1. What is NgAgo-gDNA bioinformatic tool?
Natronobacterium gregoryi Argonaute (NgAgo) is a DNA-guided endonuclease suitable for genome editing in human cells. NgAgo binds 5' phosphorylated single-stranded guide DNA (gDNA) of ∼24 nucleotides, efficiently creates site-specific DNA double-strand breaks when loaded with the gDNA. The NgAgo-gDNA system does not require a protospacer-adjacent motif (PAM), as does Cas9(Gao et al., 2016 Nat Biotechnol). Based on these features, NgAgo-gDNA was developed, which is a bioinformatic tool for fast designing gDNA and evaluating potential off-target cleavage sites.

2. Where is the homepage of NgAgo-gDNA?
www.ngago-gdna.org (in prepare)
or http://www.biootools.com/col.jsp?id=178

NgAgo-gDNA design source code free for academic, nonprofit, and personal use.

If you use this program in your research, please cite:
Xie et al., 2016. NgAgo-gDNA: a tool for fast designing gDNA and evaluating potential off-target cleavage sites. In prepare.

Project Activity

See All Activity >

Follow NgAgo-gDNA

NgAgo-gDNA Web Site

Other Useful Business Software
Fully Managed MySQL, PostgreSQL, and SQL Server Icon
Fully Managed MySQL, PostgreSQL, and SQL Server

Automatic backups, patching, replication, and failover. Focus on your app, not your database.

Cloud SQL handles your database ops end to end, so you can focus on your app.
Try Free
Rate This Project
Login To Rate This Project

User Reviews

Be the first to post a review of NgAgo-gDNA!

Additional Project Details

Registered

2016-05-20
Report inappropriate content