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GRASPER (Genome Rearrangement Analysis using Short Paired-End Reads) is a de novo structural variation (SV) calling software that is capable of detecting repetitive SVs.
It constructs A-Bruijn graphs to capture approximate repeats within a reference genome then SVs are detected on the graphs.
GRASPER requires a reference genome sequence in a FASTA formatted file along with a Illumina paired-end sequencing data of a sample genome.
Features
- Repetitive SV calling
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