[sbml-svn] SF.net SVN: sbml:[21758] trunk/specifications/sbml-level-3/version-1/fbc/ spec

[<bg...@us...>]

Revision: 21758
          http://sourceforge.net/p/sbml/code/21758
Author:   bgoli
Date:     2014-11-25 22:56:06 +0000 (Tue, 25 Nov 2014)
Log Message:
-----------
FBC Version 2 RC1 text - gene associations - integrated into existing FBC specification.

Modified Paths:
--------------
    trunk/specifications/sbml-level-3/version-1/fbc/spec/background.tex
    trunk/specifications/sbml-level-3/version-1/fbc/spec/main.pdf
    trunk/specifications/sbml-level-3/version-1/fbc/spec/main.synctex
    trunk/specifications/sbml-level-3/version-1/fbc/spec/main.tex
    trunk/specifications/sbml-level-3/version-1/fbc/spec/syntax.tex

Added Paths:
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    trunk/specifications/sbml-level-3/version-1/fbc/spec/images/fbc_uml_v2.pdf
    trunk/specifications/sbml-level-3/version-1/fbc/spec/syntax_gene_association.tex

Modified: trunk/specifications/sbml-level-3/version-1/fbc/spec/background.tex
===================================================================
--- trunk/specifications/sbml-level-3/version-1/fbc/spec/background.tex	2014-11-25 22:50:30 UTC (rev 21757)
+++ trunk/specifications/sbml-level-3/version-1/fbc/spec/background.tex	2014-11-25 22:56:06 UTC (rev 21758)
@@ -17,10 +17,13 @@
 parameter ID's. Furthermore, reaction annotations are generally stored as
 tool specific HTML key-value pairs in a \Notes element which has routinely
 led to different research groups and software using in-house and/or tool
-specific ways to describe the same information. While a step in the right
-direction this format is not suitable for implementation in SBML~Level~3.
+specific ways to describe the same information. 
+%
+\newtxt{An common example of such an annotation is the so called `gene association' used to assess the effect of gene deletions on a reaction network.}
+%
+While a step in the right direction this format is not suitable for implementation in SBML~Level~3.
 
-It is worth noting that while SBML~Level~2 does have a construct know as
+It is worth noting that while SBML~Level~2 does have a construct known as
 \Constraint its function is limited to measuring and reporting the model
 variables behavior in time. In contrast the \FluxBound enforces the bounds
 on a steady-state flux and they can therefore be considered to be
@@ -35,17 +38,6 @@
 removed from SBML. This has had the effect that a significant number of
 tools and models are still limited to using SBML Level~2 Version~1.\cite{oberhardt_2009}
 
-\subsection{New in version 2}
-\label{intro-ga}
-Genome scale reconstructions (GSR) are widely used for biotechnological purposes for example creating or increasing the yield of a specific product, rerouting metabolic pathways and increasing biomass yield on specific substrates. In order to facilitate this GSR's are currently annotated with gene-protein relationships which relate particular metabolic genes (implicitly their product) with a protein (typically a protein, enzyme or transporter) that carries a specific metabolic flux. Using this knowledge it it is e.g.~possible to perform `in silico' gene knockout experiments or otherwise relate particular fluxes to measured gene expression levels.
-
-There is currently no standard way of encoding gene-protein relationships (GPR's) in an unambiguous and interoperable way. Currently, this information is encoded using free form annotations (typically stored as \Notes on the \Reaction element in SBML encoded GSR models).
-%
-\exampleFile{examples/ex_ga_bigg.txt}
-% <p>GENE_ASSOCIATION: CAC1001|CAC1369|CAC1819|CAC2832|CAC3031</p> doesn't encode properly with Mike's stylesheet but a classic nonetheless.
-
-Each of these GPR annotations was taken from a different SBML encoded model and uses a slightly different syntax either in the `key' or the `value' (bracketing, syntax, attribute definition, etc.). Note that these expressions contain either one or more than one identifier related in a logical expression. In version two of this specification we introduce a standardized format for encoding gene protein association in genome-scale, flux balance models.
-
 \subsection{Past work on this problem or similar topics}
 The problem of describing and annotating FBA models in SBML has been raised
 at various times in the past few years. In this regard there are two known

