WellMeth

WellMeth is a integrated framework for Reduced Representation Bisulfite-Seq analysis

Features

Expands the Genotyping by Sequencing (GBS) approach to the detection of methylated cytosines in genomic DNA
Relies on the availability of high-quality reference genomes and for library construction double restriction digest with two methylation-insensitive enzymes is recommended
For paired-end short-read sequencing asymmetric forward- and reverse adapters will be applied with 4 to 6 nt long barcodes and a fixed number of random nucleotides (Unique Molecular Identifiers, UMIs) adjacent to the barcodes
UMI information will be used for post-alignment identification of PCR duplicates
Consists of four overlaying modules: Preprocessing, Mapping, Methylation variant detection and Differential methylation
Modules are interconnected by customizable wrapper scripts allowing fully automated execution
Fast, accurate and lightweight

Project Activity

See All Activity >

License

Creative Commons Attribution ShareAlike License V3.0

Follow WellMeth

WellMeth Web Site

Other Useful Business Software

$300 Free Credits for Your Google Cloud Projects

Start building on Google Cloud with $300 in free credits. No commitment, no credit card required until you're ready to scale.

Launch your next project with $300 in free Google Cloud credits—no strings attached. Test, build, and deploy without risk. Use your credits across the entire Google Cloud platform to find what works best for your needs. After your credits are used, continue with always-free tier services. Only pay when you're ready to scale. Sign up in minutes and start exploring.

Start Free Trial

Rate This Project

User Reviews

Be the first to post a review of WellMeth!

Additional Project Details

Operating Systems

Linux

Languages

English

User Interface

Console/Terminal

Registered

2020-05-08

Similar Business Software

OmnibusX

In the world of biological data science, navigating vast and complex datasets can be a daunting task. Our software toolkit is designed to empower you by accelerating analysis, promoting accessibility, and providing comprehensive visualization tools to help you make sense of these intricate...

See Software
OmicsBox

OmicsBox is a leading bioinformatics solution that offers end-to-end data analysis of genomes, transcriptomes, metagenomes, and genetic variation studies. The application is used by top private and public research institutions worldwide and allows researchers to easily process large and complex...

See Software
Edison Analysis

Edison Analysis is a next-generation scientific data-analysis agent built by Edison Scientific. It is the analytical engine underpinning their AI Scientist platform, Kosmos, and it’s available both on Edison’s platform and via API. Edison Analysis performs complex scientific data analysis by...

See Software
Geneious

Geneious Prime makes bioinformatics accessible by transforming raw data into visualizations that make sequence analysis intuitive and user-friendly. Simple sequence assembly and easy editing of contigs. Automatic annotation for gene prediction, motifs, translation, and variant calling. Genotype...

See Software
MEGA

MEGA (Molecular Evolutionary Genetics Analysis) is a powerful and user-friendly software suite designed for analyzing DNA and protein sequence data from species and populations. It facilitates both automatic and manual sequence alignment, phylogenetic tree inference, and evolutionary hypothesis...

See Software
Bioconductor

The Bioconductor project aims to develop and share open source software for precise and repeatable analysis of biological data. We foster an inclusive and collaborative community of developers and data scientists. Resources to maximize the potential of Bioconductor. From basic functionalities to...

See Software