Evo 2

Evo 2

Arc Institute
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+

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About

Evo 2 is a genomic foundation model capable of generalist prediction and design tasks across DNA, RNA, and proteins. It utilizes a frontier deep learning architecture to model biological sequences at single-nucleotide resolution, achieving near-linear scaling of compute and memory relative to context length. Trained with 40 billion parameters and a 1 megabase context length, Evo 2 processes over 9 trillion nucleotides from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function prediction across multiple biological modalities, including DNA, RNA, and proteins, and to generate novel sequences with plausible genomic architecture. The model's capabilities have been demonstrated in tasks such as designing functional CRISPR systems and predicting disease-causing mutations in human genes. Evo 2 is publicly accessible via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework.

About

Portable Computer is a local-first version of Perplexity Computer that runs entirely on your own machine, keeping private data on-device while still supporting complex agentic workflows. Built with NVIDIA, it runs the orchestrator, planner, tool router, scheduler, durable task queue, local search index, and AI models locally, so it can analyze data, synthesize files, search documents and code, take actions on the device, and keep long-running jobs active without relying on the cloud. It runs on NVIDIA DGX Spark with Qwen 3.8 27B or PPLX 27B, with NVIDIA Nemotron 3.5 Lightning coming to the model picker. It is trained to complete as much of each task locally as possible and can escalate only the steps that need current information, browser access, connected apps, or frontier reasoning. When a task needs to send content from the device to a cloud service, Portable Computer asks for permission before proceeding.

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Audience

Computational biologists and genetic engineers in need of a tool to model and design biological sequences across multiple modalities, enhancing research in genomics and synthetic biology

Audience

Privacy-conscious professionals, developers, and AI users seeking to run complex AI agent workflows locally while keeping sensitive files and data on their own hardware

Support

Phone Support
24/7 Live Support
Online

Support

Phone Support
24/7 Live Support
Online

API

Offers API

API

Offers API

Screenshots and Videos

Screenshots and Videos

Pricing

No information available.
Free Version
Free Trial

Pricing

$20 per month
Free Version
Free Trial

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

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Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Training

Documentation
Webinars
Live Online
In Person

Training

Documentation
Webinars
Live Online
In Person

Company Information

Arc Institute
United States
arcinstitute.org/tools/evo

Company Information

Perplexity
Founded: 2022
United States
www.perplexity.ai/hub/products/portable-computer

Alternatives

Alternatives

Evo Designer

Evo Designer

Arc Institute
Nemotron 3

Nemotron 3

NVIDIA
ESMC

ESMC

Biohub

Categories

Categories

Integrations

GitHub
Asana
Dropbox
Evo Designer
Gmail
Google Drive
Hugging Face
Jira
Linear
Microsoft Excel
Microsoft OneDrive
Microsoft Teams
NVIDIA BioNeMo
Nemotron 3.5 Lightning
Notion
Perplexity Search API
Slack
Snowflake

Integrations

GitHub
Asana
Dropbox
Evo Designer
Gmail
Google Drive
Hugging Face
Jira
Linear
Microsoft Excel
Microsoft OneDrive
Microsoft Teams
NVIDIA BioNeMo
Nemotron 3.5 Lightning
Notion
Perplexity Search API
Slack
Snowflake
Claim Evo 2 and update features and information
Claim Evo 2 and update features and information
Claim Portable Computer by Perplexity and update features and information
Claim Portable Computer by Perplexity and update features and information