Audience

Anyone looking for a scientific platform that helps with accurate identification of antigens

About Gritstone

The first pillar of our immunotherapy is our understanding of antigens and neoantigens, and specifically which ones will be transcribed, translated, processed and presented on a cell surface by Human leukocyte antigen (HLA) molecules; and therefore will be visible to T cells. We accomplish this through the use of Gritstone EDGETM, our proprietary machine learning-based platform. Developing cancer immunotherapies that include tumor-specific neoantigens presents a challenge due to their nature – tumors typically have hundreds of mutations, but only a small percentage of those mutations result in true tumor-specific neoantigens that are. To address this challenge, we trained EDGE’s novel integrated neural network model architecture with millions of data points from hundreds of tumor and normal tissue samples from patients of various ancestries.

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Company Information

Gritstone bio
Founded: 2015
United States
gritstonebio.com/scientific-platform/

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Product Details

Platforms Supported
Cloud
Support
Online

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Gritstone Product Features