Audience
Researchers interested in a language model for proteins and genomics
About ESMFold
ESMFold shows how AI can give us new tools to understand the natural world, much like the microscope, which enabled us to see into the world at an infinitesimal scale and opened up a whole new understanding of life. AI can help us understand the immense scope of natural diversity, and see biology in a new way. Much of AI research has focused on helping computers understand the world in a way similar to how humans do. The language of proteins is one that is beyond human comprehension and has eluded even the most powerful computational tools. AI has the potential to open up this language to our understanding. Studying AI in new domains such as biology can also give insight into artificial intelligence more broadly. Our work reveals connections across domains: large language models that are behind advances in machine translation, natural language understanding, speech recognition, and image generation are also able to learn deep information about biology.
Other Popular Alternatives & Related Software
Claude Fable 5.2
Claude Fable 5.2 is an advanced AI reasoning model developed by Anthropic for complex software engineering, scientific research, technical problem-solving, and autonomous agent workflows. The model provides improvements in coding, mathematical reasoning, visual understanding, and long-running task execution compared with previous Claude Fable models. Its agentic capabilities allow AI systems to analyze large codebases, coordinate multiple subagents, develop software, investigate technical problems, and automate complex business processes. Claude Fable 5.2 generates outputs up to 30% faster than Fable 5.1 and offers an optional fast mode that increases generation speed by up to 2.5 times. The model includes configurable reasoning effort, advanced tool use, and specialized cybersecurity and biology safeguards designed to reduce misuse while supporting general technical work.
Learn more about Claude Fable 5.2
GPT-5.6 Sol
GPT-5.6 Sol is a next-generation OpenAI model designed for advanced reasoning, coding, agentic workflows, biology analysis, cybersecurity support, and complex knowledge work. It is part of the GPT-5.6 model family alongside Terra and Luna, with Sol positioned as the flagship model for the most demanding tasks. The model introduces a new max reasoning effort for deeper thinking and an ultra mode that uses subagents to accelerate complex work beyond a single-agent approach. GPT-5.6 Sol shows strong performance in command-line coding workflows, long-horizon security tasks, genomics analysis, vulnerability research, debugging, patch development, and defensive testing. OpenAI pairs the model’s stronger capabilities with layered safeguards, real-time misuse classifiers, account-level review, automated red-teaming, and enterprise controls for sensitive workflows. GPT-5.6 Sol helps developers, enterprises, researchers, and security teams complete sophisticated technical work.
Learn more about GPT-5.6 Sol
Claude Opus 5.5
Claude Opus 5.5 is Anthropic’s advanced AI model for agentic coding, complex knowledge work, computer use, research, and long-running professional tasks. It is designed to handle large codebases, multi-step workflows, financial analysis, document creation, software audits, and other demanding workloads with improved efficiency over Claude Opus 5. Anthropic reports that Opus 5.5 uses fewer tokens per task, produces output more than 30% faster, and costs less to run than its predecessor. The model also improves communication quality by putting important information first, reducing unnecessary jargon, and following writing instructions more consistently. Safety enhancements include stronger prompt-injection resistance, action screening, sandboxing support, code review, behavioral alignment testing, and safeguards for high-risk cybersecurity & biology. Claude Opus 5.5 is available through Claude, Claude Code, the Claude Platform API, Amazon Web Services, Google Cloud, and Microsoft Azure.
Learn more about Claude Opus 5.5
GPT-6.1 Terra
GPT-6.1 Terra is a multimodal artificial intelligence model developed by OpenAI for visual reasoning, computer use, software development, and professional productivity tasks. The model combines image understanding, natural language processing, and precise interaction with graphical applications to execute complex workflows. Its visual reasoning capabilities support interpreting technical drawings, analyzing images, understanding application interfaces, and extracting information from documents. GPT-6.1 Terra can automate computer-based tasks such as completing forms, entering invoice information into accounting software, editing videos, and manipulating application interfaces. The model supports a context window of 1,050,000 tokens, configurable reasoning effort, function calling, structured outputs, and integrations with external tools through the OpenAI API.
Learn more about GPT-6.1 Terra
Pricing
Starting Price:
Free
Free Version:
Free Version available.
Integrations
No integrations listed.
Company Information
Meta
Founded: 2004
United States
github.com/facebookresearch/esm
Videos and Screen Captures
Other Useful Business Software
Our Free Plans just got better! | Auth0
You asked, we delivered! Auth0 is excited to expand our Free and Paid plans to include more options so you can focus on building, deploying, and scaling applications without having to worry about your security. Auth0 now, thank yourself later.
Product Details
Platforms Supported
Cloud
On-Premises
Training
Documentation
ESMFold Frequently Asked Questions
Q: What kinds of users and organization types does ESMFold work with?
ESMFold works with these users and organization types: Mid Size Business, Small Business, Enterprise, Freelance, Nonprofit, Government, and Startup.
Q: What languages does ESMFold support in their product?
ESMFold supports these languages: English.
Q: What type of training does ESMFold provide?
ESMFold provides training in the form of documentation.
Q: How much does ESMFold cost?
Pricing for ESMFold starts at Free.
