Stochastic simulation model of poliovirus Sabin-to-Mahoney genetic state transition (C++ code). Models genotypes, virus populations, and quasispecies cloud. Simulates replication error and copy-choice recombination. Various parameters guiding the model are user-specified. Python code post-processes simulation output to produce report files.
Features
- Simulates Picornavirus replication error and copy-choice recombination
- Represents genotypes, cell populations, and quasispecies cloud
- Allows user control of parameters: MOI, replication error rate, recombination rate, generational growth rate, burst size, number of passages, number of cells, fitness acceleration, Mahoney mutational synergy
- Reports population diversity, average fitness, neurovirulence, Mahoney resemblence
Categories
Bio-InformaticsLicense
GNU General Public License version 3.0 (GPLv3)Follow Virus QSP Modeling
Other Useful Business Software
Earn up to 16% annual interest with Nexo.
Put idle assets to work with competitive interest rates, borrow without selling, and trade with precision. All in one platform.
Geographic restrictions, eligibility, and terms apply.
Rate This Project
Login To Rate This Project
User Reviews
Be the first to post a review of Virus QSP Modeling!