NeedlemanWunsch

MOVED TO GITHUB: https://github.com/noporpoise/seq-align

Global optimal sequence alignment using the Needleman-Wunsch algorithm.

Aligns DNA, RNA, protein sequence and more!

See our sister project local alignment using Smith-Waterman:
http://sourceforge.net/projects/smithwaterman/

Features

Affine gap penalties
Can set no gap penalty for gaps at the beginning and end of alignments
Coloured ouput
Reads FASTA, FASTQ and plain sequence files (inc. gzip'ed files)
Preset DNA/Protein substitution matrices (PAM/BLOSUM etc)
Can load substitution penalty matrices
Portable C code that can be used in other bioinformatics projects

Project Samples

Project Activity

See All Activity >

License

GNU General Public License version 3.0 (GPLv3)

Follow NeedlemanWunsch

NeedlemanWunsch Web Site

Other Useful Business Software

Build Agents and Models on One Platform

Everything you need to build production-ready agents and models. Access 200+ Google and third-party AI models and tools.

Gemini Enterprise Agent Platform is Google Cloud's comprehensive platform for developers to build, scale, govern, and optimize agents and models. Choose from Google's most advanced models and third-party models like Anthropic's Claude Model Family.

Try It Free

Rate This Project

User Reviews

Be the first to post a review of NeedlemanWunsch!

Additional Project Details

Operating Systems

BSD, Linux, Mac

Intended Audience

Education, Science/Research

User Interface

Command-line, Console/Terminal

Programming Language

C, C++

Related Categories

C++ Bio-Informatics Software, C Bio-Informatics Software

Registered

2011-11-08

Similar Business Software

MEGA

MEGA (Molecular Evolutionary Genetics Analysis) is a powerful and user-friendly software suite designed for analyzing DNA and protein sequence data from species and populations. It facilitates both automatic and manual sequence alignment, phylogenetic tree inference, and evolutionary hypothesis...

See Software
OmnibusX

In the world of biological data science, navigating vast and complex datasets can be a daunting task. Our software toolkit is designed to empower you by accelerating analysis, promoting accessibility, and providing comprehensive visualization tools to help you make sense of these intricate...

See Software
Evo 2

Evo 2 is a genomic foundation model capable of generalist prediction and design tasks across DNA, RNA, and proteins. It utilizes a frontier deep learning architecture to model biological sequences at single-nucleotide resolution, achieving near-linear scaling of compute and memory relative to...

See Software
Geneious

Geneious Prime makes bioinformatics accessible by transforming raw data into visualizations that make sequence analysis intuitive and user-friendly. Simple sequence assembly and easy editing of contigs. Automatic annotation for gene prediction, motifs, translation, and variant calling. Genotype...

See Software
Genome Analysis Toolkit (GATK)

Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. The GATK...

See Software
Biohub

Biohub is an open platform for building on the world model of protein biology. It provides access to the ESM family of models, including ESMC, ESMFold2, and ESM3, along with interactive tools and developer resources for protein science research. ESMC is a state-of-the-art protein language model...

See Software