Using the gui for latex2rtf v.1.9.19 + l2rshell v0.5.2 (on windows 7, I downloaded the precompiled version)
When using a filename (tex file) with spaces it will say latex2rtf will only support 1 file. The reason is that the file name isn't encapsulated in quotes so it sees the file name as multiple arguments.
Also found in LaTeX2rtf v2.1.1 + l2shell v0.6.3
works in the unix version