Search Results for "multiple sequence alignment" - Page 6
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Showing 231 open source projects for "multiple sequence alignment"
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FOCUS
A model to identify organisms present in metagenomes in seconds
...Cite FOCUS Silva, G. G. Z., D. A. Cuevas, B. E. Dutilh, and R. A. Edwards, 2014: FOCUS: an alignment-free model to identify organisms in metagenomes using non-negative least squares. PeerJ, 2, e425,doi:10.7717/peerj.425. -
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The Maltcms - Modular Application Toolkit for Chromatography Mass-Spectrometry is a JAVA API for preprocessing, alignment, analysis and visualization of data stored in open file formats used in Proteomics and Metabolomics research.
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FOCUS2
FOCUS2: agile metagenomic classificication using reduced DB
Summary: Metagenomics approaches rely on identifying the presence of organisms in the microbial community from a set of unknown DNA sequences. Sequence classification has valuable applications in multiple important areas of medical and environmental research. Here we introduce FOCUS2, an update of the previously published computational method FOCUS. FOCUS2 was tested with 10 simulated and 543 real metagenomes demonstrating that the program is more sensitive, faster, and more computationally efficient than existing methods -
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CoverageAnalyzer
RNA modification detection by RT signatures in deep sequencing data
Combination of reverse transcription (RT) and deep sequencing has emerged as a powerful instrument for detection of RNA modifications, a field that has seen a recent surge in activity because of its importance in gene regulation. Recent studies yielded high-resolution RT signatures relying on both, sequence dependent mismatch patterns and RT arrests. Common alignment viewers lack in specialized functionality, such as filtering, tailored visualization, differential analysis and export. Consequently, the community will profit from a platform seamlessly connecting detailed visual inspection of RT signatures and automated screening for modification candidates. ... -
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EvalMSA
Perl-based tool for evaluating multiple sequence alignments
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CATO Clone Alignment Tool
Identifies clone sequences corresponding to set of reference sequences
Specialized sequence alignment software that helps associate the most likely matches of clone sequences to a set of reference sequences. Both sets of sequences are assumed to be nucleotides. -
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Faligner
Faligner: a Local Sequence Alignment Ubuntu Package
A package based on 3 local alignment tools i.e., Bowtie, Bowtie2 and BWA. Package covers single-end, paired-end alignments. Moreover, the package also demonstrates overlap alignment and colorspace alignment features. The package also includes graphical user interface to make it interactive. -
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geneslider
Gene Slider for Alignment Visualisation
Gene Slider can be used to visualize conservation and entropy of aligned DNA and protein sequences by presenting them as one long sequence logo. The presented sequence logo can be zoomed in and out. It can also display motifs in alignments. A built-in search function can be used to find motifs. Gene Slider is available online on the Bio-Analytic Resource and for download here. -
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MeSeq is a package providing ease in installing some popular Multiple Sequence Alignment Tools. It also provides a GUI interface for the tools.
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Mauve computes and interactively visualizes genome sequence comparisons. Using FastA or GenBank sequence data, Mauve constructs multiple genome alignments that identify large-scale rearrangement, gene gain, gene loss, indels, and nucleotide substutit
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Protospacer Workbench
CRISPR/Cas9 guide-RNA design
Protospacer Workbench helps to design, analyze, and share CRISPR target-sites for any organism or set of FASTA formatted sequences. Design of guide-RNAs for the CRISPR/Cas genome editing system is intuitively easy, but computationally difficult. The main difficulty arises from the need to identify potential off-targets that may be quite different from the intended target. Current online tools for guide-RNA design provide a user friendly interface to sequence mapping software such as... -
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PROMOT
A tool for finding functional motifs from aligned protein sequences
PROMOT (version 4.0) is a bioinformatics tool for discovering motifs (in the PROSITE format) from a set of aligned sequences. To run the tool, you need to have Java 8 installed on your system. Download and execute the JAR without any parameters to know about how to use the tool. A sample alignment of 91 protein sequences is also provided in the file "aligned.fasta". A sample run of the tool can be seen by using the following command: java -jar promot4.jar 70 2 n aligned.fasta >... -
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This tool helps you to reverse engineer UML Sequence Diagram for your java program at runtime. It works well with both complex java programs (that have multiple threads) and J2EE applications deployed on Application Servers.
