Claude Opus 5.5

Claude Opus 5.5

Anthropic
ESMFold

ESMFold

Meta
+
+

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About

Claude Opus 5.5 is Anthropic’s advanced AI model for agentic coding, complex knowledge work, computer use, research, and long-running professional tasks. It is designed to handle large codebases, multi-step workflows, financial analysis, document creation, software audits, and other demanding workloads with improved efficiency over Claude Opus 5. Anthropic reports that Opus 5.5 uses fewer tokens per task, produces output more than 30% faster, and costs less to run than its predecessor. The model also improves communication quality by putting important information first, reducing unnecessary jargon, and following writing instructions more consistently. Safety enhancements include stronger prompt-injection resistance, action screening, sandboxing support, code review, behavioral alignment testing, and safeguards for high-risk cybersecurity & biology. Claude Opus 5.5 is available through Claude, Claude Code, the Claude Platform API, Amazon Web Services, Google Cloud, and Microsoft Azure.

About

ESMFold shows how AI can give us new tools to understand the natural world, much like the microscope, which enabled us to see into the world at an infinitesimal scale and opened up a whole new understanding of life. AI can help us understand the immense scope of natural diversity, and see biology in a new way. Much of AI research has focused on helping computers understand the world in a way similar to how humans do. The language of proteins is one that is beyond human comprehension and has eluded even the most powerful computational tools. AI has the potential to open up this language to our understanding. Studying AI in new domains such as biology can also give insight into artificial intelligence more broadly. Our work reveals connections across domains: large language models that are behind advances in machine translation, natural language understanding, speech recognition, and image generation are also able to learn deep information about biology.

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported

Audience

Software developers, AI engineers, researchers, analysts, legal and financial professionals, enterprises, and other organizations that need a high-capability model for coding, knowledge work, computer use, and long-running agentic workflows

Audience

Researchers interested in a language model for proteins and genomics

Support

Phone Support Not Supported
24/7 Live Support Not Supported
Online Supported

Support

Phone Support Not Supported
24/7 Live Support Not Supported
Online Not Supported

API

Offers API Supported

API

Offers API Not Supported

Screenshots and Videos

Screenshots and Videos

Pricing

$4 per 1M tokens (input)
$4 per million input tokens and $20 per million output tokens.

Cache reads, which account for most costs in agentic and coding workloads, are priced at just $0.20 per million tokens which is 60% cheaper than Opus 5. Opus 5.5 also delivers output over 30% faster than its predecessor.
Free Version Not Supported
Free Trial Not Supported

Pricing

Free
Free Version Supported
Free Trial Not Supported

Reviews/Ratings

Overall 5.0 / 5
ease 5.0 / 5
features 5.0 / 5
design 5.0 / 5

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Pros & Cons from Real Users

Pros

  • After using it, the biggest thing I notice is how much better it is at sustained work. It stays organized across long coding sessions, multi-file changes, research tasks, and agent workflows without needing nearly as much babysitting. The coding performance is excellent. Anthropic reports 54.6% on FrontierCode 1.1 at default effort, ahead of GPT-6 Astra’s reported 53.3%, and I can see why. It is especially good at understanding a large task, making sensible changes, and avoiding unnecessary edits. I also really like the efficiency. At $4 per million input tokens and $20 per million output tokens, plus much cheaper cache reads, Opus 5.5 is easier to use heavily than Opus 5. Anthropic says typical workloads come out around 40% cheaper overall. Another improvement is the writing. It is noticeably less verbose and easier to follow, which matters a lot during long sessions when I need to quickly understand what the model changed and why.

Cons

  • The main downside is that it is still a premium model, so I would not waste it on every trivial task. And like any coding agent, I still review diffs, run tests, and keep permissions tight.

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Not Supported

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Not Supported

Company Information

Anthropic
Founded: 2021
United States
claude.ai

Company Information

Meta
Founded: 2004
United States
github.com/facebookresearch/esm

Alternatives

Alternatives

GPT-3.5

GPT-3.5

OpenAI
Claude Fable 5

Claude Fable 5

Anthropic
ESMC

ESMC

Biohub

Categories

AI Coding Models Supported
AI Models Supported
AI Vision Models Supported
Foundation Models Supported
Multimodal Models Supported

Categories

AI Models Supported
Generative AI Supported

Integrations

CSS Supported
Claude Science Supported
Claude Security Supported
Cosmos Supported
Dart Supported
DataGrip Supported
Devin Desktop Supported
Emergent Supported
Flowise Supported
GitHub Copilot CLI Supported
JavaScript Supported
Microsoft Foundry Supported
MyClaw Supported
Python Supported
Scala Supported
Simtheory Supported
Thread Deck Supported
TypeScript Supported
Vellum Supported
Zo Computer Supported

Integrations

CSS Not Supported
Claude Science Not Supported
Claude Security Not Supported
Cosmos Not Supported
Dart Not Supported
DataGrip Not Supported
Devin Desktop Not Supported
Emergent Not Supported
Flowise Not Supported
GitHub Copilot CLI Not Supported
JavaScript Not Supported
Microsoft Foundry Not Supported
MyClaw Not Supported
Python Not Supported
Scala Not Supported
Simtheory Not Supported
Thread Deck Not Supported
TypeScript Not Supported
Vellum Not Supported
Zo Computer Not Supported
Claim Claude Opus 5.5 and update features and information
Claim Claude Opus 5.5 and update features and information
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