To facilitate the comparison of gene essentialities in two or more cell samples, we propose MoPAC (Modular Pipeline for Analysis of CRISPR screens), a Shiny-driven interactive tool for differential essentiality analysis in CRISPR/Cas9 screens.

For installation and usage instructions please refer to the wiki page.

Features

  • Unbiased measurement of differential gene essentiality in CRISPR screens.
  • Ease of use through an interactive graphical user interphase.
  • Publication-ready figures generated at every step of the analysis.
  • Both FASTQ files and read-count tables (before or after normalization) allowed as input.
  • Gene-category-based quality control for outlier detection and filtering.
  • Gene ontology analysis built-in through the STRINGdb R package.
  • Fast processing through C++ compilation of calculation-intensive steps.

Project Samples

Project Activity

See All Activity >

Categories

Bio-Informatics

License

GNU General Public License version 3.0 (GPLv3)

Follow MoPAC

MoPAC Web Site

Other Useful Business Software
Build Securely on AWS with Proven Frameworks Icon
Build Securely on AWS with Proven Frameworks

Lay a foundation for success with Tested Reference Architectures developed by Fortinet’s experts. Learn more in this white paper.

Moving to the cloud brings new challenges. How can you manage a larger attack surface while ensuring great network performance? Turn to Fortinet’s Tested Reference Architectures, blueprints for designing and securing cloud environments built by cybersecurity experts. Learn more and explore use cases in this white paper.
Download Now
Rate This Project
Login To Rate This Project

User Reviews

Be the first to post a review of MoPAC!

Additional Project Details

Intended Audience

Science/Research

User Interface

Web-based

Programming Language

C++, S/R

Related Categories

C++ Bio-Informatics Software, S/R Bio-Informatics Software

Registered

2018-07-20