GritstoneGritstone bio
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SpliceCoreEnvisagenics
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Related Products
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About
The first pillar of our immunotherapy is our understanding of antigens and neoantigens, and specifically which ones will be transcribed, translated, processed and presented on a cell surface by Human leukocyte antigen (HLA) molecules; and therefore will be visible to T cells. We accomplish this through the use of Gritstone EDGETM, our proprietary machine learning-based platform. Developing cancer immunotherapies that include tumor-specific neoantigens presents a challenge due to their nature – tumors typically have hundreds of mutations, but only a small percentage of those mutations result in true tumor-specific neoantigens that are. To address this challenge, we trained EDGE’s novel integrated neural network model architecture with millions of data points from hundreds of tumor and normal tissue samples from patients of various ancestries.
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About
Using RNA sequencing (RNA-seq) data and Artificial Intelligence are both a necessity and an opportunity to develop therapeutics that target splicing errors. The use of machine learning enables us to discover new splicing errors and quickly design therapeutic compounds to correct them. SpliceCore is our dedicated AI platform for RNA therapeutics discovery. We developed this technology platform specifically for the analysis of RNA sequencing data. It can identify, test and validate hypothetical drug targets faster than traditional methods. At the heart of SpliceCore is our proprietary database of more than 5 million potential RNA splicing errors. It is the largest database of splicing errors in the world and it is used to test every RNA sequencing dataset that is input for analysis. Scalable cloud computing enables us to process massive amounts of RNA sequencing data efficiently, at higher speed and lower cost, exponentially accelerating therapeutic innovation.
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Platforms Supported
Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook
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Platforms Supported
Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook
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Audience
Anyone looking for a scientific platform that helps with accurate identification of antigens
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Audience
Labs seeking an AI platform to generate a volume of insights comparable to years of traditional drug target discovery
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Support
Phone Support
24/7 Live Support
Online
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Support
Phone Support
24/7 Live Support
Online
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API
Offers API
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API
Offers API
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Pricing
No information available.
Free Version
Free Trial
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Pricing
No information available.
Free Version
Free Trial
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Reviews/
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Training
Documentation
Webinars
Live Online
In Person
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Training
Documentation
Webinars
Live Online
In Person
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Company InformationGritstone bio
Founded: 2015
United States
gritstonebio.com/scientific-platform/
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Company InformationEnvisagenics
Founded: 2014
United States
www.envisagenics.com/platform/
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Integrations
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Integrations
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