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About

Biohub is an open platform for building on the world model of protein biology. It provides access to the ESM family of models, including ESMC, ESMFold2, and ESM3, along with interactive tools and developer resources for protein science research. ESMC is a state-of-the-art protein language model trained on billions of evolutionary sequences, building representations that capture fundamental mechanisms of protein structure and function. It powers functional analysis, structure prediction, protein design, and the exploration of evolutionary relationships between proteins. ESMFold2 predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequence, with optional multiple sequence alignment input for enhanced accuracy on challenging targets. ESM3 jointly models sequence, structure, and function, enabling controllable generation of novel proteins by conditioning on any combination of these modalities.

About

Goodfire helps teams understand and debug AI models by uncovering the hidden representations inside neural networks and removing the guesswork from AI training, moving model development from alchemy to precision engineering. Its platform, Silico, is built for intentional model design, letting teams build AI models with the precision of written software by seeing what models have learned, finding undesired behavior, and making targeted interventions to improve performance. Goodfire’s methods reverse engineer the causal mechanisms of AI to reveal internal structure, uncover novel science, and validate when predictions reflect true understanding. It helps teams precisely debug model behavior, identify and remove confounders, diagnose failures before they occur in production, and control training so the model learns what is intended with less data and fewer off-target effects. It works across different types of AI models, including life sciences models, robotics, and vision models.

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported

Audience

Computational biologists and protein engineering teams that need AI models, structure prediction tools, and protein-scale datasets for discovery and design

Audience

AI research, ML engineering, and applied science teams that need to interpret, debug, and precisely improve advanced neural networks

Support

Phone Support Not Supported
24/7 Live Support Not Supported
Online Supported

Support

Phone Support Not Supported
24/7 Live Support Not Supported
Online Supported

API

Offers API Supported

API

Offers API Not Supported

Screenshots and Videos

Screenshots and Videos

Pricing

No information available.
Free Version Not Supported
Free Trial Not Supported

Pricing

No information available.
Free Version Not Supported
Free Trial Not Supported

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

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Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Training

Documentation Supported
Webinars Not Supported
Live Online Supported
In Person Not Supported

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Not Supported

Company Information

Biohub
Founded: 2016
United States
biohub.ai/

Company Information

Goodfire AI
Founded: 2024
United States
www.goodfire.ai/

Alternatives

ESMC

ESMC

Biohub

Alternatives

ESMFold2

ESMFold2

Biohub
HyperProtein

HyperProtein

Hypercube
Evo 2

Evo 2

Arc Institute

Categories

AI Science Supported
Bioinformatics Supported

Categories

AI Development Supported

Integrations

ESMC Supported
ESMFold2 Supported

Integrations

ESMC Not Supported
ESMFold2 Not Supported
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Claim Biohub and update features and information
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