Showing 268 open source projects for "seq"

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  • 1

    MethyMer

    Design of specific primer combinations for bisulfite sequencing

    ...) and gene expression (RNA-Seq) data, as well as methylation-expression correlation analysis results for 20 human cancer types. ENCODE genome regions annotation data are also integrated in MethyMer
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  • 2

    dnase2tf_R

    dnase2tf finds footprint candidates from the DNase-I seq data

    dnase2tf finds footprint candidates from the DNase-I seq data (given by datafilepath) on the user specified regions of interest (given by hotspotfilename). Mappability file location (mapfiledir) and the filename for the output file are also required.
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  • 3
    gogadget

    gogadget

    A toolbox for interpretation and visualization of RNA-seq GO analysis

    gogadget is an R package, and can help with the visualization and interpretation of GO enrichment analysis of RNA-seq data. It is developed especially for the use in combination with goseq. The functions that are available in this package are extensively described in the user's guide. To install the package download the "gogadget_2.1.tar.gz" file, open R and install with the following line: install.packages( "C:/your/directory/gogadget_2.1.tar.gz", repos = NULL, type="source") The package...
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  • 4
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    wechat4u.js

    wechat4u.js

    JavaScript implementation of WeChat wechat web interface

    ... avatar base64 data is no longer stored in the bot.user object. Rremove the example directory. Fix some data in Contact and Message data is not enumerable. Pass the complete Error object to the upper-level code, and put the original Chinese error description in err.tips. The bot.getContact(Seq) method adds the Seq parameter to support incremental acquisition of complete contacts.
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  • 6

    meerkat.sh

    script of SV calling in Exome-seq

    meerkat.sh is a shell script to run Meerkat for SV detection in Exome-seq. The script accepts single BAM or paired tumor-normal BAMs.
    Downloads: 1 This Week
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  • 7

    fourSig

    Analyze 4C-seq data.

    fourSig is a suite of programs for analyzing and visualizing 4C-seq data.
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  • 8
    CSBB-v2.0

    CSBB-v2.0

    Computational Suite for Bioinformaticians and Biologists

    ... and Windows platforms. Currently CSBB provides 16 modules focused on analytical tasks like normalization, visualization, statistics, RNA-SEQ etc.
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  • 9

    Crosshub

    Multi-way analysis of The Cancer Genome Atlas (TCGA) project datasets

    Crosshub enables multi-way analysis of RNA-Seq, miRNA-Seq and methylome data of The Cancer Genome Atlas (TCGA) project: 1. differential expression analysis (genes, alternative transcripts and miRNA) 2. regulatory miRNA prediction (TargetScan, DIANA microT, mirSVR, PicTar, miRTarBase + co-expression) 3. regulatory TF prediction (ENCODE ChIP-Seq + co-expression) 4. methylation profiling analysis 5. RNA-Seq vs. clinical (TNM, stage, follow-up) correlation analysis Generates Excel summaries...
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  • 10

    SnowyOwl

    RNA-Seq based gene prediction pipeline for fungal genomes

    SnowyOwl is a gene prediction pipeline that uses RNA-Seq data to train and provide hints for the generation of Hidden Markov Model (HMM)-based gene predictions, and to evaluate the resulting models. The pipeline has been validated and streamlined by comparing its predictions to manually curated gene models in three fungal genomes, and its results show substantial increases in sensitivity and selectivity over previous gene predictions. Sensitivity is gained by repeatedly running the HMM gene...
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  • 11

    ChiPSeqPair

    Match Chip-Seq Data with different features

    1. Match Chip-Seq Data with different features 2. Match Chip-Seq Data with input data 3. Find Seq information to facilitate download and analysis of Chip-seq data
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  • 12
    SUPERmerge

    SUPERmerge

    ChIP-seq coverage island analysis algorithm for broad histone marks

    SUPERmerge is a ChIP-seq read pileup analysis and annotation algorithm for investigating alignment (BAM) files of diffuse histone modification ChIP-seq datasets with broad chromatin domains at a single base pair resolution level. SUPERmerge allows flexible regulation of a variety of read pileup parameters, thereby revealing how read islands aggregate into areas of coverage across the genome and what annotation features they map to within individual biological replicates. SUPERmerge...
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  • 13
    RUbioSeq
    The increasing demand of next-generation sequencing (NGS) studies has remarked the necessity of integrated and reliable pipelines to analyse deep-sequencing experiments in an efficient way. We present RUbioSeq+, a stand-alone and multiplatform application for the integrated analysis of NGS data. More specifically, our software implements pipelines for the analysis of single nucleotide and copy-number variation, bisulfite-seq and ChIP-seq experiments using well-established tools to perform...
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  • 14

    ImReP

    Immune repertoire assembly from RNA-Seq data

    ImReP is a tool written in Python programming language (version 2.7) which is designed to assemble CDR3 region sequences from RNA- or TCR-(BCR-)-Seq reads (either single- or paired-end) and provide immune repertoire as a set of clonotypes with their counts.
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  • 15
    QuickRNASeq