Added: trunk/specifications/sbml-level-3/version-1/fbc/spec/images/fbc_uml_v2.pdf
===================================================================
--- trunk/specifications/sbml-level-3/version-1/fbc/spec/images/fbc_uml_v2.pdf	                        (rev 0)
+++ trunk/specifications/sbml-level-3/version-1/fbc/spec/images/fbc_uml_v2.pdf	2014-11-25 22:56:06 UTC (rev 21758)
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+               </rdf:li>
+            </rdf:Alt>
+         </xmp:Thumbnails>
+      </rdf:Description>
+      <rdf:Description rdf:about=""
+            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/"
+            xmlns:stRef="http://ns.adobe.com/xap/1.0/sType/ResourceRef#"
+            xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#">
+         <xmpMM:InstanceID>uuid:7d7ec120-29db-4311-8a96-1b7fceb8246b</xmpMM:InstanceID>
+         <xmpMM:DocumentID>xmp.did:84DB4C85EF74E411A685EBB04370A41B</xmpMM:DocumentID>
+         <xmpMM:OriginalDocumentID>uuid:5D20892493BFDB11914A8590D31508C8</xmpMM:OriginalDocumentID>
+         <xmpMM:RenditionClass>proof:pdf</xmpMM:RenditionClass>
+         <xmpMM:DerivedFrom rdf:parseType="Resource">
+            <stRef:instanceID>uuid:a751a568-254b-4ff3-a51e-5e9b4b58bfed</stRef:instanceID>
+            <stRef:documentID>xmp.did:5675A1439C2DE21181F890CDC374FFF6</stRef:documentID>
+            <stRef:originalDocumentID>uuid:5D20892493BFDB11914A8590D31508C8</stRef:originalDocumentID>
+            <stRef:renditionClass>proof:pdf</stRef:renditionClass>
+         </xmpMM:DerivedFrom>
+         <xmpMM:History>
+            <rdf:Seq>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>converted</stEvt:action>
+                  <stEvt:params>from application/pdf to &lt;unknown&gt;</stEvt:params>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:D27F11740720681191099C3B601C4548</stEvt:instanceID>
+                  <stEvt:when>2008-04-17T14:19:15+05:30</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>converted</stEvt:action>
+                  <stEvt:params>from application/pdf to &lt;unknown&gt;</stEvt:params>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>converted</stEvt:action>
+                  <stEvt:params>from application/pdf to &lt;unknown&gt;</stEvt:params>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:F97F1174072068118D4ED246B3ADB1C6</stEvt:instanceID>
+                  <stEvt:when>2008-05-15T16:23:06-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:FA7F1174072068118D4ED246B3ADB1C6</stEvt:instanceID>
+                  <stEvt:when>2008-05-15T17:10:45-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:EF7F117407206811A46CA4519D24356B</stEvt:instanceID>
+                  <stEvt:when>2008-05-15T22:53:33-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:F07F117407206811A46CA4519D24356B</stEvt:instanceID>
+                  <stEvt:when>2008-05-15T23:07:07-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:F77F117407206811BDDDFD38D0CF24DD</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T10:35:43-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>converted</stEvt:action>
+                  <stEvt:params>from application/pdf to &lt;unknown&gt;</stEvt:params>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:F97F117407206811BDDDFD38D0CF24DD</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T10:40:59-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>converted</stEvt:action>
+                  <stEvt:params>from application/vnd.adobe.illustrator to &lt;unknown&gt;</stEvt:params>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:FA7F117407206811BDDDFD38D0CF24DD</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T11:26:55-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:FB7F117407206811BDDDFD38D0CF24DD</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T11:29:01-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:FC7F117407206811BDDDFD38D0CF24DD</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T11:29:20-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:FD7F117407206811BDDDFD38D0CF24DD</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T11:30:54-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:FE7F117407206811BDDDFD38D0CF24DD</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T11:31:22-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:B233668C16206811BDDDFD38D0CF24DD</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T12:23:46-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:B333668C16206811BDDDFD38D0CF24DD</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T13:27:54-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:B433668C16206811BDDDFD38D0CF24DD</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T13:46:13-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:F77F11740720681197C1BF14D1759E83</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T15:47:57-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:F87F11740720681197C1BF14D1759E83</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T15:51:06-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:F97F11740720681197C1BF14D1759E83</stEvt:instanceID>
+                  <stEvt:when>2008-05-16T15:52:22-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>converted</stEvt:action>
+                  <stEvt:params>from application/vnd.adobe.illustrator to application/vnd.adobe.illustrator</stEvt:params>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:FA7F117407206811B628E3BF27C8C41B</stEvt:instanceID>
