MethylExtract is a user friendly tool to generate i) high quality, whole genome methylation maps and ii) to detect sequence variation within the same sample preparation. The program is implemented into a single script and takes into account all major error sources: sequencing errors, bisulfite failure, clonal reads and single nucleotide variants. MethylExtract detects variation (SNVs – Single Nucleotide Variation) in a similar way than VarScan, a very sensitive method extensively used in SNP and genotype calling based on non-bisulfite treated reads.
Features
- Methylation and SNV calling from NGS BS-Seq experiments
- Detects and removes potential PCR duplicates
- Putative bisulfite failures detection
- Sequencing errors control
- Statistical bisulfite failure assessment
- Bisulfite SAM / BAM files processing
- Multithreading and memory control
Categories
Bio-InformaticsFollow MethylExtract
Other Useful Business Software
$300 Free Credits to Build on Google Cloud
Start your next project with $300 in free Google Cloud credit. Spin up VMs, run containers, query petabytes in BigQuery, or build agents with Gemini Enterprise Agent Platform. Once your credits are used, keep building with 20+ always-free tier products including Compute Engine, Cloud Storage, GKE, and Cloud Run functions. No commitment required—just sign up and start building.
Rate This Project
Login To Rate This Project
User Reviews
Be the first to post a review of MethylExtract!