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Grinder is a versatile open-source bioinformatic tool to create simulated omic shotgun and amplicon sequence libraries for all main sequencing platforms.
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Software for visualization of point variability in pairwise sequence alignment FASTA format. Featuring GUI interface, this simple application enables insight into variation of nucleic and amino acids on specific loci. Current 1.1 version supports amino and nucleic acid alignments. There are 2 variations of this software. One is CLI based and the other one is GUI based. Read corresponding README files in order to get familiar with the software.
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vim-easy-align
A Vim alignment plugin
vim-easy-align is a Vim/Neovim plugin that makes it simple to align text by a pattern, character, or regular expression across a selection or motion. Instead of hand-inserting spaces and fiddling with tabs, you select lines and invoke an interactive prompt that previews the alignment as you type the rule. It supports multiple delimiters—commas, colons, equals signs, pipes—and can align on the nth occurrence or on complex regex groups. The plugin is designed to be composable with normal Vim workflows, working in visual mode or with motions, and honoring your indentation and tab settings. It also offers left, right, and center alignment, plus padding and justification control, so tables, hashes, assignment lists, and Markdown fragments look neat. ... -
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REDHORSE
Software suite for the analysis of haploid hybrids using NGS
The alignments to the genome from next-generation-sequencing (NGS) data cannot be directly used as input to the existing recombination detection (RD) algorithms that use multiple sequence alignments (MSA). We therefore designed a software suite called REDHORSE that takes genomic alignments as input, extracts meaningful markers and generates MSAs that are the inputs to existing RD algorithms. In addition, REDHORSE implements a custom RD algorithm that makes use of sequence information and genomic positions to accurately detect crossovers. ... -
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MicroRNA_alignment_evaluation
MicroRNA alignment Supporting Data
The scripts and sequence files deposited here are supporting information to our recently submitted paper that investigates the accuracy of NGS aligners for microRNA studies. -
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StockSims Inspector Simulator
StockSims Inspector Simulator
Stock Price Inspector Moon Phase Alignment Inspection Trading Simulation Engine Key View (Multiple Time Frame Comparator) -
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...Both images with single spot groups and multiple spot groups (372 and 324 spots/group) can be processed. Example of such images were taken from the GEO and SMD databases. e.g., GSM102718 - GEO experiment for single spot group.
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CEMAsuite
Consensus/Degenerate Primer Design Application
CEMAsuite, is an interactive Java-based application with the ability to (i) construct a codon-equivalent multiple alignment (CEMA) from a protein multiple sequence alignment (MSA) file, (ii) generate and score each position in the consensus DNA sequence using multiple algorithms, (iii) design single-degeneracy primer backbones using Primer3 (Untergasser et al. 2012), (iv) estimate the stability of degenerate primers on each of the coding sequences within the CEMA, and (v) export intermediate results in various formats. ... -
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LowMACA
Low frequency Mutation Analysis via Consensus Alignment
...However, we are still far from a complete picture of rarely mutated genes, which can be an important target for personalized medicine. To overcome this difficulty, we have implemented LowMACA (Low frequency Mutation Analysis via Consensus Alignment), a new method able to assess specific characteristics of rarely mutated genes that show patterns of positive selection. LowMACA aggregates and analyzes the mutational patterns of several genes whose encoded proteins have a high level of sequence similarity or share specific protein domains. -
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Matplotlib tutorial
Matplotlib tutorial for beginner
...As the tutorial builds progressively, learners can gradually advance from simple static plots to more complex visualizations, learning how to control figure size, add multiple subplots, adjust plot aesthetics, and handle different data types. Because it is code-first, users can copy, modify, and run the examples on their own datasets, encouraging experimentation and deepening understanding. -
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AlignMerger
A tool for merging two large multiple sequence alignments
AlignMerger is useful to merge two sets of multiple sequence alignments (MSA). It can greatly reduce the computational time needed to construct a MSA, compare to others commonly used MSA tools. Inputs required for the tool are two MSAs in FASTA format and output of the tool is a merged MSA in FASTA format. -
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Maximum Common Genome Alignment (MCGA)
Pipeline for creating core genome alignments for phylogenetic analysis
Maximum Common Genome Alignment (MCGA) Tool MCGA is a bioinformatics analysis tool written in Python for generating core genome alignment for bacterial whole genome sequences which can be used to construct phylogenetic trees.
