Anthropic
Claude Fable 5

Claude Fable 5

Anthropic
HyperProtein

HyperProtein

Hypercube

Categories

Categories

Integrations

Python
Augment Code
Biela.dev
Bolt.new
C
C#
Claude Science
Dart
Dessix
Doraverse
Emergent
GoLand
Microsoft Foundry
Muse
PowerShell
Ruby
RustRover
Solidity
Thread Deck
Yonoo

Integrations

Python
Augment Code
Biela.dev
Bolt.new
C
C#
Claude Science
Dart
Dessix
Doraverse
Emergent
GoLand
Microsoft Foundry
Muse
PowerShell
Ruby
RustRover
Solidity
Thread Deck
Yonoo
Claim Claude Mythos 5.1 and update features and information
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