From: Alec W. <al...@br...> - 2011-07-26 15:01:52
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Hi Ryan, We are running MarkDuplicates on RNA-seq data. I don't think there is any reason to assume there won't be the same PCR and optical duplication issues that exist for DNA (but I'm just a s/w developer, not a biologist). The usual caveats apply that MarkDuplicates works much better on paired reads. -Alec On 7/26/11 10:53 AM, Ryan Golhar wrote: > Hi all - I'm analyzing some RNA-Seq data and was wondering about > running MarkDups on it to remove duplicate reads. Does this seem like > something reasonable to do or is MarkDups not necessary for RNA-Seq data? > > > ------------------------------------------------------------------------------ > Magic Quadrant for Content-Aware Data Loss Prevention > Research study explores the data loss prevention market. Includes in-depth > analysis on the changes within the DLP market, and the criteria used to > evaluate the strengths and weaknesses of these DLP solutions. > http://www.accelacomm.com/jaw/sfnl/114/51385063/ > > > _______________________________________________ > Samtools-help mailing list > Sam...@li... > https://lists.sourceforge.net/lists/listinfo/samtools-help |