Stochastic simulation model of poliovirus Sabin-to-Mahoney genetic state transition (C++ code). Models genotypes, virus populations, and quasispecies cloud. Simulates replication error and copy-choice recombination. Various parameters guiding the model are user-specified. Python code post-processes simulation output to produce report files.

Features

  • Simulates Picornavirus replication error and copy-choice recombination
  • Represents genotypes, cell populations, and quasispecies cloud
  • Allows user control of parameters: MOI, replication error rate, recombination rate, generational growth rate, burst size, number of passages, number of cells, fitness acceleration, Mahoney mutational synergy
  • Reports population diversity, average fitness, neurovirulence, Mahoney resemblence

Project Activity

See All Activity >

Categories

Bio-Informatics

License

GNU General Public License version 3.0 (GPLv3)

Follow Virus QSP Modeling

Virus QSP Modeling Web Site

You Might Also Like
High-performance Open Source API Gateway Icon
High-performance Open Source API Gateway

KrakenD is a stateless, distributed, high-performance API Gateway that helps you effortlessly adopt microservices

KrakenD is a high-performance API Gateway optimized for resource efficiency, capable of managing 70,000 requests per second on a single instance. The stateless architecture allows for straightforward, linear scalability, eliminating the need for complex coordination or database maintenance.
Learn More
Rate This Project
Login To Rate This Project

User Reviews

Be the first to post a review of Virus QSP Modeling!

Additional Project Details

Intended Audience

Science/Research, Education, Advanced End Users, Developers

Programming Language

Python, C++

Related Categories

Python Bio-Informatics Software, C++ Bio-Informatics Software

Registered

2016-02-19
Report inappropriate content