LoopMatcher is a bioinformatics tool that searches for hairpin structures in cDNA / mRNA sequences (in FASTA, GenBank or Vienna format) with specific consensus sequences in the loop. It uses RNAfold to predict sequence structure and UShuffle to generate random sequences with a defined k nucleotide frequency. Also, sequences in GenBank format can be downloaded directly from NCBI using the NCBI access ID.

Requirements
JAVA Runtime 8. It's highly recommended to have a multicore processor to process large sequences.
* Currently, this version only runs in Windows x64.

Features

  • Support to GenBank, FASTA and Vienna format files
  • Process one or multiple files
  • Get and process sequences from NCBI
  • Seek for multiple patterns using the FASTA IUPAC code for nucleotides
  • Generate shuffled versions with a k-let parameter (Ushuffle algorithm)
  • Results in a CSV format table
  • Two modes of folding, localized or global (entire sequence)
  • Folding with RNAFold (minimum free energy structure)

Project Samples

Project Activity

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Categories

Bio-Informatics

License

GNU Library or Lesser General Public License version 3.0 (LGPLv3)

Follow LoopMatcher

LoopMatcher Web Site

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Additional Project Details

Operating Systems

Windows

Intended Audience

Education, Science/Research

User Interface

Java Swing

Programming Language

Java

Database Environment

Flat-file

Related Categories

Java Bio-Informatics Software

Registered

2019-11-22