    QuickRNASeq

    A pipeline for large scale RNA-seq data analysis

    We have implemented QuickRNASeq, an open-source based pipeline for large scale RNA-seq data analysis. QuickRNASeq takes advantage of parallel computing resources, a careful selection of previously published algorithms for RNA-seq read mapping, counting and quality control, and a three-stage strategy to build a fully automated workflow. We also implemented built-in functionalities to detect sample swapping or mislabeling in large-scale RNA-seq studies. Our pipeline significantly lifts large...
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  • 16
    Zika-RNAseq-Pipeline

    Zika-RNAseq-Pipeline

    An open RNA-Seq data analysis pipeline tutorial

    RNA-seq analysis is becoming a standard method for global gene expression profiling. However, open and standard pipelines to perform RNA-seq analysis by non-experts remain challenging due to the large size of the raw data files and the hardware requirements for running the alignment step. Here we introduce a reproducible open source RNA-seq pipeline delivered as an IPython notebook and a Docker image. The pipeline uses state-of-the-art tools and can run on various platforms with minimal...
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  • 17
    PoPoolation2 allows to compare allele frequencies for SNPs between two or more populations and to identify significant differences. PoPoolation2 requires next generation sequencing data of pooled genomic DNA (Pool-Seq). It may be used for measuring differentiation between populations, for genome wide association studies and for experimental evolution. Documentation: https://sourceforge.net/p/popoolation2/wiki/Main/
    Downloads: 4 This Week
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  • 18
    MaxInfo

    MaxInfo

    Transcriptome assembler for RNA-seq

    MaxInfo is an automated transcript discovery and quantification software designing for high-throughput RNA sequencing (RNA-seq). Assembling transcripts from reads are challenging because of the unpredictable uncertainties arising from completing full genome structure with very partial observations. MaxInfo tackles this problem by explicitly reducing the inherent uncertainties in the biological system caused by missing information.
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  • 19

    ROP : Read origin protocol

    ROP is a computational protocol to discover the source of all reads

    ... output by our method is not limited to RNA-Seq technology and may be applied to whole-exome and whole-genome sequencing. For more details see: https://sergheimangul.wordpress.com/rop/ ROP Tutorial: https://github.com/smangul1/rop/wiki
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  • 20
    ViralFusionSeq [VFS]

    ViralFusionSeq [VFS]

    Accurately discover viral integration events and fusion transcripts

    VFS was fullly tested under Ubuntu/Debian system. ** Announcement 1**: VFS is superior to Virus-Clip. https://sourceforge.net/projects/viralfusionseq/files/VFS.vs.Virus-Clip.pdf/download As of 2016, VFS is the only viral integration tool available at NIH HPC system. https://hpc.nih.gov/apps/ViralFusionSeq/ ViralFusionSeq (VFS) is a versatile high-throughput sequencing (HTS) tool for discovering viral integration events and reconstruct fusion transcripts at single-base resolution. VFS...
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  • 21

    EpiMINE

    program for mining epigenomic data

    EpiMINE is a program designed for mining epigenomic data. This application performs genome wide based quantitative and correlative analysis between different annotated or raw chip-seq like datasets in the regions of interest (RI). Apart from this the tool takes the advantage in linking results with expression data. It is available both in graphical user interface and in command line form. It can be executed in Mac and Linux platforms. Dependencies: python >= 2.7 version python packages: rpy2...
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  • 22

    ngs-suite

    A set of NGS tools for DNA-seq and BS-seq

    ngs-suite aims is to collect a set of fast and well written C++11 software to handle analysis and manipulation of NGS short reads. It works with DNA-seq and BS-seq data.
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  • 23

    PeaksAndValleys

    Peaks and Valley detection using NGS data

    Active regulatory elements in eukaryotic genomes are typically associated with nucleosome-depleted regions that are hypersensitive to digestion by nonspecific endonucleases. Techniques which distinguish active regulatory elements by virtue of this include micrococcal nuclease digestion of chromatin (MNAse-seq), which preferentially depletes DNA which is not tightly bound by proteins, and formaldehyde-assisted isolation of regulatory elements (FAIRE-seq), which enriches for sequences which...
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  • 24
    riboFR-seq

    riboFR-seq

    A novel approach to linking 16S rRNA amplicon profiles to metagenomes

    16S rRNA amplicon analysis and shotgun metagenome sequencing are two main culture-independent strategies to explore the genetic landscape of various microbial communities. Recently, numerous studies have employed these two approaches together, but downstream data analyses were performed separately, which always generated incongruent or conflict signals on both taxonomic and functional classifications. Here we propose a novel approach, RiboFR-Seq (Ribosomal RNA gene Flanking Region Sequencing...
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  • 25

    ISVASE

    identification of sequence variant associated with splicing event

    To generate correct mature mRNAs, the exons must be identified and joined together precisely and efficiently by RNA splicing mechanism. It is to be noted that about one third or a half of all disease-causing mutations effect RNA splicing. However, there is little bioinformatics tools to directly identify sequence variants associated with splicing events (SVASE) based on RNA-seq data. We developed ISVASE, a simple and convenient tool for identifying SVASE directly using RNA-seq data. Comparing...
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