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High-performance read alignment, quantification and mutation discovery
... in the following paper: Yang Liao, Gordon K Smyth and Wei Shi. "The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote", Nucleic Acids Research, 2013, 41(10):e108
A CLI tool for k-mer counting with all possible sizes of k at once
Universal-Mer is a k-mer counting tool for all possible size of k at once. More than typical k-mer counting tools, the program can summarize the exact counting result of 1-mers to l-mers at once where l = the length of longest repeated substring in the input sequence where now the maximum length is set to 100000-mers. The program can report exactly the number of all repeat (freq>1) and unique(freq = 1) mers , and the number of all possible substrings of sequences without cutting off any low...
In general, Pearson correlation coefficients can be quite error-prone to outliers, thus Jackknifing may be helpful. I could not find any useful implementation for calculating more than leave-1-out Jackknife Pearson correlation coefficients. 'leave-kojack' offers an implementation for Jackknife Pearson correlation with dynamic values of k, i.e. leave-k-out Pearson correlation.
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... interaction analysis for binary traits.
Here we present a novel software package GENIE, which utilizes the power of multiple GPU or CPU processor cores to parallelize the interaction analysis.
Citation: Chikkagoudar, S., Wang, K., & Li, M. (2011). GENIE: a software package for gene-gene interaction analysis in genetic association studies using multiple GPU or CPU cores. BMC research notes, 4(1), 158.
parastructure is a perl script collection to run the population genetics software STRUCTURE from Pritchard et al. 2000 (http://pritch.bsd.uchicago.edu/structure.html) in parallel on a cluster (beowulf type). Each run of K (the number of populations) is executed separately on each CPU of the cluster trough queue system based on PBS.
A summary statistics table and distruct figures (Noah Rosenberg: http://www.stanford.edu/group/rosenberglab/distruct.html) are built at the end of the run.
A patch...
FFP (Feature frequency profile) is an alignment free comparison tool for phylogenetic analysis and text comparison. It can be applied to nucleotide sequences, complete genomes, proteomes and even used for text comparison.
This tool is designed to solve generalized pattern matching problem, by which we only find a set of sub-patterns, ignoring the gaps in between the sub-patterns. This tool is extremely fast and also has good tolerance to errors.
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Basic implementation of K-nearest neighbour Algorithm and the application of KNN to classify protein sequences as transmembrane beta barrel or non-transmembrane beta barrel on the basis of whole sequence amino acid composition given as input.