AlphaGenome 2Google DeepMind
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Evo 2Arc Institute
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Related Products
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AlphaGenome 2:
About
AlphaGenome 2 is an AI model and research software for analyzing how DNA sequence influences gene regulation and related molecular processes. It takes DNA sequence as input and predicts molecular properties, helping researchers investigate regulatory activity, gene expression, splicing, chromatin accessibility, and other genomic signals. It is designed for scientists studying gene function, genetic variant effects, and disease biology, including academic and other noncommercial research users. The model is available through an online API and developer tools for submitting sequences and retrieving predictions for computational analysis. Researchers can use predictions to prioritize hypotheses and inform follow-up experiments. AlphaGenome 2 is intended for research use only and has not been validated or approved for clinical or diagnostic purposes.
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Evo 2:
About
Evo 2 is a genomic foundation model capable of generalist prediction and design tasks across DNA, RNA, and proteins. It utilizes a frontier deep learning architecture to model biological sequences at single-nucleotide resolution, achieving near-linear scaling of compute and memory relative to context length. Trained with 40 billion parameters and a 1 megabase context length, Evo 2 processes over 9 trillion nucleotides from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function prediction across multiple biological modalities, including DNA, RNA, and proteins, and to generate novel sequences with plausible genomic architecture. The model's capabilities have been demonstrated in tasks such as designing functional CRISPR systems and predicting disease-causing mutations in human genes. Evo 2 is publicly accessible via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework.
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AlphaGenome 2:
Platforms Supported
Windows
Not Supported
Mac
Not Supported
Linux
Not Supported
Cloud
Supported
On-Premises
Not Supported
iPhone
Not Supported
iPad
Not Supported
Android
Not Supported
Chromebook
Not Supported
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Evo 2:
Platforms Supported
Windows
Not Supported
Mac
Not Supported
Linux
Not Supported
Cloud
Supported
On-Premises
Not Supported
iPhone
Not Supported
iPad
Not Supported
Android
Not Supported
Chromebook
Not Supported
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AlphaGenome 2:
Audience
Researchers and computational biologists studying gene regulation, genetic variants, and disease biology; the noncommercial access is aimed at research use.
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Evo 2:
Audience
Computational biologists and genetic engineers in need of a tool to model and design biological sequences across multiple modalities, enhancing research in genomics and synthetic biology
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AlphaGenome 2:
Support
Phone Support
Not Supported
24/7 Live Support
Not Supported
Online
Not Supported
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Evo 2:
Support
Phone Support
Not Supported
24/7 Live Support
Not Supported
Online
Supported
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AlphaGenome 2:
API
Offers API
Supported
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Evo 2:
API
Offers API
Not Supported
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AlphaGenome 2:
Screenshots and VideosNo images available
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Evo 2:
Screenshots and Videos |
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AlphaGenome 2:
PricingThe AlphaGenome API is free of charge for noncommercial use. Commercial research access is in private preview.
Free Version
Supported
Free Trial
Not Supported
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Evo 2:
Pricing
No information available.
Free Version
Not Supported
Free Trial
Not Supported
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AlphaGenome 2:
Reviews/
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Evo 2:
Reviews/
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AlphaGenome 2:
Training
Documentation
Supported
Webinars
Not Supported
Live Online
Not Supported
In Person
Not Supported
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Evo 2:
Training
Documentation
Supported
Webinars
Not Supported
Live Online
Not Supported
In Person
Supported
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AlphaGenome 2:
Company InformationGoogle DeepMind
Founded: 2010
United Kingdom
deepmind.google/science/alphagenome/
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Evo 2:
Company InformationArc Institute
United States
arcinstitute.org/tools/evo
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AlphaGenome 2:
Alternatives |
Evo 2:
Alternatives |
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Evo 2:
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AlphaGenome 2:
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Evo 2:
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AlphaGenome 2:
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Evo 2: | |||||
AlphaGenome 2:
Categories |
Evo 2:
Categories |
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AlphaGenome 2:
Integrations
Evo Designer
Not Supported
GitHub
Not Supported
Hugging Face
Not Supported
NVIDIA BioNeMo
Not Supported
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Evo 2:
Integrations
Evo Designer
Supported
GitHub
Supported
Hugging Face
Supported
NVIDIA BioNeMo
Supported
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AlphaGenome 2:
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Evo 2:
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