+                  <stEvt:when>2008-05-22T13:28:01-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>converted</stEvt:action>
+                  <stEvt:params>from application/vnd.adobe.illustrator to application/vnd.adobe.illustrator</stEvt:params>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:FF7F117407206811B628E3BF27C8C41B</stEvt:instanceID>
+                  <stEvt:when>2008-05-22T16:23:53-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>converted</stEvt:action>
+                  <stEvt:params>from application/vnd.adobe.illustrator to application/vnd.adobe.illustrator</stEvt:params>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:07C3BD25102DDD1181B594070CEB88D9</stEvt:instanceID>
+                  <stEvt:when>2008-05-28T16:45:26-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>converted</stEvt:action>
+                  <stEvt:params>from application/vnd.adobe.illustrator to application/vnd.adobe.illustrator</stEvt:params>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:F87F1174072068119098B097FDA39BEF</stEvt:instanceID>
+                  <stEvt:when>2008-06-02T13:25:25-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:F77F117407206811BB1DBF8F242B6F84</stEvt:instanceID>
+                  <stEvt:when>2008-06-09T14:58:36-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:F97F117407206811ACAFB8DA80854E76</stEvt:instanceID>
+                  <stEvt:when>2008-06-11T14:31:27-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:0180117407206811834383CD3A8D2303</stEvt:instanceID>
+                  <stEvt:when>2008-06-11T22:37:35-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:01E540664A3DDD11BD33D3EB8D3A1068</stEvt:instanceID>
+                  <stEvt:when>2008-06-18T22:24:01+07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:6B6AE2A5723EDD11A6F1BABF7C5A7A51</stEvt:instanceID>
+                  <stEvt:when>2008-06-19T20:30:34-07:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>
+                     <rdf:Bag>
+                        <rdf:li>/</rdf:li>
+                     </rdf:Bag>
+                  </stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:5CC0AFC7C4D4E1118A8CBEA7F2E30EBA</stEvt:instanceID>
+                  <stEvt:when>2012-07-23T14:49:02+02:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS4</stEvt:softwareAgent>
+                  <stEvt:changed>/</stEvt:changed>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stEvt:action>saved</stEvt:action>
+                  <stEvt:instanceID>xmp.iid:84DB4C85EF74E411A685EBB04370A41B</stEvt:instanceID>
+                  <stEvt:when>2014-11-25T23:43:04+01:00</stEvt:when>
+                  <stEvt:softwareAgent>Adobe Illustrator CS6 (Windows)</stEvt:softwareAgent>
+                  <stEvt:changed>/</stEvt:changed>
+               </rdf:li>
+            </rdf:Seq>
+         </xmpMM:History>
+      </rdf:Description>
+      <rdf:Description rdf:about=""
+            xmlns:illustrator="http://ns.adobe.com/illustrator/1.0/">
+         <illustrator:StartupProfile>Print</illustrator:StartupProfile>
+      </rdf:Description>
+      <rdf:Description rdf:about=""
+            xmlns:xmpTPg="http://ns.adobe.com/xap/1.0/t/pg/"
+            xmlns:stDim="http://ns.adobe.com/xap/1.0/sType/Dimensions#"
+            xmlns:stFnt="http://ns.adobe.com/xap/1.0/sType/Font#"
+            xmlns:xmpG="http://ns.adobe.com/xap/1.0/g/">
+         <xmpTPg:HasVisibleOverprint>False</xmpTPg:HasVisibleOverprint>
+         <xmpTPg:HasVisibleTransparency>False</xmpTPg:HasVisibleTransparency>
+         <xmpTPg:NPages>1</xmpTPg:NPages>
+         <xmpTPg:MaxPageSize rdf:parseType="Resource">
+            <stDim:w>209.040815</stDim:w>
+            <stDim:h>253.176967</stDim:h>
+            <stDim:unit>Millimeters</stDim:unit>
+         </xmpTPg:MaxPageSize>
+         <xmpTPg:Fonts>
+            <rdf:Bag>
+               <rdf:li rdf:parseType="Resource">
+                  <stFnt:fontName>ArialMT</stFnt:fontName>
+                  <stFnt:fontFamily>Arial</stFnt:fontFamily>
+                  <stFnt:fontFace>Regular</stFnt:fontFace>
+                  <stFnt:fontType>Open Type</stFnt:fontType>
+                  <stFnt:versionString>Version 6.87</stFnt:versionString>
+                  <stFnt:composite>False</stFnt:composite>
+                  <stFnt:fontFileName>arial.ttf</stFnt:fontFileName>
+               </rdf:li>
+               <rdf:li rdf:parseType="Resource">
+                  <stFnt:fontName>Arial-BoldMT</stFnt:fontName>
+                  <stFnt:fontFamily>Arial</stFnt:fontFamily>
+                  <stFnt:fontFace>Bold</stFnt:fontFace>
+                  <stFnt:fontType>Open Type</stFnt:fontType>
+                  <stFnt:versionString>Version 6.87</stFnt:versionString>
+                  <stFnt:composite>False</stFnt:composite>
+                  <stFnt:fontFileName>arialbd.ttf</stFnt:fontFileName>
+               </rdf:li>
+            </rdf:Bag>
+         </xmpTPg:Fonts>
+         <xmpTPg:PlateNames>
+            <rdf:Seq>
+               <rdf:li>Cyan</rdf:li>
+               <rdf:li>Magenta</rdf:li>
+               <rdf:li>Yellow</rdf:li>
+               <rdf:li>Black</rdf:li>
+            </rdf:Seq>
+         </xmpTPg:PlateNames>
+         <xmpTPg:SwatchGroups>
+            <rdf:Seq>
+               <rdf:li rdf:parseType="Resource">
