Evo 2

Evo 2

Arc Institute
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+

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About

Evo 2 is a genomic foundation model capable of generalist prediction and design tasks across DNA, RNA, and proteins. It utilizes a frontier deep learning architecture to model biological sequences at single-nucleotide resolution, achieving near-linear scaling of compute and memory relative to context length. Trained with 40 billion parameters and a 1 megabase context length, Evo 2 processes over 9 trillion nucleotides from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function prediction across multiple biological modalities, including DNA, RNA, and proteins, and to generate novel sequences with plausible genomic architecture. The model's capabilities have been demonstrated in tasks such as designing functional CRISPR systems and predicting disease-causing mutations in human genes. Evo 2 is publicly accessible via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework.

About

Genome Computer turns your genetic data into a portable, AI-ready .genome bundle you can download, keep, self-host, and explore with Genome Intelligence, Codex, Claude Code, Cursor, or any compatible tool. The open format restructures the same underlying data found in a VCF into a structured, queryable bundle, with variants stored in fast columnar tables alongside trait associations, supporting research, gene-level context, polygenic scores, pharmacogenomics, and clear provenance. Whole-genome sequencing orders are built from gVCF data, preserving both detected variants and confidently sequenced regions where no variant was found, while FASTQ files are available on request. Existing VCF or TXT files from other providers can also be converted, imputed where needed, annotated, scored, and prepared for AI interpretation. Genome Intelligence lets you ask questions grounded in your actual genetic data, compare new research with your genotypes, and explore genetics.

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported

Audience

Computational biologists and genetic engineers in need of a tool to model and design biological sequences across multiple modalities, enhancing research in genomics and synthetic biology

Audience

Individuals and developers seeking to privately explore genomic data and generate AI-powered insights without surrendering control of their genetic information

Support

Phone Support Not Supported
24/7 Live Support Not Supported
Online Supported

Support

Phone Support Supported
24/7 Live Support Not Supported
Online Supported

API

Offers API Not Supported

API

Offers API Supported

Screenshots and Videos

Screenshots and Videos

Pricing

No information available.
Free Version Not Supported
Free Trial Not Supported

Pricing

$15 per month
Free Version Not Supported
Free Trial Not Supported

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Supported

Training

Documentation Supported
Webinars Not Supported
Live Online Supported
In Person Not Supported

Company Information

Arc Institute
United States
arcinstitute.org/tools/evo

Company Information

Genome Computer
United States
genome.computer/

Alternatives

Alternatives

Evo Designer

Evo Designer

Arc Institute
ESMC

ESMC

Biohub
GenomeStudio

GenomeStudio

Illumina

Categories

AI Models Supported
AI Science Supported
Bioinformatics Supported
Foundation Models Supported
Molecular Modeling Supported

Categories

AI Science Supported

Integrations

Claude Code Not Supported
Cursor Not Supported
Evo Designer Supported
GitHub Supported
Hugging Face Supported
NVIDIA BioNeMo Supported
OpenAI Codex Not Supported

Integrations

Claude Code Supported
Cursor Supported
Evo Designer Not Supported
GitHub Not Supported
Hugging Face Not Supported
NVIDIA BioNeMo Not Supported
OpenAI Codex Supported
Claim Evo 2 and update features and information
Claim Evo 2 and update features and information
Claim Genome Computer and update features and information
Claim Genome Computer and update features and information