+                  <xmpG:groupName>Default Swatch Group</xmpG:groupName>
+                  <xmpG:groupType>0</xmpG:groupType>
+                  <xmpG:Colorants>
+                     <rdf:Seq>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>White</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>0.000000</xmpG:cyan>
+                           <xmpG:magenta>0.000000</xmpG:magenta>
+                           <xmpG:yellow>0.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>CMYK Red</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>0.000000</xmpG:cyan>
+                           <xmpG:magenta>100.000000</xmpG:magenta>
+                           <xmpG:yellow>100.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>CMYK Yellow</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>0.000000</xmpG:cyan>
+                           <xmpG:magenta>0.000000</xmpG:magenta>
+                           <xmpG:yellow>100.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>CMYK Green</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>100.000000</xmpG:cyan>
+                           <xmpG:magenta>0.000000</xmpG:magenta>
+                           <xmpG:yellow>100.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>CMYK Cyan</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>100.000000</xmpG:cyan>
+                           <xmpG:magenta>0.000000</xmpG:magenta>
+                           <xmpG:yellow>0.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>CMYK Blue</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>100.000000</xmpG:cyan>
+                           <xmpG:magenta>100.000000</xmpG:magenta>
+                           <xmpG:yellow>0.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>CMYK Magenta</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>0.000000</xmpG:cyan>
+                           <xmpG:magenta>100.000000</xmpG:magenta>
+                           <xmpG:yellow>0.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>C=15 M=100 Y=90 K=10</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>14.999998</xmpG:cyan>
+                           <xmpG:magenta>100.000000</xmpG:magenta>
+                           <xmpG:yellow>90.000000</xmpG:yellow>
+                           <xmpG:black>10.000002</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>C=0 M=90 Y=85 K=0</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>0.000000</xmpG:cyan>
+                           <xmpG:magenta>90.000000</xmpG:magenta>
+                           <xmpG:yellow>85.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>C=0 M=80 Y=95 K=0</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>0.000000</xmpG:cyan>
+                           <xmpG:magenta>80.000000</xmpG:magenta>
+                           <xmpG:yellow>95.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>C=0 M=50 Y=100 K=0</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>0.000000</xmpG:cyan>
+                           <xmpG:magenta>50.000000</xmpG:magenta>
+                           <xmpG:yellow>100.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>C=0 M=35 Y=85 K=0</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>0.000000</xmpG:cyan>
+                           <xmpG:magenta>35.000004</xmpG:magenta>
+                           <xmpG:yellow>85.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>C=5 M=0 Y=90 K=0</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>5.000001</xmpG:cyan>
+                           <xmpG:magenta>0.000000</xmpG:magenta>
+                           <xmpG:yellow>90.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>C=20 M=0 Y=100 K=0</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>19.999998</xmpG:cyan>
+                           <xmpG:magenta>0.000000</xmpG:magenta>
+                           <xmpG:yellow>100.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>C=50 M=0 Y=100 K=0</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>50.000000</xmpG:cyan>
+                           <xmpG:magenta>0.000000</xmpG:magenta>
+                           <xmpG:yellow>100.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>C=75 M=0 Y=100 K=0</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>75.000000</xmpG:cyan>
+                           <xmpG:magenta>0.000000</xmpG:magenta>
+                           <xmpG:yellow>100.000000</xmpG:yellow>
+                           <xmpG:black>0.000000</xmpG:black>
+                        </rdf:li>
+                        <rdf:li rdf:parseType="Resource">
+                           <xmpG:swatchName>C=85 M=10 Y=100 K=10</xmpG:swatchName>
+                           <xmpG:mode>CMYK</xmpG:mode>
+                           <xmpG:type>PROCESS</xmpG:type>
+                           <xmpG:cyan>85.000000</xmpG:cyan>
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+                           <xmpG:black>10.000002</xmpG:black>
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+                           <xmpG:mode>CMYK</xmpG:mode>
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+                           <xmpG:cyan>90.000000</xmpG:cyan>
+                           <xmpG:magenta>30.000002</xmpG:magenta>
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+                           <xmpG:cyan>80.000000</xmpG:cyan>
+                           <xmpG:magenta>10.000002</xmpG:magenta>
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